Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Linghui, Zeng"'
Publikováno v:
Pharmaceutical Biology, Vol 62, Iss 1, Pp 195-206 (2024)
Context Cephaeline is a natural product isolated from ipecac (Cephaelis ipecacuanha [Brot.] A. Rich. [Rubiaceae]). It exhibits promising anti-lung cancer activity and ferroptosis induction may be a key mechanism for its anti-lung cancer effect.Object
Externí odkaz:
https://doaj.org/article/9344319bee344dabbb8fdf461e93a930
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-30 (2024)
Abstract Herpes simplex virus (HSV), an epidemic human pathogen threatening global public health, gains notoriety for its complex pathogenesis that encompasses lytic infection of mucosal cells, latent infection within neurons, and periodic reactivati
Externí odkaz:
https://doaj.org/article/a3ef89d5859542f3b4cda5353a6bf5b6
Autor:
Tongli Chen, Yan Dai, Chenghao Hu, Zihao Lin, Shengzhe Wang, Jing Yang, Linghui Zeng, Shanshan Li, Weiyun Li
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-28 (2024)
Abstract Background Maintaining the structural and functional integrity of the blood–brain barrier (BBB) is vital for neuronal equilibrium and optimal brain function. Disruptions to BBB performance are implicated in the pathology of neurodegenerati
Externí odkaz:
https://doaj.org/article/0564e56b7d1e4ec4a686386fc85b92a1
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Cigarette smoke (CS) exposure is known to cause injury to respiratory tract epithelial cells and is a contributing factor in the development of chronic obstructive pulmonary disease and lung cancer. Electronic cigarettes (e-cigarettes) are g
Externí odkaz:
https://doaj.org/article/1218310da573492b9d4b5b673e5d35a2
Publikováno v:
Defence Technology, Vol 31, Iss , Pp 484-495 (2024)
The study of non-axisymmetric fuel dispersal and detonation can provide reference for the prevention of industrial cloud explosion accidents and the design of fuel air explosive (FAE). The concentration and detonation fields of 85 kg cylindrical and
Externí odkaz:
https://doaj.org/article/110c5364567a4b4dbcfef80eb96f8054
ARIH1 activates STING-mediated T-cell activation and sensitizes tumors to immune checkpoint blockade
Autor:
Xiaolan Liu, Xufeng Cen, Ronghai Wu, Ziyan Chen, Yanqi Xie, Fengqi Wang, Bing Shan, Linghui Zeng, Jichun Zhou, Bojian Xie, Yangjun Cai, Jinyan Huang, Yingjiqiong Liang, Youqian Wu, Chao Zhang, Dongrui Wang, Hongguang Xia
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Despite advances in cancer treatment, immune checkpoint blockade (ICB) only achieves complete response in some patients, illustrating the need to identify resistance mechanisms. Using an ICB-insensitive tumor model, here we discover cisplati
Externí odkaz:
https://doaj.org/article/339be2dc00684f1c8b1d44ed1c9aad8f
Publikováno v:
Research, Vol 7 (2024)
Golgi protein 73 (GP73), a resident protein of the Golgi apparatus, is notably elevated in hepatocellular carcinoma (HCC). While its critical role in remodeling the tumor microenvironment (TME) is recognized, the intricate mechanisms are not fully un
Externí odkaz:
https://doaj.org/article/5a93b51a82c64c8685fe02d47f4fccef
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Two-dimensional (2D) nanomaterials, such as graphene, black phosphorus and transition metal dichalcogenides, have attracted increasing attention in biology and biomedicine. Their high mechanical stiffness, excellent electrical conductivity,
Externí odkaz:
https://doaj.org/article/edb1f11f58c640f8a25c29cd99b1b570
Publikováno v:
Green Synthesis and Catalysis, Vol 4, Iss 2, Pp 160-168 (2023)
Disclosed herein is a novel Rh/Ag co-catalyzed SNH directed C–H activation and C–H/N–H bond functionalization protocol of free NH-sulfoximines with hypervalent iodonium ylides. With the aid of AgOTf, these C–H functionalization/cyclization
Externí odkaz:
https://doaj.org/article/fee1c9e62b8e45788ad8352ac5620074
Autor:
Chen Chen, Tao Zhu, Lifen Gong, Zhe Hu, Hao Wei, Jianchen Fan, Donghui Lin, Xiaojun Wang, Junyu Xu, Xinyan Dong, Yifan Wang, Ningxiao Xia, Linghui Zeng, Peifang Jiang, Yicheng Xie
Publikováno v:
Neurobiology of Disease, Vol 186, Iss , Pp 106273- (2023)
Epilepsy is one of the most common neurological disorders. Neuroinflammation involving the activation of microglia and astrocytes constitutes an important and common mechanism in epileptogenesis. Transient receptor potential melastatin 2 (TRPM2) is a
Externí odkaz:
https://doaj.org/article/98754b13d1ac4fd9bea6deb83c1bc203