Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lingfei Kon"'
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Abstract Background As a significant cause of cancer deaths worldwide, breast cancer continues to be a troublesome malignancy. Long non-coding RNAs (lncRNAs) have been implicated in the development of breast cancer. Abnormal methylation has been asso
Externí odkaz:
https://doaj.org/article/4746a6baf25b4aebaf66f251775f1783
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-13 (2021)
Journal of Translational Medicine
Journal of Translational Medicine
Background As a significant cause of cancer deaths worldwide, breast cancer continues to be a troublesome malignancy. Long non-coding RNAs (lncRNAs) have been implicated in the development of breast cancer. Abnormal methylation has been associated wi
Autor:
Ye Yuan, Lei Chen, Kexu Song, Miaomiao Cheng, Ling Fang, Lingfei Kong, Lanlan Yu, Ruonan Wang, Zhendong Fu, Minmin Sun, Qian Wang, Chengjun Cui, Haojue Wang, Jiuyang He, Xiaonan Wang, Yuan Liu, Bing Jiang, Jing Jiang, Chenxuan Wang, Xiyun Yan, Xinzheng Zhang, Lizeng Gao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Natural antimicrobial peptides (AMPs) and enzymes (AMEs) are promising non-antibiotic candidates against antimicrobial resistance but suffer from low efficiency and poor stability. Here, we develop peptide nanozymes which mimic the mode of a
Externí odkaz:
https://doaj.org/article/92ddb5981cd24293988a6db4ab218f15
Autor:
Yinhui Qin, Zhen Li, Xianwei Zhang, Junjun Li, Yuetai Teng, Na Zhang, Shengyu Zhao, Lingfei Kong, Weihong Niu
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36819- (2024)
The partner of NOB1 homolog (PNO1) is an RNA-binding protein that participates in ribosome biogenesis and protein modification. The functions of this molecule are largely unknown in cancers, particularly breast cancer. We employed bioinformatics meth
Externí odkaz:
https://doaj.org/article/d95b5c37baf742aab7c7d00115441f9e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Metformin shows promise in breast cancer prevention, but its underlying mechanisms remain unclear. This study investigated the impact of metformin on the repopulation dynamics of mammary epithelial cells (MECs) and the signaling pathways in non-tumor
Externí odkaz:
https://doaj.org/article/8f6cdf42f98b410f88f584c1a4336ebf
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e31778- (2024)
Core 1 β 1,3-galactosyltransferase 1 (C1GALT1) acts as an important glycosyltransferase in the occurrence and development of tumor glycosylation. However, the regulatory mechanisms of C1GALT1 in thyroid cancer (TC) is still unclear. In this study, w
Externí odkaz:
https://doaj.org/article/b34eb8e0ec634d499a268100c6687b0f
Autor:
Yanwu Huo, Lingfei Kong, Ye Zhang, Min Xiao, Kang Du, Sunyuntao Xu, Xiaoxue Yan, Jun Ma, Taotao Wei
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract The Gabija system is a newly discovered bacterial immune system that consists of GajA and GajB. Here we report the cryo-EM structure of the Gabija complex from Bacillus cereus VD045 at 3.6 Å, which provides the direct evidence of interactio
Externí odkaz:
https://doaj.org/article/a020326c290044238a7b87e42a67e75d
Autor:
Ye Yuan, Lei Chen, Lingfei Kong, Lingling Qiu, Zhendong Fu, Minmin Sun, Yuan Liu, Miaomiao Cheng, Saiyu Ma, Xiaonan Wang, Changhui Zhao, Jing Jiang, Xinzheng Zhang, Liping Wang, Lizeng Gao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Amyloid-like assembly is not only associated with pathological events, but also leads to the development of novel nanomaterials with unique properties. Herein, using Fmoc diphenylalanine peptide (Fmoc–F–F) as a minimalistic model, we fou
Externí odkaz:
https://doaj.org/article/5ec1a6ff13bb4a5d9a49f8f142acbd34
Autor:
Guanzheng Liu, Chaojie Bu, Guangzhong Guo, Zhiyue Zhang, Zhiyuan Sheng, Kaiyuan Deng, Shuang Wu, Sensen Xu, Yage Bu, Yushuai Gao, Meiyun Wang, Gang Liu, Lingfei Kong, Tianxiao Li, Ming Li, Xingyao Bu
Publikováno v:
Cancer Medicine, Vol 12, Iss 16, Pp 17171-17183 (2023)
Abstract Background Oligodendroglioma is known for its relatively better prognosis and responsiveness to radiotherapy and chemotherapy. However, little is known about the evolution of genetic changes as oligodendroglioma progresses. Methods In this s
Externí odkaz:
https://doaj.org/article/20b92653a3c04fca84294e5f2f3f310e
Autor:
Yameng Zhang, Shaokang Peng, Zhihua Xue, Guohua Zhao, Qing Li, Zhiyuan Zhu, Yufei Gao, Lingfei Kong, for the Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
PeerJ Computer Science, Vol 9, p e1706 (2023)
Alzheimer’s disease (AD) is an irreversible neurodegenerative disease with a high prevalence in the elderly population over 65 years of age. Intervention in the early stages of AD is of great significance to alleviate the symptoms. Recent advances
Externí odkaz:
https://doaj.org/article/7ae0b07a55fc479183477e0eb1d01b61