Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Lingli Liang"'
Autor:
Siyi Liu, Shuting Yang, Xuan Zhu, Xiang Li, Xi Zhang, Xiaoqiong Zhou, Hong Cheng, Fu-Quan Huo, Qingxiang Mao, Lingli Liang
Publikováno v:
Biology Direct, Vol 18, Iss 1, Pp 1-15 (2023)
Abstract Introduction Inflammation and nerve injury promote astrocyte activation, which regulates the development and resolution of pain, in the spinal dorsal horn. APOE regulates lipid metabolism and is predominantly expressed in the astrocytes. How
Externí odkaz:
https://doaj.org/article/a78f40c3d3b8464ba444aeaa19dcb060
Autor:
Huahua Liu, Rui Zhou, Shanshan Li, Jinling Dong, Yuan Fang, Yuru Luo, Hongyu Su, Baochang Lai, Lingli Liang, Donghong Zhang, Yanmin Zhang, John Y-J. Shyy, Bin Zhou, Zuyi Yuan, Yidong Wang
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108722- (2024)
Summary: Epigenetic regulation of heart development remains incompletely understood. Here we show that LSD1, a histone demethylase, plays a crucial role in regulating cardiomyocyte proliferation during heart development. Cardiomyocyte-specific deleti
Externí odkaz:
https://doaj.org/article/ed296fea56c44464b7407d08e4463311
Autor:
Qingxiang Mao, Lixia Tian, Jianxiong Wei, Xiaoqiong Zhou, Hong Cheng, Xuan Zhu, Xiang Li, Zihao Gao, Xi Zhang, Lingli Liang
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
The microtubule-stabilizing drug paclitaxel (PTX) is a chemotherapeutic agent widely prescribed for the treatment of various tumor types. The main adverse effect of PTX-mediated therapy is chemotherapy-induced peripheral neuropathy (CIPN) and neuropa
Externí odkaz:
https://doaj.org/article/348ff7f76115421dad66d98a3298a3f6
Autor:
Shibin Du, Shaogen Wu, Xiaozhou Feng, Bing Wang, Shangzhou Xia, Lingli Liang, Li Zhang, Gokulapriya Govindarajalu, Alexander Bunk, Feni Kadakia, Qingxiang Mao, Xinying Guo, Hui Zhao, Tolga Berkman, Tong Liu, Hong Li, Jordan Stillman, Alex Bekker, Steve Davidson, Yuan-Xiang Tao
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 13 (2022)
Maladaptive changes of nerve injury–associated genes in dorsal root ganglia (DRGs) are critical for neuropathic pain genesis. Emerging evidence supports the role of long noncoding RNAs (lncRNAs) in regulating gene transcription. Here we identified
Externí odkaz:
https://doaj.org/article/ded5119d50a34abebc17aa844440c919
Autor:
Bo Xu, Jing Cao, Jun Zhang, Shushan Jia, Shaogen Wu, Kai Mo, Guihua Wei, Lingli Liang, Xuerong Miao, Alex Bekker, Yuan-Xiang Tao
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Externí odkaz:
https://doaj.org/article/9ce65bd4949c4c968b98a90f7fb4b293
Autor:
Jian-Yuan Zhao, Lingli Liang, Xiyao Gu, Zhisong Li, Shaogen Wu, Linlin Sun, Fidelis E. Atianjoh, Jian Feng, Kai Mo, Shushan Jia, Brianna Marie Lutz, Alex Bekker, Eric J. Nestler, Yuan-Xiang Tao
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Transcriptional changes occur in the dorsal root ganglion in response to nerve injury and may contribute to neuropathic pain. Here the authors show that the DNA methyltransferase DNMT3a is upregulated in rodents following nerve injury, and may contri
Externí odkaz:
https://doaj.org/article/6546e90f8d0a479b8916bd70184ce7f5
Autor:
Jian-Yuan Zhao, Lingli Liang, Xiyao Gu, Zhisong Li, Shaogen Wu, Linlin Sun, Fidelis E. Atianjoh, Jian Feng, Kai Mo, Shushan Jia, Brianna Marie Lutz, Alex Bekker, Eric J. Nestler, Yuan-Xiang Tao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/f74e78ba0bf244d181d9ef5ebf67ae24
Autor:
Bo Xu, Jing Cao, Jun Zhang, Shushan Jia, Shaogen Wu, Kai Mo, Guihua Wei, Lingli Liang, Xuerong Miao, Alex Bekker, Yuan-Xiang Tao
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Peripheral nerve injury increased the expression of the DNA methyltransferase 3A (Dnmt3a) mRNA and its encoding Dnmt3a protein in injured dorsal root ganglia (DRG). This increase is considered as an endogenous instigator in neuropathic pain genesis t
Externí odkaz:
https://doaj.org/article/e02c2913179d49c09e32008d24e49d4f
Autor:
Lingli Liang, Yanjun Chen, Chunyan Wu, Zitong Cao, Linzhen Xia, Jun Meng, Lu He, Chunfen Yang, Zuo Wang
Publikováno v:
Journal of Assisted Reproduction and Genetics. 40:3-17
The placenta is essential for a successful pregnancy and healthy intrauterine development in mammals. During human pregnancy, the growth and development of the placenta are inseparable from the rapid proliferation, invasion, and migration of trophobl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db5caf590351b8d51e6ea09a2d178f5b
https://doi.org/10.1007/s10815-022-02677-9
https://doi.org/10.1007/s10815-022-02677-9
Publikováno v:
DNA and Cell Biology. 41:824-837
Atherosclerosis is a complex vascular inflammatory disease in which multiple cell types are involved, including vascular smooth muscle cells (VSMCs). In response to vascular injury and inflammatory stimuli, VSMCs undergo a "phenotypic switching" char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7eda50d83a6c2c82b39d9a95fd2b95c
https://doi.org/10.1089/dna.2022.0278
https://doi.org/10.1089/dna.2022.0278