Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Linian Pan"'
Autor:
Syeda Kubra, Haiyang Zhang, Youwen Si, Xiao Gao, Tianzhen Wang, Linian Pan, Lei Li, Nanzhe Zhong, Junjiang Fu, Bianhong Zhang, Xiaotao Li
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Endogenous clocks generate rhythms in gene expression, which facilitates the organisms to cope through periodic environmental variations in accordance with 24-h light/dark time. A core question that needs to be elucidated is how such rhythms
Externí odkaz:
https://doaj.org/article/95ec2bfeaab64192ba59bcab15a7e6e8
Autor:
Xiao Gao, Qingwei Wang, Ying Wang, Jiang Liu, Shuang Liu, Jian Liu, Xingli Zhou, Li Zhou, Hui Chen, Linian Pan, Jiwei Chen, Da Wang, Qing Zhang, Shihui Shen, Yu Xiao, Zhipeng Wu, Yiyun Cheng, Geng Chen, Syeda Kubra, Jun Qin, Lan Huang, Pei Zhang, Chuangui Wang, Robb E. Moses, David M. Lonard, Bert W. O’ Malley, Fuad Fares, Bianhong Zhang, Xiaotao Li, Lei Li, Jianru Xiao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
How the REGγ-proteasome pathway is regulated during the cell cycle or genotoxic insults remains unclear. Here, the authors show that NIP30 acts as a molecular switch to regulate the REGγ-proteasome activity and may provide an approach to combat dru
Externí odkaz:
https://doaj.org/article/7b5a15238e124a499bbec73fb760c725
Autor:
Xiao Gao, Qingwei Wang, Ying Wang, Jiang Liu, Shuang Liu, Jian Liu, Xingli Zhou, Li Zhou, Hui Chen, Linian Pan, Jiwei Chen, Da Wang, Qing Zhang, Shihui Shen, Yu Xiao, Zhipeng Wu, Yiyun Cheng, Geng Chen, Syeda Kubra, Jun Qin, Lan Huang, Pei Zhang, Chuangui Wang, Robb E. Moses, David M. Lonard, Bert W. O’ Malley, Fuad Fares, Bianhong Zhang, Xiaotao Li, Lei Li, Jianru Xiao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/a9b4ebd46ecc442db6f2ac93d22cbc3e
Autor:
Youwen Si, Lei Li, Bianhong Zhang, Nanzhe Zhong, Xiaotao Li, Tianzhen Wang, Linian Pan, Junjiang Fu, Haiyang Zhang, Syeda Kubra, Xiao Gao
Publikováno v:
Cell Death Discovery
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Cell Death Discovery, Vol 7, Iss 1, Pp 1-10 (2021)
Endogenous clocks generate rhythms in gene expression, which facilitates the organisms to cope through periodic environmental variations in accordance with 24-h light/dark time. A core question that needs to be elucidated is how such rhythms prolifer
Autor:
Ke Li, Robb E. Moses, Pei Zhang, Xiaotao Li, Junjiang Fu, Tianzhen Wang, Quan Huang, Qingwu Liu, Lei Li, Tingmei Huang, Shaofang Xie, Geng Chen, Shihui Shen, Xiao Yang, Linian Pan, Lu Tong
Publikováno v:
Cell Death Differ
Lung cancer is one of the cancers with highest morbidity and mortality rates and the metastasis of lung cancer is a leading cause of death. Mechanisms of lung cancer metastasis are yet to be fully understood. Herein, we demonstrate that mice deficien
Autor:
Qing Zhang, Bianhong Zhang, Jiwei Chen, Robb E. Moses, Jun Qin, Ying Wang, Lei Li, Shuang Liu, Jiang Liu, Qingwei Wang, Xingli Zhou, David M. Lonard, Pei Zhang, Yiyun Cheng, Linian Pan, Da Wang, Jianru Xiao, Syeda Kubra, Chuangui Wang, Geng Chen, Yu Xiao, Lan Huang, Jian Liu, Zhipeng Wu, Fuad Fares, Li Zhou, Hui Chen, Bert W. O’ Malley, Xiaotao Li, Xiao Gao, Shihui Shen
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature communications, vol 11, iss 1
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature communications, vol 11, iss 1
A major challenge in chemotherapy is chemotherapy resistance in cells lacking p53. Here we demonstrate that NIP30, an inhibitor of the oncogenic REGγ-proteasome, attenuates cancer cell growth and sensitizes p53-compromised cells to chemotherapeutic
Autor:
Shuang Liu, Lan Huang, Qingwei Wang, Jun Qin, Bianhong Zhang, Bert W. O’ Malley, Li Zhou, Yu Xiao, Yiyun Cheng, Da Wang, Xingli Zhou, Chuangui Wang, Xiaotao Li, Jianru Xiao, Geng Chen, Fuad Fares, Pei Zhang, Hui Chen, Xiao Gao, Robb E. Moses, Shihui Shen, Jian Liu, Ying Wang, Lei Li, Jiang Liu, David M. Lonard, Qing Zhang, Linian Pan, Syeda Kubra, Jiwei Chen, Zhipeng Wu
Publikováno v:
Nature communications, vol 11, iss 1
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
A major challenge in chemotherapy is chemotherapy resistance in cells lacking p53. Here we demonstrate that NIP30, an inhibitor of the oncogenic REGγ-proteasome, attenuates cancer cell growth and sensitizes p53-compromised cells to chemotherapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae26a81a122dcb00fda05db7661c1a86
https://escholarship.org/uc/item/5sr7j8wr
https://escholarship.org/uc/item/5sr7j8wr
Publikováno v:
Cellular signalling. 64
Thyroid cancer is the most common endocrine cancer with an increasing incidence and mortality. Epithelial-mesenchymal transition (EMT) is a biological process contributing to tumor progression, metastasis, and the acquisition of chemotherapy resistan
Autor:
Lei Li, Liangfang Yao, Bhatti Muhammad Zeeshan, Yongyan Dang, Tenghui Chen, Tingmei Huang, Di Zuo, Abdus Saboor Shah, Linian Pan, Tielong Liu, Qingwei Wang, Geng Chen, Zhengwang Sun, Jiwei Chen, Kun Li, Jian Liu, Lu Tong, Ke Li, Chan Jiao, Kewen Hu, Hui Chen, Xiao Gao
Publikováno v:
Experimental dermatology. 26(11)
It has been reported that the proteasome activator REGγ is associated with multiple oncogenic pathways in human cancers. However, the role of REGγ in the development of melanoma and the underlying mechanisms remain unclear. In this study, we attemp