Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Lingli, Kong"'
Autor:
Lingli Kong, Jianfang Liu, Meng Zhang, Zhuoyang Lu, Han Xue, Amy Ren, Jiankang Liu, Jinping Li, Wai Li Ling, Gang Ren
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Although structures of vitrified supramolecular complexes have been determined at near-atomic resolution, elucidating in situ molecular structure in living cells remains a challenge. Here, we report a straightforward liquid cell technique, o
Externí odkaz:
https://doaj.org/article/6a023bb9345648ad98732d280a7daaed
Publikováno v:
Pharmacological Research, Vol 195, Iss , Pp 106893- (2023)
Depression is a highly prevalent disorder of the central nervous system. The neuropsychiatric symptoms of clinical depression are persistent and include fatigue, anorexia, weight loss, altered sleep patterns, hyperalgesia, melancholia, anxiety, and i
Externí odkaz:
https://doaj.org/article/c39308bbe62043929b6fa29b249cb696
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The ionization edges encoded in the electron energy loss spectroscopy (EELS) spectra enable advanced material analysis including composition analyses and elemental quantifications. The development of the parallel EELS instrument and fast, se
Externí odkaz:
https://doaj.org/article/43b679415f1547318b51e62e1fea6455
Autor:
Lingli Kong, Chao Sui, Tian Chen, Lei Zhang, Wei Zhao, Yi Zheng, Bingyu Liu, Xiaochen Cheng, Chengjiang Gao
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112306- (2023)
Summary: STING is an endoplasmic reticulum-resident protein regulating innate immunity. After binding with cyclic guanosine monophosphate-AMP (cGAMP), STING translocates from the endoplasmic reticulum (ER) to the Golgi apparatus to stimulate TBK1 and
Externí odkaz:
https://doaj.org/article/eca767a74d51420ea0b37f179187f5f4
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
ObjectiveBrain-derived neurotrophic factor (BDNF) has not been validated as a diagnostic marker for Alzheimer's disease (AD). To provide a different perspective, this study aimed to evaluate the relationship between serum levels of mature BDNF (mBDNF
Externí odkaz:
https://doaj.org/article/dfa7c237c72548918bd74121649f4887
Akademický článek
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Autor:
Xueer Wang, Honghai Zhang, Zhugui Shao, Wanxin Zhuang, Chao Sui, Feng Liu, Xiaorong Chen, Jinxiu Hou, Lingli Kong, Hansen Liu, Yi Zheng, Bingyu Liu, Tian Chen, Lei Zhang, Xinming Jia, Chengjiang Gao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-15 (2021)
Abstract Spleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase, which plays an essential role in both innate and adaptive immunity. However, the key molecular mechanisms that regulate SYK activity are poorly understood. Here we identified th
Externí odkaz:
https://doaj.org/article/008986a702e944bcb5512dcc2ce2362c
Publikováno v:
Journal of Biological Research - Thessaloniki, Vol 28, Iss 1, Pp 1-11 (2021)
Abstract Background Circ_0000396 was found to be down-regulated in the rheumatoid arthritis (RA) patients and had a high diagnostic value. However, the function and mechanisms underlying circ_0000396 in RA progression remain unclear. Methods The expr
Externí odkaz:
https://doaj.org/article/6fa6ae5ee36a4e46916e73031231ed8a
Autor:
Lingli Kong, Yixing Lu, Liuye Yang, Wanying Zhang, Beini Zuo, Xianfeng Peng, Zonghua Qin, Miao Li, Zhenling Zeng, Dongping Zeng
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Plasmid-borne colistin resistance mediated by mcr-1 is a growing problem, which poses a serious challenge to the clinical application of colistin for Gram-negative bacterial infections. Drug combination is one of the effective strategies to treat col
Externí odkaz:
https://doaj.org/article/253ac7fc880b46b18e81ba2c4ca84a66
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 48, Iss 1, Pp 969-976 (2020)
Rheumatoid arthritis (RA) is a chronic joint inflammatory disease that is closely associated with dysregulation of fibroblast-like synoviocytes (FLSs). Protocatechuic acid (PCA), a phenolic compound of anthocyanins, has been proven to possess anti-in
Externí odkaz:
https://doaj.org/article/cf05839604844a29b3d401035fb3a840