Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Linhui Zhai"'
Autor:
Hao Hu, Wei Hu, An-Di Guo, Linhui Zhai, Song Ma, Hui-Jun Nie, Bin-Shan Zhou, Tianxian Liu, Xinglong Jia, Xing Liu, Xuebiao Yao, Minjia Tan, Xiao-Hua Chen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Protein-modifying enzymes regulate the dynamics of myriad post-translational modification (PTM) substrates. Precise characterization of enzyme-substrate associations is essential for the molecular basis of cellular function and phenotype. Me
Externí odkaz:
https://doaj.org/article/8bb6d3a208b74d10b4baab4eeb0afdf9
Autor:
Zhongwei Xu, Kaiyuan Fan, Heng Li, Lulu Wang, Wenqing Zhu, Shuang Zou, Yan Zhang, Yanan Liu, Zhidong Wu, Qian Gong, Minjia Tan, Jin Wang, Linhui Zhai
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30433- (2024)
Salidroside (SAL), belonging to a kind of the main active ingredient of Rhodiola rosea, is extensively utilized for anti-hypoxia and prevention of altitude sickness in the plateau region of China. However, the research on the systemic changes induced
Externí odkaz:
https://doaj.org/article/5f9e9a5568f64c8f9ee8ebcc9fc97a43
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
High-throughput profiling of protein C-termini is still a challenging task. Proteomics provides a powerful technology for systematic and high-throughput study of protein C-termini. Various C-terminal peptide enrichment strategies based on chemical de
Externí odkaz:
https://doaj.org/article/4e8c78bc30be480bbeaf148174448359
Autor:
Bin Liu, Shangwen Jiang, Min Li, Xuelian Xiong, Mingrui Zhu, Duanzhuo Li, Lei Zhao, Lili Qian, Linhui Zhai, Jing Li, Han Lu, Shengnan Sun, Jiandie Lin, Yan Lu, Xiaoying Li, Minjia Tan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Ubiquitin-specific protease 14 (USP14) is a proteasome-associated deubiquitinating enzyme with known roles in physiology and disease. Here the authors show that fatty acid synthase (FASN) is a substrate of USP14, and that by stabilizing FASN, it play
Externí odkaz:
https://doaj.org/article/3581473922f6403895adb5219d0ee52b
Autor:
Lulu Pan, Xijun Wang, Longhai Yang, Lei Zhao, Linhui Zhai, Junyu Xu, Yikun Yang, Yousheng Mao, Shujun Cheng, Ting Xiao, Minjia Tan
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Lung squamous cell carcinoma (LUSC) is one of the leading causes of tumor-driven deaths in the world. To date, studies on the tumor heterogeneity of LUSC at genomic level have only revealed limited therapeutic benefits. Therefore, system-wide researc
Externí odkaz:
https://doaj.org/article/789c8fa2a88d4448b98a7db525a49fab
Publikováno v:
mSystems, Vol 5, Iss 1 (2020)
ABSTRACT Cholesterol of the host macrophage membrane is vital for mycobacterial infection, replication, and persistence. During chronic infection within host lung tissues, cholesterol facilitates the phagocytosis of mycobacteria into macrophages. Cho
Externí odkaz:
https://doaj.org/article/fcb9f28a76c241dcae52900337e6d3af
Autor:
Lingsheng Chen, Linhui Zhai, Yanchang Li, Ning Li, Chengpu Zhang, Lingyan Ping, Lei Chang, Junzhu Wu, Xiangping Li, Deshun Shi, Ping Xu
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0115862 (2015)
The human serum proteome has been extensively screened for biomarkers. However, the large dynamic range of protein concentrations in serum and the presence of highly abundant and large molecular weight proteins, make identification and detection chan
Externí odkaz:
https://doaj.org/article/097d06a9c6834d419b0f9f841162a41a
Autor:
An-Di Guo, Ke-Nian Yan, Hao Hu, Linhui Zhai, Teng-Fei Hu, Haixia Su, Yijia Chi, Jinyin Zha, Yechun Xu, Dongxin Zhao, Xiaojie Lu, Yong-Jiang Xu, Jian Zhang, Minjia Tan, Xiao-Hua Chen
Publikováno v:
Nature Chemistry.
Autor:
Yang Sun, Qianqian Liu, Mingrui Han, Zhigui Wu, Wenqiang Fu, Jun Ji, Qingqing Liang, Minjia Tan, Linhui Zhai, Jian Gao, Dongquan Shi, Qing Jiang, Ziying Sun, Yuping Lai, Qiang Xu
Hyaline cartilage fibrosis is one of the important reasons for the poor prognosis of advanced osteoarthritis (OA), and is the main factor leading to joint stiffness and deformity. However, the mechanism of hyaline cartilage fibrosis remains largely u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fc4d89f5fd08e4f7d0ff49f6fee50e5
https://doi.org/10.21203/rs.3.rs-2811502/v1
https://doi.org/10.21203/rs.3.rs-2811502/v1
Autor:
Mingzhi Zhao, Fenghua Gao, Ren Suping, Bai Shanshan, Qi Yue, Xingwei Jiang, Honghao Li, Pinghuang Liu, Qun Yu, Linhui Zhai, Hongyu Liu, Liang Li, Hongwei Xu, Minjia Tan, Ying Zhang, Liying Zhang
Publikováno v:
Journal of Proteome Research. 19:3697-3707
Type III interferon (IFN-λ) is currently considered to be largely nonredundant to type I interferon (IFN-α) in antivirus infection, especially in epithelial cells. Previous studies reported that, compared with IFN-α, IFN-λ exhibited stronger indu