Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Lingxun Duan"'
Autor:
Ivan Garcia-Bassets, Jian-Bing Fan, Xiang-Dong Fu, Dong Wang, Dongyan Liu, Mingjie Jin, Christopher Benner, Kasey R. Hutt, Michael G. Rosenfeld, Lingxun Duan, Christopher K. Glass, Christine S. Cheng, Young-Soo Kwon, Marina Bibikova, Zhen Ye
Publikováno v:
Proceedings of the National Academy of Sciences. 104:4852-4857
ChIP coupled with microarray provides a powerful tool to determine in vivo binding profiling of transcription factors to deduce regulatory circuitries in mammalian cells. Aiming at improving the specificity and sensitivity of such analysis, we develo
Autor:
Roger J. Pomerantz, Lingxun Duan, YanNing Xue, Yves Baudat, Joséphine Sire, Baocheng Hu, Mohamad Bouhamdan
Publikováno v:
Journal of Biological Chemistry. 273:8009-8016
Targeting protein or RNA moieties to specific cellular compartments may enhance their desired functions and specificities. Human immunodeficiency virus type I (HIV-1) encodes proteins in addition to Gag, Pol, and Env that are packaged into virus part
Autor:
Roger J. Pomerantz, Brian R. Murphy, Glenn R. Pilkington, Lingxun Duan, James E. Crowe, Robert M. Chanock, Page S. Gilmour
Publikováno v:
The Journal of Infectious Diseases. 177:1073-1076
A second human respiratory syncytial virus (RSV)-neutralizing monoclonal antibody was isolated and its binding site was identified. Fab F2-5 is a broadly reactive fusion (F) protein-specific recombinant Fab generated by antigen selection from a rando
Publikováno v:
AIDS Research and Human Retroviruses. 12:1093-1101
The molecular mechanisms involved in the regulation of human immunodeficiency virus type 1 (HIV-1) replication may differ in various cell types and with various exogenous stimuli. TAR/Tat interactions play important roles in HIV-1-long terminal repea
Publikováno v:
Molecular Immunology. 33:439-450
A human Fab phage display library has been produced from peripheral blood lymphocytes of an individual who was asymptomatic after 10 years of infection with human immunodeficiency virus type-1 (HIV-1). The library was panned against the HIV-1 Rev and
Publikováno v:
Human Gene Therapy. 6:1561-1573
Genetic therapy offers a potentially promising approach with which to combat human immunodeficiency virus type 1 (HIV-1) infections. Several modalities, using protein- and RNA-based systems, have recently been shown to inhibit HIV-1 replication. A si
Publikováno v:
Human Gene Therapy. 5:1315-1324
A variety of genetic therapies or intracellular immunization techniques hold promise as modalities to inhibit human immunodeficiency virus type 1 (HIV-1) replication in vivo. We have recently demonstrated that a single-chain variable fragment (SFv) c
Publikováno v:
AIDS Research and Human Retroviruses. 10:1213-1219
Human immunodeficiency virus type 1 (HIV-1) replication is controlled by a complex array of virally encoded and cellular proteins. A wide spectrum of levels of HIV-1 expression have been demonstrated in various cells, both in cell culture and in vivo
Publikováno v:
Journal of Virology. 68:4302-4313
The p53 tumor suppressor gene product, a sequence-specific DNA-binding protein, has been shown to act as a transcriptional activator and repressor both in vitro and in vivo. Consistent with its role in regulating transcription are recent observations
Autor:
Lingxun Duan, Roger J. Pomerantz, Joseph Kulkosky, Huizhong Zhang, Pnina Levy-Mintz, Diane Bizub-Bender, Minghua Zhu, Geethanjali Dornadula, Baocheng Hu, Anna Marie Skalka
Publikováno v:
NIH guide for grants and contracts
Integration of viral DNA into a chromosome of the infected host cell is required for efficient replication of a retroviral genome, and this reaction is mediated by the virus-encoded enzyme integrase (IN). As IN plays a pivotal role in establishing in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda888be436209ecb5eeec40ac52bb5c
https://europepmc.org/articles/PMC114014/
https://europepmc.org/articles/PMC114014/