Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Lingchen Guo"'
Publikováno v:
Neurochemical Research. 36:904-912
Alzheimer's disease (AD) is a neurodegenerative disorder that affects the elderly population. Deposition of beta-amyloid (Aβ) in the brain is a hallmark of AD pathology. In our previous study, we have constructed a cell line expressing human APP695
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190ba2ba2be00f57acd9a14ccdf67b1a
https://doi.org/10.1007/s11064-011-0420-7
https://doi.org/10.1007/s11064-011-0420-7
Publikováno v:
Chemico-Biological Interactions. 181:138-143
Panaxydol, a polyacetylene compound isolated from Panax ginseng, exerts anti-proliferative effects against malignant cells. No previous study, however, has been reported on its effects on hepatocellular carcinoma cells. Here, we investigated the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6587fc44f946e088cb7879658f8eab31
https://doi.org/10.1016/j.cbi.2009.04.015
https://doi.org/10.1016/j.cbi.2009.04.015
Publikováno v:
Molecular Biology Reports. 32:265-271
Ubiquitin and other ubiquitin-like proteins play important roles in post-translational modification. They are phylogenetically well-conserved in eukaryotes. Activated by other proteins, ubiquitin and ubiquitin-like proteins can covalently modify targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886ef8e46ada542086940510426e7da1
https://doi.org/10.1007/s11033-005-4822-y
https://doi.org/10.1007/s11033-005-4822-y
Autor:
Linxia Song, Guang Yang, Zhang Hongmei, Jin Xu, Xinbing Yu, Zhongdao Wu, Xuchu Hu, Jianfeng Dai, Lingchen Guo, Nancai Zheng, Shaohua Gu, Jian Xu, Kang Ying, Chaoneng Ji
Publikováno v:
Parasitology Research. 95:406-412
Adenylate kinase (AK) is a ubiquitous enzyme that contributes to the homeostasis of adenine nucleotides in living cells. AK catalyzes reversible high energy phosphoryl transfer reactions between ATP (or GTP) and AMP to generate ADP (or GDP). From a C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3737c7461a328f7ab2f73bdbe695b3e5
https://doi.org/10.1007/s00436-005-1305-y
https://doi.org/10.1007/s00436-005-1305-y
Autor:
Jianfeng Dai, Lingchen Guo, Xinbing Yu, Guang Yang, Jian Xu, Zhongdao Wu, Chaoneng Ji, Shaohua Gu, Jin Xu, Xuchu Hu, Kang Ying, Chen Shouyi, Nancai Zheng, Linxia Song
Publikováno v:
Parasitology Research. 94:227-232
The ubiquitin-proteasome system is an essential mechanism for protein degradation in eukaryotes. Protein ubiquitination is composed of a series of enzymatic reactions. The ubiquitin-conjugating enzyme (E2) is one of the important enzymes involved in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df533ff024d76e321fc4a9cbf56b7c50
https://doi.org/10.1007/s00436-004-1206-5
https://doi.org/10.1007/s00436-004-1206-5
Autor:
Xiaohua Ni, Chaoneng Ji, Yumin Mao, Lingchen Guo, Haipeng Cheng, Robert Chunhua Zhao, Shaohua Gu, Kang Ying, Gentao Cao
Publikováno v:
Journal of Human Genetics. 48:0101-0106
Protein 4.1 is an important structural protein that is expressed in erythroid and in a variety of nonerythroid tissues. In mammalian erythrocytes, it plays a key role in regulating the physical properties of mechanical stability and deformability in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e60512b4a2b6dfeb2184bdf6ada092e
https://doi.org/10.1007/s100380300015
https://doi.org/10.1007/s100380300015
Autor:
Min Jiang, Yumin Mao, Xie Yi, Yushu Ma, Gentao Cao, Haipeng Cheng, Chaoneng Ji, Lingchen Guo, Xiaohua Ni, Shaohua Gu
Publikováno v:
Journal of Human Genetics. 47:373-376
Cyclic adenosine monophosphate (cAMP) response element-binding (CREB) proteins are a family of mammalian transcription activators. We identified a novel human CREB gene ( CREB4) that was 1592 bp long and encoded a protein of 395 amino acid residues.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06123cf9f96e23801750674b0e87d573
https://doi.org/10.1007/s100380200053
https://doi.org/10.1007/s100380200053
Autor:
Yumin Mao, Xie Yi, Haipeng Cheng, Min Jiang, Yangsheng Jin, Xiaohua Ni, Lingchen Guo, Yushu Ma
Publikováno v:
Journal of Genetics. 81:13-17
We report cloning and some features of a novel human gene, MATH2, which encodes a protein of 337 amino acid residues with a basic helix loop helix domain and exhibits 98% similarity to mouse Math2. Results of Northern blot analysis revealed two trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0242ab4f2060acc77ceb15c6a6d23e13
https://doi.org/10.1007/bf02715865
https://doi.org/10.1007/bf02715865
Autor:
Yontao Lu, Grace Q. Zhao, Lingchen Guo, Zhaohui Johnny Sun, Kang Ying, Ming Li, Shengrong Lin, Paul Tang, Yingyu Wang, Yi Huang, Malek Faham, Dana Yeo, Xin-Xing Li, Zhiqian Hu, Li Weng, WeiWei Xiao, Min Li, Hongyan Wang
Publikováno v:
Journal of Clinical Oncology. 35:e23067-e23067
e23067 Background: Circulating tumor DNA (ctDNA) is a promising biomarker for the detection of minimal residual disease and monitoring treatment in patients with CRC. The performance demands of any technology used for this purpose, however, are treme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4a97efc4b0aa93d2634353206d29791
https://doi.org/10.1200/jco.2017.35.15_suppl.e23067
https://doi.org/10.1200/jco.2017.35.15_suppl.e23067
Autor:
Johnny Sun, Paul Tang, Shengrong Lin, Lingchen Guo, Wei Shen, Hongyan Wang, Kang Ying, Xiaozheng Kang, Yi Huang, Li Weng, Grace Q. Zhao
Publikováno v:
Cancer Research. 76:1375-1375
In order to take advantage of the narrow time window for optimal treatment efficacy, highly sensitive disease monitoring is critical in the successful management of cancer. Currently, treatment efficacy is assessed by using a combination of protein c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63e7e0b30389a2d651bbd9ec7f8925da
https://doi.org/10.1158/1538-7445.am2016-1375
https://doi.org/10.1158/1538-7445.am2016-1375