Výsledky vyhledávání - "LingTian Min"

Akademický článek

Quercitrin alleviates cartilage extracellular matrix degradation and delays ACLT rat osteoarthritis development: An in vivo and in vitro study

Autor: Hanli Guo, Weifeng Yin, Ziling Zou, Chao Zhang, Minghui Sun, Lingtian Min, Lei Yang, Lingyi Kong

Publikováno v: Journal of Advanced Research, Vol 28, Iss , Pp 255-267 (2021)

Introduction: Disruptions of extracellular matrix (ECM) degradation homeostasis play a significant role in the pathogenesis of osteoarthritis (OA). Matrix metalloproteinase 13 (MMP13) and collagen Ⅱ are important components of ECM. Earlier we found

Externí odkaz: https://doaj.org/article/4ff8cc37ad9441569b04c669f05369a0

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Akademický článek

Secreted frizzled-related protein 5 (SFRP5) protects ATDC5 cells against LPS-induced inflammation and apoptosis via inhibiting Wnt5a/JNK pathway

Autor: Minghui Sun, Weijun Wang, Lingtian Min, Cheng Chen, Qing Li, Wenjie Weng

Publikováno v: Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-8 (2021)

Abstract Background Secreted frizzled-related protein 5 (SFRP5) is an endogenous inhibitor of Wnt5a (wingless-type family member 5a), which has been implicated in anti-inflammatory response. In this study, we aimed to investigate whether SFRP5 could

Externí odkaz: https://doaj.org/article/433a23f637b84cd8ba6a115593a5e587

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Abnormal femur rotation in patients with recurrent patellar dislocation: A study on upright standing three-dimensionally reconstructed EOS images

Autor: Wenjie Weng, Cheng Chen, Weijun Wang, Minghui Sun, Lingtian Min

Publikováno v: The Knee. 32:131-139

The measurements of lower extremity rotational deformities in patients with recurrent patellar dislocation (RPD) in the standing position are available with the application of the EOS imaging system. The aim of our case-control study was to identify

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::677de24409216ad7b8d2d0b6aeb19f0c
https://doi.org/10.1016/j.knee.2021.08.011

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Secreted frizzled-related protein 5 (SFRP5) protects ATDC5 cells against LPS-induced inflammation and apoptosis via inhibiting Wnt5a/JNK pathway

Autor: Wei-jun Wang, Cheng Chen, Qing Li, Minghui Sun, Wenjie Weng, Lingtian Min

Publikováno v: Journal of Orthopaedic Surgery and Research, Vol 16, Iss 1, Pp 1-8 (2021)
Journal of Orthopaedic Surgery and Research

Background Secreted frizzled-related protein 5 (SFRP5) is an endogenous inhibitor of Wnt5a (wingless-type family member 5a), which has been implicated in anti-inflammatory response. In this study, we aimed to investigate whether SFRP5 could protect c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988f4a45c808e8dedd23dde922aac20c
https://doaj.org/article/433a23f637b84cd8ba6a115593a5e587

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Quercitrin alleviates cartilage extracellular matrix degradation and delays ACLT rat osteoarthritis development: An in vivo and in vitro study

Autor: Lingtian Min, Chao Zhang, Lei Yang, Hanli Guo, Ziling Zou, Wei-feng Yin, Ming-hui Sun, Ling-Yi Kong

Publikováno v: Journal of Advanced Research
Journal of Advanced Research, Vol 28, Iss, Pp 255-267 (2021)

Graphical abstract
Highlights • The p110α protein levels were reduced in articular cartilage of ACLT rats. • Quercitrin prominently alleviated tibial subchondral bone loss in ACLT rats. • The p110α mRNA levels were dramatically downregul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e848599fd8ab8a0d79a4b172bba66431
https://doi.org/10.1016/j.jare.2020.06.020

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Combination of molecular docking and liver transcription sequencing analysis for the evaluation of salt-processed psoraleae fructus-induced hepatotoxicity in ovariectomized mice

Autor: Yu Wu, LingTian Min, Yan Xu, Heng Liu, Nong Zhou, ZhengYing Hua, ChunMei Mei, Ziyu Jiang, Weidong Li

Publikováno v: Journal of ethnopharmacology. 288

Salt-processed Psoraleae fructus (SPF) is widely used as a phytoestrogen-like agent in the treatment of osteoporosis. However, SPF-associated hepatotoxicity is a known health hazard. Cholestasis is often associated with SPF-induced hepatotoxicity. No

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b0756e44549fadcb52e8cd873550a3f
https://pubmed.ncbi.nlm.nih.gov/35032590

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Comparative in vivo pharmacokinetics study of affeic acid, isoferulic acid and ferulic acid in crude and three different prepared Cimicifuga foetida L

Autor: Yongjun Cao, Lingtian Min, Yu Wu, Daguo Mi, Aihua Yang, Yan Xu, Zhengying Hua, Shuijie Shen, Weidong Li

Publikováno v: Biomedical chromatography : BMCREFERENCES. 34(9)

Our study investigated the differences in pharmacokinetics of three major components of crude Cimicifuga foetida L. and its fried product and honey- and liquor-prepared products. A rapid and sensitive ultra-high performance liquid chromatography with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb43d2fccf124ef343ec642c95faac2
https://pubmed.ncbi.nlm.nih.gov/32335934

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A network pharmacology strategy to investigate the anti-osteoarthritis mechanism of main lignans components of Schisandrae Fructus

Autor: Lingtian Min, Daguo Mi, Yu Wu, Cheng Chen, Gang Cao

Publikováno v: International Immunopharmacology. 98:107873

Osteoarthritis (OA) is a chronic age-related progressive joint disorder. Degradation of the cartilage extracellular matrix (ECM) is considered a hallmark of OA and may be a target for new therapeutic methods. Schisandrae Fructus (SF) has been shown t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6db49eeeac04088f7bd88870d1c6efe
https://doi.org/10.1016/j.intimp.2021.107873

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