Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Lingling Xuan"'
Autor:
Chang Liu, Kun Chen, Fei Zhao, Lingling Xuan, Yuting Wang, Chungui Xu, Zhiyuan Wu, Dongmei Wang, Chunfeng Qu
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Some occult hepatitis B virus (HBV) infections are resulted from PreS mutations that reduce secretion of envelope protein (HBsAg). We investigated the ceramide amounts and species in hepatocytes infected with PreS variants that we
Externí odkaz:
https://doaj.org/article/cac44fb3209e4d7697f637aa8a8dffad
Autor:
Lingling Xuan, Feifei Han, Lili Gong, Yali Lv, Zirui Wan, He Liu, Lulu Ren, Song Yang, Wen Zhang, Ting Li, Chunting Tan, Lihong Liu
Publikováno v:
Lipids in Health and Disease, Vol 19, Iss 1, Pp 1-9 (2020)
Abstract Background Ceramide, a bioactive lipid, plays an essential role in the development of several pulmonary inflammatory diseases. Matrix metallopeptidase 9 (MMP-9) regulates the synthesis and degradation of extracellular matrix, and is associat
Externí odkaz:
https://doaj.org/article/c8becc15318545f4a4dee3cd91bfdb2c
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Anlotinib (ANL) shows promising efficacy in patients with renal cell cancer (RCC). Here, for the first time, a serum eicosanoid metabolomics profile and pharmacodynamics in Renca syngeneic mice treated with ANL was performed and integrated using our
Externí odkaz:
https://doaj.org/article/c03b53275dd44489ac5ac3a381bdd006
Autor:
Song Yang, Ting Hu, He Liu, Ya-li Lv, Wen Zhang, Han Li, Lingling Xuan, Li-li Gong, Li-hong Liu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 138, Iss , Pp 111441- (2021)
Metabolic syndrome (MetS) is a complex, multifactorial disease which lead to an increased risk of cardiovascular disease, type 2 diabetes, and stroke. However, selective, and potent drugs for the treatment of MetS are still lacking. Previous studies
Externí odkaz:
https://doaj.org/article/5ec5e42f56174a5fab01669d58f61709
Autor:
Lingling Xuan, Feifei Han, Lili Gong, Yali Lv, Zirui Wan, He Liu, Dongsu Zhang, Yangjie Jia, Song Yang, Lulu Ren, Lihong Liu
Publikováno v:
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-8 (2018)
Abstract Background Metabolic syndrome is a common extrapulmonary comorbidity in patients with chronic obstructive pulmonary disease (COPD). However, the reported relationship of COPD with dyslipidemia, an important component of metabolic syndrome, i
Externí odkaz:
https://doaj.org/article/dd4054db1cfc40fd9f81f00153d4185e
Autor:
Changtao Li, Lingling Xuan, Yuming He, Jie Wang, Hui Zhang, Yeqing Ying, Aimin Wu, Antony Bacic, Wei Zeng, Lili Song
Publikováno v:
Polymers, Vol 11, Iss 1, p 38 (2018)
A bamboo shoot is the immature stem of the woody grass and a nutritious and popular vegetable in East Asia. However, it undergoes a rapid xylogenesis process right after harvest, even being stored in a cold chamber. To investigate the molecular regul
Externí odkaz:
https://doaj.org/article/207107c36cd847178d62aabab013d36e
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Background: Chronic inflammation is one of the important mediators of colitis-related colon cancer (CRC). Abundant mast cells (MCs) were observed in the tumor microenvironment and mediators released upon MC activation play an important role in the pr
Externí odkaz:
https://doaj.org/article/aa5a0242796b4c93a9fd97597ff54df0
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147380 (2016)
BACKGROUND:Histone deacetylase 2 (HDAC2) is a class I histone deacetylase family member that plays a critical role in suppressing inflammatory gene expression in the airways, lung parenchyma, and alveolar macrophages in patients with chronic obstruct
Externí odkaz:
https://doaj.org/article/626a52b2926a47abbea499bb68261987
Autor:
Lijian Tao, Zhongjun Li, Renna Luo, Gaoyun Hu, Qi Hou, Zhiqi Lao, Lingling Xuan, Jinye Bai, Xiangbao Meng, Qinghua Lou
Publikováno v:
Molecules, Vol 17, Iss 1, Pp 884-896 (2012)
Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones modified w
Externí odkaz:
https://doaj.org/article/31f4ec9d74564042bf329c2b19e35c83
Publikováno v:
Crystal Growth & Design. 22:2407-2416
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb884d4801d815b491702845bd633f21
https://doi.org/10.1021/acs.cgd.1c01481
https://doi.org/10.1021/acs.cgd.1c01481