Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lingchen Tan"'
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0307512 (2024)
The multifunctional autoprocessing repeat-in-toxin (MARTX) toxin is the primary virulence factor of Vibrio vulnificus displaying cytotoxic and hemolytic properties. The cysteine protease domain (CPD) is responsible for activating the MARTX toxin by c
Externí odkaz:
https://doaj.org/article/0e89c1ace7d64d3b846c2735602aa723
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The membrane contact sites (MCSs) between the ER and late endosomes (LEs) are essential for the regulation of endosomal protein sorting, dynamics, and motility. PDZD8 is an ER transmembrane protein containing a Synaptotagmin-like Mitochondri
Externí odkaz:
https://doaj.org/article/c356627450f1438195c4b1d42f67f384
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0248781 (2021)
Human ORP3 belongs to the oxysterol-binding protein (OSBP) family of lipid transfer proteins and is involved in lipid trafficking and cell signaling. ORP3 localizes to the ER-PM interfaces and is implicated in lipid transport and focal adhesion dynam
Externí odkaz:
https://doaj.org/article/7f7c3e9be565465facb7c2c5b1edcf18
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0211724 (2019)
Oxysterol-binding protein (OSBP) and OSBP-related proteins (ORPs) constitute a family of lipid transfer proteins conserved in eukaryotes. ORP1 transports cholesterol at the interface between the late endosomes/lysosomes (LELs) and the endoplasmic ret
Externí odkaz:
https://doaj.org/article/7f2111b8cbf249e6a84ad99dea949a43
Publikováno v:
Nature Chemical Biology. 18:1253-1262
Fungal transcription factor Upc2 senses ergosterol levels and regulates sterol biosynthesis and uptake. Constitutive activation of Upc2 causes azole resistance in Candida species. We determined the structure of ergosterol-bound Upc2, revealing the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105413fb5aa2ffad66cf5aa75e279a18
https://doi.org/10.1038/s41589-022-01117-0
https://doi.org/10.1038/s41589-022-01117-0
Publikováno v:
Acta crystallographica. Section D, Structural biology. 78(Pt 7)
Sec14-like phosphatidylinositol transfer proteins (PITPs) are involved in lipid metabolism and phosphatidylinositol 4-phosphate signaling by transporting phosphatidylinositol (PI) and a secondary ligand between the organellar membranes in eukaryotes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e4698833925de6ef27c3054dbaadced
https://pubmed.ncbi.nlm.nih.gov/35775985
https://pubmed.ncbi.nlm.nih.gov/35775985
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
The membrane contact sites (MCSs) between the ER and late endosomes (LEs) are essential for the regulation of endosomal protein sorting, dynamics, and motility. PDZD8 is an ER transmembrane protein containing a Synaptotagmin-like Mitochondrial lipid-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d8e990148aab8834a05ac8b1bd73ee
https://pubmed.ncbi.nlm.nih.gov/34552186
https://pubmed.ncbi.nlm.nih.gov/34552186
Publikováno v:
Biochemical and biophysical research communications. 520(2)
The steroidogenic acute regulatory protein (StAR)-related lipid transfer domain-4 (STARD4) is a sterol-binding protein that is involved in cholesterol homeostasis by intracellular sterol transport. In this work, we determined the crystal structures o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f46ed28af8a6bff64d16858c5e750f
https://pubmed.ncbi.nlm.nih.gov/31607485
https://pubmed.ncbi.nlm.nih.gov/31607485
Publikováno v:
SCIENTIFIC REPORTS(7)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Peroxisome proliferator-activator receptor (PPAR) γ is a nuclear hormone receptor that regulates glucose homeostasis, lipid metabolism, and adipocyte function. PPARγ is a target for thiazolidinedione (TZD) class of drugs which are widely used for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23cdc95f7a0d8ed756795a398b9caf33
http://open-repository.kisti.re.kr/cube/handle/open_repository/485310.do
http://open-repository.kisti.re.kr/cube/handle/open_repository/485310.do
