Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lingui Gu"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Glioblastoma (GBM) is the most common malignant brain tumor and has a dismal prognosis even under the current first-line treatment, with a 5-year survival rate less than 7%. Therefore, it is important to understand the mechanism of treatment
Externí odkaz:
https://doaj.org/article/779856a2e1d140eaaa016ecc68d920a9
Autor:
Lingui Gu, Hualin Chen, Ruxu Geng, Tingyu Liang, Yihao Chen, Zhuo Wang, Liguo Ye, Mingjiang Sun, Qinglei Shi, Gui Wan, Jianbo Chang, Junji Wei, Wenbin Ma, Jiashun Xiao, Xinjie Bao, Renzhi Wang
Publikováno v:
Neurobiology of Disease, Vol 201, Iss , Pp 106695- (2024)
Background: Spontaneous intracerebral hemorrhage (ICH) is associated with alarmingly high rates of disability and mortality, and current therapeutic options are suboptimal. A critical component of ICH pathology is the initiation of a robust inflammat
Externí odkaz:
https://doaj.org/article/8734b0eb82ed47e6a271e3001e9c4c6c
Autor:
Lingui Gu, Hualin Chen, Mingjiang Sun, Yihao Chen, Qinglei Shi, Jianbo Chang, Junji Wei, Wenbin Ma, Xinjie Bao, Renzhi Wang
Publikováno v:
MedComm, Vol 5, Iss 7, Pp n/a-n/a (2024)
Abstract Intracerebral hemorrhage (ICH) poses a formidable challenge in stroke management, with limited therapeutic options, particularly in the realm of immune‐targeted interventions. Clinical trials targeting immune responses post‐ICH have enco
Externí odkaz:
https://doaj.org/article/355b714081f543faba705929d2ae538e
Autor:
Xiaopeng Guo, Lingui Gu, Yilin Li, Zhiyao Zheng, Wenlin Chen, Yaning Wang, Yuekun Wang, Hao Xing, Yixin Shi, Delin Liu, Tianrui Yang, Yu Xia, Junlin Li, Jiaming Wu, Kun Zhang, Tingyu Liang, Hai Wang, Qianshu Liu, Shanmu Jin, Tian Qu, Siying Guo, Huanzhang Li, Yu Wang, Wenbin Ma
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionGlioblastoma (GBM), the most lethal primary brain malignancy, is divided into histological (hist-GBM) and molecular (mol-GBM) subtypes according to the 2021 World Health Organization classification of central nervous system tumors. This s
Externí odkaz:
https://doaj.org/article/7e4f072b9a9d4cd7b3a2870cf17a6441
Autor:
Liguo Ye, Lingui Gu, Zhiyao Zheng, Xin Zhang, Hao Xing, Xiaopeng Guo, Wenlin Chen, Yaning Wang, Yuekun Wang, Tingyu Liang, Hai Wang, Yilin Li, Shanmu Jin, Yixin Shi, Delin Liu, Tianrui Yang, Qianshu Liu, Congcong Deng, Yu Wang, Wenbin Ma
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundThe World Health Organization (WHO) CNS5 classification system highlights the significance of molecular biomarkers in providing meaningful prognostic and therapeutic information for gliomas. However, predicting individual patient survival r
Externí odkaz:
https://doaj.org/article/bfe253aab9f7413b9bcd57f2291c822d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Intracerebral hemorrhage (ICH) is a major cerebrovascular illness that causes substantial neurological sequelae and dysfunction caused by secondary brain injury (SBI), and there are no effective therapies to mitigate the disability. Microglia, the br
Externí odkaz:
https://doaj.org/article/fe713526f0eb439491aa00a8025185b5
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Neuroinflammation has been proven to exert an important effect on brain injury after intracerebral hemorrhage (ICH). Previous studies reported that Didymin possessed anti-inflammatory properties after acute hepatic injury, hyperglycemia-induced endot
Externí odkaz:
https://doaj.org/article/ecd258325e4046bfbb7967e306809c07
Autor:
Lingui Gu, Hualin Chen, Ruxu Geng, Mingjiang Sun, Qinglei Shi, Yihao Chen, Jianbo Chang, Junji Wei, Wenbin Ma, Jiashun Xiao, Xinjie Bao, Renzhi Wang
Publikováno v:
International Journal of Biological Sciences; 2024, Vol. 21 Issue 10, p3842-3862, 21p
Publikováno v:
Journal of Neurochemistry. 165:426-444
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87b97463ee58b17ff2e62d6ea33b8073
https://doi.org/10.1111/jnc.15785
https://doi.org/10.1111/jnc.15785
Publikováno v:
Translational stroke research. 13(6)
Pyroptosis has been proven to be responsible for secondary brain injury after intracerebral hemorrhage (ICH). A recent study reported that Raf kinase inhibitor protein (RKIP) inhibited assembly and activation of inflammasome in macrophages. Our prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa4ca63a9031cc7039faa13cb94a690
https://pubmed.ncbi.nlm.nih.gov/35355228
https://pubmed.ncbi.nlm.nih.gov/35355228