Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Lingpeng Zhu"'
Autor:
Hong-Ying Li, Ting-Ting Wei, Miao Zhuang, Cheng-Ye Tan, Tian-Hua Xie, Jiping Cai, Yong Yao, Lingpeng Zhu
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Cellular senescence is a hallmark of aging and has been linked to age-related diseases. Age-related macular degeneration (AMD), the most common aging-related retinal disease, is prospectively associated with retinal pigment epithelial (RPE)
Externí odkaz:
https://doaj.org/article/27a1cb1ccb6a4592ab522d2a9e8621a0
Autor:
Yan Li, Lingpeng Zhu, Meng-Xia Cai, Zi-Li Wang, Miao Zhuang, Cheng-Ye Tan, Tian-Hua Xie, Yong Yao, Ting-Ting Wei
Publikováno v:
Cell Death and Disease, Vol 14, Iss 9, Pp 1-16 (2023)
Abstract Diabetic retinopathy (DR) is a serious and relatively under-recognized complication of diabetes. Müller glial cells extend throughout the retina and play vital roles in maintaining retinal homeostasis. Previous studies have demonstrated tha
Externí odkaz:
https://doaj.org/article/80004ac294c942ba99cef6450781090d
Autor:
Yaling Hu, Bo Zhang, Peihua Lu, Jingying Wang, Cheng Chen, Ying Yin, Quan Wan, Jingjing Wang, Jiantong Jiao, Xiangming Fang, Zhening Pu, Lingli Gong, Li Ji, Lingpeng Zhu, Rui Zhang, Jia Zhang, Xusheng Yang, Qing Wang, Zhaohui Huang, Jian Zou
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 9, Pp n/a-n/a (2022)
Abstract Background NF‐κB signaling is widely linked to the pathogenesis and treatment resistance in cancers. Increasing attention has been paid to its anti‐oncogenic roles, due to its key functions in cellular senescence and the senescence‐as
Externí odkaz:
https://doaj.org/article/1878f5f2a8304ded8aac5a572702bc6d
Autor:
Yuhui Chai, Yawen Cai, Yu Fu, Yingdi Wang, Yiming Zhang, Xue Zhang, Lingpeng Zhu, Mingxing Miao, Tianhua Yan
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Depression is a common and serious mental disorder. Data on its pathogenesis remain unclear and the options of drug treatments are limited. Here, we explored the role of pyroptosis, a novel pro-inflammatory programmed cell death process, in depressio
Externí odkaz:
https://doaj.org/article/6cc328a3c52149b49cbd6f6ea8786680
Autor:
Meng-Yuan Zhang, Lingpeng Zhu, Xinhua Zheng, Tian-Hua Xie, Wenjuan Wang, Jian Zou, Yan Li, Hong-Ying Li, Jiping Cai, Shun Gu, Yong Yao, Ting-Ting Wei
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
Background: Diabetic retinopathy (DR) is one of the most important microvascular diseases of diabetes. Our previous research demonstrated that bile acid G-protein-coupled membrane receptor (TGR5), a novel cell membrane receptor of bile acid, ameliora
Externí odkaz:
https://doaj.org/article/b83b708e62594f6082a52e0dee6e4ef7
Autor:
Yawen Cai, Yuhui Chai, Yu Fu, Yingdi Wang, Yiming Zhang, Xue Zhang, Lingpeng Zhu, Mingxing Miao, Tianhua Yan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2022)
Amyloid β-protein (Aβ) is reported to activate NLRP3 inflammasomes and drive pyroptosis, which is subsequently involved in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease (AD). To date, the pathogenesis of AD is unfortun
Externí odkaz:
https://doaj.org/article/23e276e4c0ef4392981df875f13f8073
Autor:
Yan Li, Hong-Ying Li, Jun Shao, Lingpeng Zhu, Tian-Hua Xie, Jiping Cai, Wenjuan Wang, Meng-Xia Cai, Zi-Li Wang, Yong Yao, Ting-Ting Wei
Publikováno v:
Biomolecules, Vol 12, Iss 12, p 1778 (2022)
Endoplasmic reticulum (ER) and mitochondrial dysfunction play fundamental roles in the pathogenesis of diabetic retinopathy (DR). However, the interrelationship between the ER and mitochondria are poorly understood in DR. Here, we established high gl
Externí odkaz:
https://doaj.org/article/3ac715e5d91143f5978816b568c50b9f
Autor:
Yan Li, Hong-Ying Li, Jun Shao, Lingpeng Zhu, Tian-Hua Xie, Jiping Cai, Wenjuan Wang, Meng-Xia Cai, Zi-Li Wang, Yong Yao, Ting-Ting Wei
Background Endoplasmic reticulum (ER) and mitochondrial dysfunction play fundamental roles in the pathogenesis of diabetic retinopathy (DR). The communication between the mitochondria and the ER is mediated by a functional subdomain referred to as th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fe806e0bce5c443b65fade3e93e83c7
https://doi.org/10.21203/rs.3.rs-2093332/v1
https://doi.org/10.21203/rs.3.rs-2093332/v1
Publikováno v:
Aging (Albany NY)
Parkinson's disease (PD) is a common age-related neurodegenerative movement disorder, which is mainly due to the loss of dopaminergic neurons. Pyroptosis is a new programmed cell death characterized by NLR Family Pyrin Domain Containing 3 (NLRP3)-dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57be32aeb6fad01ba9ba9887e2b751e4
https://doi.org/10.18632/aging.103215
https://doi.org/10.18632/aging.103215
Autor:
Wenjuan Wang, Jian Zou, Youai Dai, Tianhua Xie, Xiaolu Wang, Zhong-Yuan Wang, Miao Zhuang, Yong Yao, Jianxin Tan, Chenyou Shen, Xiaowei Nie, Xusheng Yang, Lingpeng Zhu, Ting-Ting Wei, Shun Gu, Meng-Yuan Zhang
Publikováno v:
The FASEB Journal. 34:4189-4203
Background: Diabetic retinopathy is a common microvascular complication of diabetes mellitus. Abnormal energy metabolism in microvascular endothelium is involved in the progression of diabetic retinopathy. Bile Acid G-Protein-Coupled Membrane Recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::375735820ec713b3282f2b3cbb931b61
https://doi.org/10.1096/fj.201902496rr
https://doi.org/10.1096/fj.201902496rr