Zobrazeno 1 - 10 of 112 pro vyhledávání: '"Linh M. Tran"'
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Akademický článek
CCL21-DC in situ vaccination in murine NSCLC overcomes resistance to immunotherapy and generates systemic tumor-specific immunity
Autor: Bin Liu, Rui Li, Edward B Garon, Steven M Dubinett, Kostyantyn Krysan, Tianhao Zhang, Aaron E Lisberg, Ramin Salehi-Rad, Raymond J Lim, Yushen Du, Linh M Tran, Stephanie L Ong, Zi Ling Huang, Camelia Dumitras, Stacy J Park, William Crosson, Bitta Kahangi, Jensen Abascal, Christopher Seet, Michael Oh, Maryam Shabihkhani, Manash Paul
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 9 (2023)
Background Despite recent advances in immunotherapy, many patients with non-small cell lung cancer (NSCLC) do not respond to immune checkpoint inhibitors (ICI). Resistance to ICI may be driven by suboptimal priming of antitumor T lymphocytes due to p
Externí odkaz: https://doaj.org/article/bf2a559715ab4836a9534c935ea67e88
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Data from Cell Intrinsic Role of COX-2 in Pancreatic Cancer Development
Autor: Hong Wu, Harvey R. Herschman, Timothy R. Donahue, Ying Wang, Christine Kim, Alejandro Garcia, Joseph Hargan Calvopina, Sarah Dry, Linh M. Tran, Yunfeng Li, Reginald Hill
COX-2 is upregulated in pancreatic ductal adenocarcinomas (PDAC). However, how COX-2 promotes PDAC development is unclear. While previous studies have evaluated the efficacy of COX-2 inhibition via the use of nonsteroidal anti-inflammatory drugs (NSA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fd11d179bbc8dbf90385d34e174002
https://doi.org/10.1158/1535-7163.c.6535237.v1
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6
Supplementary Data from Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK
Autor: Timothy R. Donahue, David W. Dawson, Sanjeet G. Patel, Luyi Li, Mihir Bikhchandani, Linh M. Tran, Irmina Gawlas, Nanping Wu, Mindy Duong, Brian E. Kadera, Andrew H. Nguyen, Paul A. Toste
Figures S1-4 and Table S1 Figure S1. N-CAFs and R-CAFs were exposed to the indicated concentrations of gemcitabine for 72h, and viability was measured via MTT assay. 3 biologic replicates were included in the experiment. **p{less than or equal to}0.0
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d19086e5927a52fd27f158e064e6c66
https://doi.org/10.1158/1541-7786.22510923
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Data from Chemotherapy-Induced Inflammatory Gene Signature and Protumorigenic Phenotype in Pancreatic CAFs via Stress-Associated MAPK
Autor: Timothy R. Donahue, David W. Dawson, Sanjeet G. Patel, Luyi Li, Mihir Bikhchandani, Linh M. Tran, Irmina Gawlas, Nanping Wu, Mindy Duong, Brian E. Kadera, Andrew H. Nguyen, Paul A. Toste
Pancreatic ductal adenocarcinoma (PDAC) has a characteristically dense stroma comprised predominantly of cancer-associated fibroblasts (CAF). CAFs promote tumor growth, metastasis, and treatment resistance. This study aimed to investigate the molecul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::add05283f2d6ce93c4d3b7efba339821
https://doi.org/10.1158/1541-7786.c.6539775.v1
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