Zobrazeno 1 - 10
of 329
pro vyhledávání: '"Lingdong, Kong"'
Autor:
Yuling He, Lingdong Kong, Xumeng Ji, Minglei Zhuo, Tongtong An, Bo Jia, Yujia Chi, Jingjing Wang, Jun Zhao, Jianjie Li, Xue Yang, Hanxiao Chen, Xiaoyu Zhai, Yidi Tai, Lu Ding, Ziping Wang, Yuyan Wang
Publikováno v:
Thoracic Cancer, Vol 15, Iss 23, Pp 1727-1738 (2024)
Abstract Background Usage of immune checkpoint inhibitors (ICIs) has prolonged the overall survival (OS) of patients with extensive‐stage small‐cell lung cancer (ES‐SCLC). In clinical trials, males accounted for a large proportion, leading to t
Externí odkaz:
https://doaj.org/article/3975d61caa304492891d0cdbf6aec28d
Autor:
Xue Liang, Kunpeng Liu, Xin Jia, Cuiqin Cheng, Meiqi Zhang, Lingdong Kong, Qiqi Li, Zhe Liu, Min Li, Junliang Li, Yao Wang, Anlong Xu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 8, Pp 3513-3527 (2024)
Bile acids (BAs) are natural metabolites in mammals and have the potential to function as drugs against viral infection. However, the limited understanding of chenodeoxycholic acid (CDCA) receptors and downstream signaling, along with its lower suppr
Externí odkaz:
https://doaj.org/article/b8181f6001e84516a09bc978280c253e
Autor:
Ying Zhang, Yaya Zhang, Junting Zhang, Tao Wang, Luhui Yi, Yao Zeng, Guorong Zeng, Lingdong Kong, Bo Ye, Yunmin Yi
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Purpose The main objective is to quantify the lens nuclear opacity using spectral-domain optical coherence tomography (SD-OCT) and to evaluate its association with Lens Opacities Classification System III (LOCS-III) system, lens thickness (L
Externí odkaz:
https://doaj.org/article/17a246e4a2434d478f35a95fe9c5c737
Autor:
Ziang Zhou, Yumeng Wang, Yu Xing, Shuman Pan, Wanru Wang, Jie Yang, Wenyuan Wu, Jie Zhou, Luyi Huang, Qiongdan Liang, Dongmei Zhang, Lingdong Kong
Publikováno v:
Pharmaceuticals, Vol 17, Iss 11, p 1416 (2024)
Background/Objectives: High fructose has been implicated as an important trigger of kidney inflammation in patients and experimental models. Magnolol, isolated from Magnolia officinalis, has an anti-inflammatory effect, but its protective role in pod
Externí odkaz:
https://doaj.org/article/eaac0c24b6004d669c00a9349af97812
Autor:
Jinyong Wang, Fang Xie, Xin Jia, Xuejiao Wang, Lingdong Kong, Yiying Li, Xue Liang, Meiqi Zhang, Yuting He, Wandi Feng, Tong Luo, Yao Wang, Anlong Xu
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 6, Pp 100972- (2024)
The stimulator of interferon genes (STING), an integral adaptor protein in the DNA-sensing pathway, plays a pivotal role in the innate immune response against infections. Additionally, it presents a valuable therapeutic target for infectious diseases
Externí odkaz:
https://doaj.org/article/5e69b58b7f6a4f7bab4ebf696321d452
Publikováno v:
PeerJ, Vol 12, p e17231 (2024)
Ageratina adenophora is an invasive weed species found in many countries. Methods to control the spread of this weed have been largely unsuccessful. Soil pH is the most important soil factor affecting the availability of nutrients for plant and impac
Externí odkaz:
https://doaj.org/article/89141ce5164a4eab981b9682cf0aceac
Autor:
Jiashu Yang, Chenyang Jiao, Nannan Liu, Wen Liu, Yueyao Wang, Ying Pan, Lingdong Kong, Wenjie Guo, Qiang Xu
Publikováno v:
Research, Vol 7 (2024)
The NLRP3 inflammasome plays a critical role in various inflammatory conditions. However, despite extensive research in targeted drug development for NLRP3, including MCC950, clinical success remains elusive. Here, we discovered that the activated NL
Externí odkaz:
https://doaj.org/article/663c1d53e9b34a22ab1bc3ac162b7dee
Autor:
Chuanfeng Tang, Qiaona Wang, Jingyan Shen, Congying Wang, Hong Ding, Shiyu Wen, Fan Yang, Ruiqing Jiao, Xingxin Wu, Jianmei Li, Lingdong Kong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 5, Pp 2017-2038 (2023)
Neurogenesis decline in hippocampal dentate gyrus (DG) participates in stress-induced depressive-like behaviors, but the underlying mechanism remains poorly understood. Here, we observed low-expression of NOD-like receptor family pyrin domain contain
Externí odkaz:
https://doaj.org/article/0ec31c9ba00740ee9e6f24b26d12a67b
Autor:
Yuyu Zhu, Zijun Ouyang, Haojie Du, Meijing Wang, Jiaojiao Wang, Haiyan Sun, Lingdong Kong, Qiang Xu, Hongyue Ma, Yang Sun
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 11, Pp 4011-4039 (2022)
Natural products, and especially the active ingredients found in traditional Chinese medicine (TCM), have a thousand-year-long history of clinical use and a strong theoretical basis in TCM. As such, traditional remedies provide shortcuts for the deve
Externí odkaz:
https://doaj.org/article/cd5d18c529c8496c9f2850ba8b1fb0c1
Publikováno v:
Pharmaceutics, Vol 14, Iss 10, p 2202 (2022)
Long-term high fructose intake drives oxidative stress, causing glomerular podocyte injury. Polydatin, isolated from Chinese herbal medicine Polygonum cuspidatum, is used as an antioxidant agent that protects kidney function. However, it remains uncl
Externí odkaz:
https://doaj.org/article/123de85ecec141f498b7ee4bdb3eedaa