Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lingna Zhou"'
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-8 (2024)
Abstract Background Traditional biochemical screening for neonatal inherited metabolic diseases has high false-positive rates and low positive predictive values, which are not conducive to early diagnosis and increase parents’ anxiety. This study a
Externí odkaz:
https://doaj.org/article/c5e6942b41274d50a2538078d7614095
Publikováno v:
BMC Pediatrics, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract Objective To examine the clinical application of genomic screening in newborns small for gestational age (SGA), hoping to provide an efficient technique for early discovery of neonatal diseases, which is necessary to elevate survival rates a
Externí odkaz:
https://doaj.org/article/f2e02cc1f5654f55acbca3342ca48a74
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-8 (2021)
Abstract Objective To explore the clinical application of NeoSeq in newborn screening. Methods Based on the results obtained from traditional newborn screening (NBS) with tandem mass spectrometry (TMS), three cohorts were recruited into the present s
Externí odkaz:
https://doaj.org/article/b776e72405dd47229ceb29b5e2480efc
Autor:
Yuqi Gong, PhD, Lingna Zhou, MD, Liya Ding, MD, Jing Zhao, MD, Zhe Wang, PhD, Guoping Ren, PhD, Jing Zhang, PhD, Zhengrong Mao, PhD, Ren Zhou, PhD
Publikováno v:
Medicine, Vol 101, Iss 24, p e29312 (2022)
Abstract. Diffuse Large B Cell Lymphoma (DLBCL), the most common form of blood cancer. The genetic and clinical heterogeneity of DLBCL poses a major barrier to diagnosis and treatment. Hence, we aim to identify potential biomarkers for DLBCL. Differe
Externí odkaz:
https://doaj.org/article/a812ca7c8a664118ae78ec8240657c94
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
ObjectivesTo understand the knowledge, attitude, willingness, and ability of healthcare professionals working in newborn screening (NBS) centers regarding newborn genetic screening (nGS).MethodsThe questionnaire consisted of four sections with 27 que
Externí odkaz:
https://doaj.org/article/2997bf7a079d44a5b2d17a70a75ef397
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
ObjectiveTo evaluate the effectiveness of non-invasive prenatal screening (NIPS) in prenatal screening of fetal pathogenic copy number variants (CNVs).Materials and MethodsWe evaluated the prenatal screening capacity using traditional and retrospecti
Externí odkaz:
https://doaj.org/article/ff2c0bbc777f432aafba60b2d1a5fde8
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
ObjectiveTo evaluate the accuracy of Z-scores of noninvasive prenatal screening (NIPS) in predicting 21, 18 trisomy, and X chromosome aneuploidy.MethodsA total of 39,310 prenatal women were recruited for NIPS from September 2015 to September 2020. In
Externí odkaz:
https://doaj.org/article/a58e3d66280c4b87b760a7f5c3165bb6
Autor:
Lingna Zhou, Liya Ding, Yuqi Gong, Jing Zhao, Jing Zhang, Zhengrong Mao, Zhe Wang, Wei Zhang, Ren Zhou
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Diffuse large B-cell lymphoma (DLBCL) is the most frequent and commonly diagnosed subtype of NHL, which is characterized by high heterogeneity and malignancy, and most DLBCL patients are at advanced stages. The serine/threonine kinase NEK2 (NIMA-rela
Externí odkaz:
https://doaj.org/article/64cbb22780874115aa196c23f95a348b
Publikováno v:
PeerJ, Vol 8, p e10269 (2020)
Background Host response diffuse large B-cell lymphoma (HR DLBCL) shares features of histologically defined T-cell/histiocyte-rich B-cell lymphoma, including fewer genetic abnormalities, frequent splenic and bone marrow involvement, and younger age a
Externí odkaz:
https://doaj.org/article/a2d7f3e75d77482e9c484c85bdb65e09
Publikováno v:
International Journal of Endocrinology, Vol 2020 (2020)
Purpose. Mutations and phenotypic characteristics remain unclear in patients with congenital hypothyroidism (CH), and no study concerning whether the outcome of transient CH (TCH) or permanent CH (PCH) is determined by mutations has been reported. Me
Externí odkaz:
https://doaj.org/article/12be35a3c38e4739b887f87620072469