Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Lingsheng Dong"'
Publikováno v:
PeerJ, Vol 6, p e4719 (2018)
Background Using DNA microarrays, we previously identified 451 genes expressed in 19 different human tissues. Although ubiquitously expressed, the variable expression patterns of these “housekeeping genes” (HKGs) could separate one normal human t
Externí odkaz:
https://doaj.org/article/40a9564ebf96416f80e0087592b643c4
Publikováno v:
Advances and Applications in Bioinformatics and Chemistry, Vol 2009, Iss default, Pp 17-22 (2009)
Lingsheng Dong1, Andrew J Bard1, William G Richards1, Matthew D Nitz2, Dan Theodorescu2, Raphael Bueno1, Gavin J Gordon11The Thoracic Surgery Oncology laboratory and the Division of Thoracic Surgery, Brigham and Women’s Hospital, Harvard Medical Sc
Externí odkaz:
https://doaj.org/article/eb4a95490f6a4890a3e7cd4be694a4b5
Autor:
Sangjun Moon, Yun-Gon Kim, Lingsheng Dong, Michael Lombardi, Edward Haeggstrom, Roderick V Jensen, Li-Li Hsiao, Utkan Demirci
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17455 (2011)
Technologies that rapidly isolate viable single cells from heterogeneous solutions have significantly contributed to the field of medical genomics. Challenges remain both to enable efficient extraction, isolation and patterning of single cells from h
Externí odkaz:
https://doaj.org/article/f0c4d02ea93546f7b709dede8d1046ce
Autor:
Raphael Bueno, Assunta De Rienzo, Lingsheng Dong, Gavin J Gordon, Colin F Hercus, William G Richards, Roderick V Jensen, Arif Anwar, Gautam Maulik, Lucian R Chirieac, Kim-Fong Ho, Bruce E Taillon, Cynthia L Turcotte, Robert G Hercus, Steven R Gullans, David J Sugarbaker
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10612 (2010)
The current paradigm for elucidating the molecular etiology of cancers relies on the interrogation of small numbers of genes, which limits the scope of investigation. Emerging second-generation massively parallel DNA sequencing technologies have enab
Externí odkaz:
https://doaj.org/article/091c3372829c4d0793ec38e8d8e5b809
Autor:
Kristina Holton, Lingsheng Dong, Ephraim F. Trakhtenberg, Jeffrey L. Goldberg, Nam Pho, Thomas Chittenden
Publikováno v:
Scientific Reports
Balance in the transcriptome is regulated by coordinated synthesis and degradation of RNA molecules. Here we investigated whether mammalian cell types intrinsically differ in global coordination of gene splicing and expression levels. We analyzed RNA
Autor:
Lingsheng Dong, Assunta De Rienzo, Gavin J. Gordon, William G. Richards, Raphael Bueno, Roderick V. Jensen, Beow Y. Yeap, David J. Sugarbaker
Publikováno v:
Clinical Cancer Research. 17:310-316
Purpose: Malignant pleural mesothelioma (MPM) is an aggressive disease associated with median survival between 9 and 12 months. The correct diagnosis of MPM is sometimes challenging and usually requires solid tissue biopsies rather than fine-needle a
Publikováno v:
PeerJ, Vol 6, p e4719 (2018)
PeerJ
PeerJ
Background Using DNA microarrays, we previously identified 451 genes expressed in 19 different human tissues. Although ubiquitously expressed, the variable expression patterns of these “housekeeping genes” (HKGs) could separate one normal human t
Autor:
Richard Colquitt, Lingsheng Dong, Beow Y. Yeap, William G. Richards, Gautam Maulik, Heather Edenfield, David J. Sugarbaker, Jonathan N. Glickman, Madhubalan Mani, Gavin J. Gordon, Branden Van Oss, Raphael Bueno
Publikováno v:
JNCI Journal of the National Cancer Institute. 101:678-686
Malignant pleural mesothelioma has few effective treatments, one being cytoreductive surgery. We previously developed a gene ratio test to predict outcome of malignant pleural mesothelioma patients undergoing surgery. In this study, we investigated t
Autor:
Lingsheng Dong, Beow Y. Yeap, Lipi Mukhopadhyay, David J. Sugarbaker, Raphael Bueno, Madhubalan Mani, Gavin J. Gordon
Publikováno v:
The Journal of Pathology. 211:439-446
Inhibitor of apoptosis proteins (IAPs) are overexpressed by most neoplasms and promote tumour cell survival after a wide variety of apoptotic stimuli elicited via intrinsic (ie mitochondrial) and extrinsic (ie death receptor) pathways. It has previou
Autor:
David J. Sugarbaker, Lingsheng Dong, Gavin J. Gordon, Madhubalan Mani, Beow Y. Yeap, Heather Edenfield, Raphael Bueno, Lipi Mukhopadhyay, Jonathan N. Glickman
Publikováno v:
The Journal of Pathology. 211:447-454
Inhibitor of apoptosis proteins (IAPs) comprise a family of structurally similar proteins, five of which are widely studied in the context of cancer: IAP-1/MIHC/cIAP2, IAP-2/MIHB/cIAP1, livin/ML-IAP/KIAP, survivin, and XIAP/MIHA/hILP. IAPs are overex