Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Lingchuan, Guo"'
Autor:
Lin Li, Wencai Li, Chunyan Wu, Yanfeng Xi, Lei Guo, Yuan Ji, Lili Jiang, Ji Li, Jingping Yun, Gang Chen, Yuan Li, Yueping Liu, Dianbin Mu, Yuchen Han, Leina Sun, Qingxin Xia, Xiaodong Teng, Nanying Che, Wei Wu, Xueshan Qiu, Chao Liu, Xiaochu Yan, Daiqiang Li, Zhihong Zhang, Zhe Wang, Yujun Li, Zheng Wang, Lingchuan Guo, Xiu Nie, Jingshu Geng, Jianhua Zhou, Jianming Ying
Publikováno v:
Cancer Communications, Vol 44, Iss 9, Pp 992-1004 (2024)
Abstract Background Anaplastic lymphoma kinase (ALK) test in advanced non‐small cell lung cancer (NSCLC) can help physicians provide target therapies for patients harboring ALK gene rearrangement. This study aimed to investigate the real‐world te
Externí odkaz:
https://doaj.org/article/202ab237e00e47c6a976722ca36d4c24
Autor:
Yongfeng Bi, Dong Wan, Si Chen, Huafei Chen, Lingchuan Guo, Xiaoshun He, Rong Rong, Jinyuan Xiao, Wei Gao, Sheng Xiao
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Giant cell glioblastoma often exhibits genome instability and is frequently associated with mutations in genes involved in DNA repair pathways including TP53 and DNA mismatch repair genes. Several germline mutations have been identified in giant cell
Externí odkaz:
https://doaj.org/article/f19cc88deb344cccb44be3e5a6c75a9b
Publikováno v:
Cancer Nanotechnology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Background The utilization of liposomes in drug delivery has garnered significant attention due to their efficient drug loading capacity and excellent biocompatibility, rendering them a promising platform for tumor therapy. However, the aver
Externí odkaz:
https://doaj.org/article/9b02bb0cb53648a3a1d0df4ef1475cf8
Autor:
Xiaohan Shen, Jiao Dai, Lingchuan Guo, Zhigang Liu, Liu Yang, Dongmei Gu, Yinghong Xie, Zhuo Wang, Ziming Li, Haimiao Xu, Qihui Shi
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-12 (2024)
Abstract Accurate detection of circulating tumor cells (CTCs) in blood and non-blood body fluids enables generation of deterministic cancer diagnosis and represent a less invasive and safer liquid biopsy approach. Although genomic alternations have b
Externí odkaz:
https://doaj.org/article/223ddf4f04f546949d2ffd1f654d27aa
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 6, Pp n/a-n/a (2024)
Abstract Copper, a trace element and vital cofactor, plays a crucial role in the maintenance of biological functions. Recent evidence has established significant correlations between copper levels, cancer development and metastasis. The strong redox
Externí odkaz:
https://doaj.org/article/6fbbe4fc85534029b974d6221d3fa2f0
Autor:
Junmei Li, Yuhong Wang, Wenhao Shen, Ziyu Zhang, Zhiyue Su, Xia Guo, Pei Pei, Lin Hu, Teng Liu, Kai Yang, Lingchuan Guo
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Complete remission of colorectal cancer (CRC) is still unachievable in the majority of patients by common fractionated radiotherapy, leaving risks of tumor metastasis and recurrence. Herein, clinical CRC samples demonstrated a difference in
Externí odkaz:
https://doaj.org/article/e4ed466ac679430892f84048175951c1
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 7, p 272 (2024)
The p53, a pivotal tumor suppressor, regulates various cellular responses, including DNA repair and apoptosis. Normally, p53 levels are low due to murine double minute clone 2 (MDM2) mediated polyubiquitination. However, stress signals disrupt p53-MD
Externí odkaz:
https://doaj.org/article/517dd98177994059b80c287b11e9bbda
Autor:
Haitao Huang, Na Li, Yingkuan Liang, Rutao Li, Xing Tong, Jinyuan Xiao, Hongzhen Tang, Dong Jiang, Kai Xie, Chen Fang, Shaomu Chen, Guangbin Li, Bin Wang, Jiaqian Wang, Haitao Luo, Lingchuan Guo, Haitao Ma, Wei Jiang, Yu Feng
Publikováno v:
Clinical and Translational Medicine, Vol 13, Iss 11, Pp n/a-n/a (2023)
Abstract Background Biopsies obtained from primary oesophageal squamous cell carcinoma (ESCC) guide diagnosis and treatment. However, spatial intra‐tumoral heterogeneity (ITH) influences biopsy‐derived information and patient responsiveness to th
Externí odkaz:
https://doaj.org/article/1453d8813e374a2f9260060233cc5e30
Autor:
Rui Qian, Xuan Yi, Teng Liu, Hua Chen, Yuhong Wang, Lin Hu, Lingchuan Guo, Kai Yang, Haijun Deng
Publikováno v:
Advanced Science, Vol 10, Iss 32, Pp n/a-n/a (2023)
Abstract Intra/extracellular ion content affects the growth and metastasis of tumor cells, as well as the efficacy of various antitumor therapies. Herein, a carbonic anhydrase inhibitor (CAI) is loaded onto pH‐responsive calcium carbonate (CaCO3) n
Externí odkaz:
https://doaj.org/article/16923b7547bc4f3187441ccbe4cf50f5
Autor:
Huanwen Wu, Zicheng Yu, Yueping Liu, Lei Guo, Lianghong Teng, Lingchuan Guo, Li Liang, Jing Wang, Jie Gao, Ruiyu Li, Ling Yang, Xiu Nie, Dan Su, Zhiyong Liang
Publikováno v:
Cancer Communications, Vol 42, Iss 12, Pp 1367-1386 (2022)
Abstract Background Neuroendocrine carcinomas of the gastrointestinal tract (GI‐NECs) remain a disease of grim prognosis with limited therapeutic options. Their molecular characteristics are still undefined. This study aimed to explore the underlyi
Externí odkaz:
https://doaj.org/article/628d309e81be4b83b166a7ab7593aa32