Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Lingxiong Wang"'
Autor:
Yaojun Peng, Lingxiong Wang, Juan Yang, Qiyan Wu, Xiaoxuan Sun, Jinying Zhang, Yanju Yu, Liping Zhang, Jie Gao, Qing Zhou, Haiyan Zhu, Fan Yin
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundInhibition of indolamine-2,3-dioxygenase 1 (IDO1) has been proposed as a promising strategy for cancer immunotherapy; however, it has failed in clinical trials. Macrophages in the tumor microenvironment (TME) contribute to immune escape and
Externí odkaz:
https://doaj.org/article/f743289e7a1d4d01a4a80a071933459b
Autor:
Yaojun Peng, Qiyan Wu, Xinhuan Ding, Lingxiong Wang, Hanpu Gong, Cong Feng, Tianyi Liu, Haiyan Zhu
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-13 (2023)
Abstract Background High throughput gene expression profiling is a valuable tool in providing insight into the molecular mechanism of human diseases. Hypoxia- and lactate metabolism-related genes (HLMRGs) are fundamentally dysregulated in sepsis and
Externí odkaz:
https://doaj.org/article/ad218cb6c2834febbb549b066e384780
Autor:
Yaojun Peng, Hongyu Liu, Qiyan Wu, Lingxiong Wang, Yanju Yu, Fan Yin, Cong Feng, Xuewen Ren, Tianyi Liu, Ling Chen, Haiyan Zhu
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background Glioma is the most common malignant primary brain tumor and is characterized by a poor prognosis and limited therapeutic options. ISG20 expression is induced by interferons or double-stranded RNA and is associated with poor progno
Externí odkaz:
https://doaj.org/article/25851a5e3c0d463887af31a139b8f2e5
Autor:
Liangliang Wu, Yiming Gao, Shengzhi Xie, Wan Ye, Yasushi Uemura, Rong Zhang, Yanju Yu, Jinfeng Li, Man Chen, Qiyan Wu, Pengfei Cui, Hongyu Liu, Shuai Mu, Yilan Li, Lingxiong Wang, Chunxi Liu, Jiahui Li, Lijun Zhang, Shunchang Jiao, Guoqing Zhang, Tianyi Liu
Publikováno v:
Translational Oncology, Vol 37, Iss , Pp 101775- (2023)
Purpose: This study aimed to screen biomarkers to predict the efficacy of programmed cell death 1 (PD-1) blockade immunotherapy combined with chemotherapy as neoadjuvant therapy for esophageal squamous cell carcinoma (ESCC). Methods: In the first sta
Externí odkaz:
https://doaj.org/article/baa18bcaa952461180a0e4e00f36ab02
Autor:
Yaojun Peng, Qiyan Wu, Hongyu Liu, Jinying Zhang, Qingru Han, Fan Yin, Lingxiong Wang, Qi Chen, Fei Zhang, Cong Feng, Haiyan Zhu
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSepsis is the leading cause of death in intensive care units and is characterized by multiple organ failure, including dysfunction of the immune system. In the present study, we performed an integrative analysis on publicly available data
Externí odkaz:
https://doaj.org/article/53474d4041ca4481ab5dd37376bac0c9
Autor:
Yaojun Peng, Qiyan Wu, Qing Zhou, Zhanglin Yang, Fan Yin, Lingxiong Wang, Qi Chen, Cong Feng, Xuewen Ren, Tianyi Liu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Severe trauma and sepsis can lead to multiple organ dysfunction syndrome, which is a leading cause of death in intensive care units with mortality rates in excess of 50%. In addition to infection, the degree of immuno-inflammatory response also influ
Externí odkaz:
https://doaj.org/article/d68f1496d1014715849f0d2ef500d1db
Autor:
Shaoping Shen, Ling Chen, Jialin Liu, Lin Yang, Mengna Zhang, Lingxiong Wang, Rong Zhang, Yasushi Uemura, Qiyan Wu, Xinguang Yu, Tianyi Liu
Publikováno v:
Cancer Biology & Medicine, Vol 17, Iss 3, Pp 555-568 (2020)
In the interaction between a tumor and the immune system, immune checkpoints play an important role, and in tumor immune escape, co-inhibitory immune checkpoints are important. Immune checkpoint inhibitors (ICIs) can enhance the immune system’s kil
Externí odkaz:
https://doaj.org/article/407aa98ee9684d968bde9686533069b8
Autor:
Qi Song, Quanbo Ji, Jingbo Xiao, Fang Li, Lingxiong Wang, Yin Chen, Yameng Xu, Shunchang Jiao
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 13, Iss , Pp 154-163 (2018)
Lung cancers, the leading cause of cancer mortality worldwide, are characterized by a high metastatic potential. Growing evidence reveals that Spindlin 1 (SPIN1) is involved in tumor progression and carcinogenesis. However, the role of SPIN1 in non-s
Externí odkaz:
https://doaj.org/article/be25e2a8d9574f93b01d19b35ef3d804
Autor:
Liangliang Wu, Shengzhi Xie, Lingxiong Wang, Jinfeng Li, Lu Han, Boyu Qin, Guoqing Zhang, Qiyan Wu, Wenjuan Gao, Lijun Zhang, Huafeng Wei, Tianyi Liu, Shunchang Jiao
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Antibodies against checkpoint inhibitors such as anti-programmed cell death protein 1 (PD-1) and its ligand anti-programmed death ligand 1 (PD-L1) have shown clinical efficacy in the treatment of multiple cancers. However, there are only a few studie
Externí odkaz:
https://doaj.org/article/fba403d5a1114677a394b95a09f94777
Autor:
Jingjing Duan, Yongwei Xie, Lijuan Qu, Lingxiong Wang, Shunkai Zhou, Yu Wang, Zhongyi Fan, Shengsheng Yang, Shunchang Jiao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 6, Iss 1, Pp 1-15 (2018)
Abstract Background Immunoscore, as a prognostic tool defined to quantify in situ immune cell infiltrates, appears to be superior to the TNM staging system. In esophageal squamous cell carcinoma (ESCC), no immunoscore has been established; however, i
Externí odkaz:
https://doaj.org/article/077cd3d36c314fb69a9cbd31047b36e9