Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Linh Q Lam"'
Autor:
Jianfang Chen, Eileen Marks, Barry Lai, Zhaojie Zhang, James A Duce, Linh Q Lam, Irene Volitakis, Ashley I Bush, Steven Hersch, Jonathan H Fox
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77023 (2013)
Huntington's disease (HD) is a progressive neurodegenerative disorder caused by a polyglutamine-encoding CAG expansion in the huntingtin gene. Iron accumulates in the brains of HD patients and mouse disease models. However, the cellular and subcellul
Externí odkaz:
https://doaj.org/article/65ddefe2e67e47bbae30df0469525f4e
Publikováno v:
The World Journal of Biological Psychiatry. 21:119-126
Objectives: The objective of this study was to determine whether a breakdown in proteins regulating cortical iron homeostasis could be involved in the pathophysiology of mood disorders.Methods: Lev...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce88abff663a88604a78d27d16fc2940
https://doi.org/10.1080/15622975.2018.1555377
https://doi.org/10.1080/15622975.2018.1555377
Publikováno v:
Journal of Affective Disorders. 243:539-544
Background Changes in levels of metals have been suggested to contribute to the pathophysiologies of several neurodegenerative disorders but to our knowledge this is the first metallomic study in CNS from patients with mood disorders. The focus of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8ca8ca2312ac5a1637174ff2c6da95
https://doi.org/10.1016/j.jad.2018.09.026
https://doi.org/10.1016/j.jad.2018.09.026
Autor:
Steven J. Collins, Qiao-Xin Li, James A. Duce, Linh Q Lam, Bruce X. Wong, Tony Frugier, Peter J Crack, Ashley I. Bush
Publikováno v:
ACS Chemical Neuroscience. 8:731-736
Ferroxidase activity has been reported to be altered in various biological fluids in neurodegenerative disease, but the sources contributing to the altered activity are uncertain. Here we assay fractions of serum and cerebrospinal fluid with a newly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cca065cd662f31edb683b90be91eab0
https://doi.org/10.1021/acschemneuro.6b00411
https://doi.org/10.1021/acschemneuro.6b00411
Autor:
Scott Ayton, Bruce X. Wong, David Devos, Andrew Tsatsanis, Adam P Gunn, Linh Q Lam, James A. Duce, Ashley I. Bush
Publikováno v:
Alzheimer's & Dementia. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56da06410bc4757923310a6b7bb1205a
https://doi.org/10.1016/j.jalz.2017.06.1365
https://doi.org/10.1016/j.jalz.2017.06.1365
Publikováno v:
Metals in the Brain ISBN: 9781493969166
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8a00d14da533ac4d4dc258581ea88bf
https://doi.org/10.1007/978-1-4939-6918-0_10
https://doi.org/10.1007/978-1-4939-6918-0_10
Autor:
SinChun Lim, James A. Duce, Linh Q Lam, James L. Hickey, Nicki A. Sherratt, Kevin J. Barnham, David Finkelstein, Qiao-Xin Li, Bradley J. Turner, Julia Morizzi, Laura Bica, Andrew K. Powell, Janetta G. Culvenor, Cynthia P.W. Soon, Colin L. Masters, Paul S. Donnelly, Anthony R. White, Lin W. Hung, Jiang-Li Tan, Nastasia K. H. Lim, Peter J. Crouch
Publikováno v:
Journal of Biological Chemistry. 286:44035-44044
Amyotrophic lateral sclerosis (ALS) is a progressive paralyzing disease characterized by tissue oxidative damage and motor neuron degeneration. This study investigated the in vivo effect of diacetylbis(N(4)-methylthiosemicarbazonato) copper(II) (CuII
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d3e146a057bdd7c280b695b4c33a126
https://doi.org/10.1074/jbc.m111.274407
https://doi.org/10.1074/jbc.m111.274407
Autor:
Bruce X. Wong, Ashley I. Bush, Peng Lei, Linh Q Lam, James A. Duce, Scott Ayton, Paul A. Adlard
Publikováno v:
Biochimica et biophysica acta. 1840(12)
Background Iron oxidation is thought to be predominantly handled enzymatically in the body, to minimize spontaneous combustion with oxygen and to facilitate cellular iron export by loading transferrin. This process may be impaired in disease, and req
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8e84a800f78ea52dc3db08159e9abe
https://pubmed.ncbi.nlm.nih.gov/25152357
https://pubmed.ncbi.nlm.nih.gov/25152357
Autor:
Ashley I. Bush, Blaine R. Roberts, James A. Duce, Monica Lind, Peter J Crack, Scott Ayton, Tony Frugier, Moses Zhang, Catriona McLean, Linh Q Lam
Publikováno v:
Free radical biologymedicine. 69
Traumatic brain injury (TBI) is in part complicated by pro-oxidant iron elevation independent of brain hemorrhage. Ceruloplasmin (CP) and β-amyloid protein precursor (APP) are known neuroprotective proteins that reduce oxidative damage through iron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cccae6eef3e13634016c01c11c240d7b
https://pubmed.ncbi.nlm.nih.gov/24509156
https://pubmed.ncbi.nlm.nih.gov/24509156
Autor:
James A. Duce, Irene Volitakis, Jianfang Chen, Barry Lai, Steven J. Hersch, Jonathan H. Fox, Zhaojie Zhang, Eileen S. Marks, Linh Q Lam, Ashley I. Bush
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 11 (2013)
PLoS ONE, Vol 8, Iss 11 (2013)
The second and last authors were incorrectly indicated as having contributed equally to the article. In addition, the first author, Jianfeng Chen, was not correctly indicated as having contributed equally to the article with the second author, Eileen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c21e72c4b04d95cb0421b4c3e7bfe48
http://europepmc.org/articles/PMC3829977
http://europepmc.org/articles/PMC3829977