Epiregulin increases stemness-associated genes expression and promotes chemoresistance of non-small cell lung cancer via ERK signaling

Autor: Yujia Zhang, Fengjun Qiu, Tingjie Ye, Sau Har Lee, Jiatuo Xu, Lingyan Jia, Rui Zeng, Xiaoling Wang, Xudong Hu, Xiaofeng Yan, Hua Li, Yanlin Lu, Rilei Jiang, Wei Xu

Publikováno v: Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2022)

Abstract Background Chemoresistance often causes the failure of treatment and death of patients with advanced non-small-cell lung cancer. However, there is still no resistance genes signature and available enriched signaling derived from a comprehens

Externí odkaz: https://doaj.org/article/65ffa036591f4a838a0b087013f53d00

Simultaneous Determination and Quantification of Triterpene Saponins from Camellia sinensis Seeds Using UPLC-PDA-QTOF-MS/MS

Autor: Xuejin Wu, Lingyan Jia, Jiafan Wu, Yawen Liu, Hyunuk Kang, Xiaobo Liu, Pan Li, Puming He, Youying Tu, Bo Li

Publikováno v: Molecules, Vol 24, Iss 20, p 3794 (2019)

Saponins in the Camellia sinensis seeds have a broad spectrum of biological properties and application potentials. However, up to now, no chromatographic methods have been developed to provide full fingerprinting and quality assurance for these sapon

Externí odkaz: https://doaj.org/article/6bba023b86cd40cca1f015e6c3e4ea08

EREG increases stemness associated genes expression and promotes Chemoresistance of non-small cell lung cancer via ERK signaling

Autor: Wei Xu, Yujia Zhang, Fengjun Qiu, Tingjie Ye, Sau Har Lee, Jiatuo Xu, Lingyan Jia, Rui Zeng, Xiaoling Wang, Xudong Hu, Xiaofeng Yan, Hua Li, Yanlin Lu, Rilei Jiang

Background: Chemotherapy is the preferred approach for treatment of advanced non-small cell lung cancer (NSCLC), but it often resulted in acquired resistance, which led to the failure of treatment. Therefore, it is necessary to identify and remove th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dbad905164e567a150ade567c6b90f5d
https://doi.org/10.21203/rs.3.rs-1094551/v1

Simultaneous Determination and Quantification of Triterpene Saponins from Camellia sinensis Seeds Using UPLC-PDA-QTOF-MS/MS

Autor: Xiaobo Liu, Lingyan Jia, Youying Tu, Pan Li, Jiafan Wu, Yawen Liu, Wu Xuejin, Hyunuk Kang, Bo Li, Puming He

Publikováno v: Molecules
Molecules, Vol 24, Iss 20, p 3794 (2019)
Volume 24
Issue 20

Saponins in the Camellia sinensis seeds have a broad spectrum of biological properties and application potentials. However, up to now, no chromatographic methods have been developed to provide full fingerprinting and quality assurance for these sapon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aad5efa4bea629885a2cc760f07a29e
http://europepmc.org/articles/PMC6832586

Anti-Proliferation Effect of Theasaponin E1 on the ALDH-Positive Ovarian Cancer Stem-Like Cells

Autor: Casey Compton, Lingyan Jia, Yi Charlie Chen, Bo Li, Gary O. Rankin, Heather Bucur, Youying Tu, Zhi-Da Chen, Hui-Long Xia, Devendra A. Sawant

Publikováno v: Molecules, Vol 23, Iss 6, p 1469 (2018)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules
Volume 23
Issue 6

Ovarian cancer has the highest mortality rate of all gynecological malignancies and the five-year death rate of patients has remained high in the past five decades. Recently, with the rise of cancer stem cells (CSCs) theory, an increasing amount of r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b3caab38eb957cf7a75053664cfc0f
http://www.mdpi.com/1420-3049/23/6/1469