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Discovery of biomarkers for depressed patients and evaluation of Xiaoyaosan efficacy based on liquid chromatography-mass spectrometry.

Autor: Linghu, Ting^1,2 (AUTHOR), Liu, Caichun^1,2 (AUTHOR), Wang, Qi^1,2 (AUTHOR), Tian, Junsheng^1,2 (AUTHOR), Qin, Xuemei^1,2 (AUTHOR)

Publikováno v: Journal of Liquid Chromatography & Related Technologies. 2021, Vol. 44 Issue 11/12, p538-549. 12p. 2 Diagrams, 3 Charts, 5 Graphs.

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Discovery of biomarkers for depressed patients and evaluation of Xiaoyaosan efficacy based on liquid chromatography-mass spectrometry

Autor: Xue-Mei Qin, Jun-Sheng Tian, Cai-chun Liu, Linghu Ting, Qi Wang

Publikováno v: Journal of Liquid Chromatography & Related Technologies. 44:538-549

Depression, a serious mental illness, affects a considerable proportion of people to suffer greatly and function poorly in everyday life. Xiaoyaosan, as a well-known Chinese formula, has been widel...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1ee21647963a0a209574355617a5e3ce
https://doi.org/10.1080/10826076.2021.1975294

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Comprehensive Analysis Strategy of Nervous–Endocrine–Immune-Related Metabolites to Evaluate Arachidonic Acid as a Novel Diagnostic Biomarker in Depression

Autor: Xue-Mei Qin, Yao Gao, Xiao Li, Linghu Ting, Hui-Liang Zhao, Jun-Sheng Tian, Yu-Zhi Zhou

Publikováno v: Journal of Proteome Research. 20:2477-2486

Depression is one of the most complex multifactorial diseases affected by genetic and environmental factors. The molecular mechanism underlying depression remains largely unclear. To address this issue, a novel nervous-endocrine-immune (NEI) network

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a555c87ced46a7fe33fa8e0469ac4f
https://doi.org/10.1021/acs.jproteome.0c00940

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Stable Isotope-Resolved Metabolomics Studies on Corticosteroid-Induced PC12 Cells: A Strategy for Evaluating Glucose Catabolism in an in Vitro Model of Depression

Autor: Xue-Mei Qin, Linghu Ting, Yao Gao, Shao-Bo Liu, Jun-Sheng Tian, Yun-Hao Zhao, Wen-Ze Wu

Publikováno v: Journal of proteome research. 21(3)

Depression is a common psychopathological state or mood disorder syndrome. The serious risks to human life and the inadequacy of the existing antidepressant drugs have driven us to understand the pathogenesis of depression from a new perspective. Our

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5898b10eeffe537e891b1e7196ad7343
https://pubmed.ncbi.nlm.nih.gov/34699232

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Stable Isotope-Resolved Metabolomics Reveals the Abnormal Brain Glucose Catabolism in Depression Based on Chronic Unpredictable Mild Stress Rats

Autor: Linghu Ting, Jun-Sheng Tian, Xue-Mei Qin, Shao-Bo Liu, Yao Gao, Yumei Han

Publikováno v: Journal of proteome research. 20(7)

The severe harm of depression to human life has attracted great attention to neurologists, but its pathogenesis is extremely complicated and has not yet been fully elaborated. Here, we provided a new strategy for revealing the specific pathways of ab

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7a8b2a8021d655e4426242496b04ce
https://pubmed.ncbi.nlm.nih.gov/34077228

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Metabolomic analysis of the hippocampus in a rat model of chronic mild unpredictable stress-induced depression based on a pathway crosstalk and network module approach

Autor: Linghu Ting, Junfang Mu, Teng Xu, Yao Gao, Jun-Sheng Tian, Xue-Mei Qin, Hui-Liang Zhao

Publikováno v: Journal of pharmaceutical and biomedical analysis. 193

Background The molecular alterations underlying the pathogenesis of depression have not been systematically defined. Increasing evidence suggests that hippocampus metabolism is strongly involved in the pathogenesis of chronic mild unpredictable stres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93169cd9ff70523f426b3d87dde7217b
https://pubmed.ncbi.nlm.nih.gov/33190083

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