Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Ling-yun Xu"'
Metformin exhibits antiproliferation activity in breast cancer via miR-483-3p/METTL3/m6A/p21 pathway
Autor:
Lin Cheng, Xu Zhang, Yu-Zhou Huang, Yu-Lan Zhu, Ling-Yun Xu, Zhi Li, Xin-Yuan Dai, Liang Shi, Xu-Jie Zhou, Ji-Fu Wei, Qiang Ding
Publikováno v:
Oncogenesis, Vol 10, Iss 1, Pp 1-14 (2021)
Abstract Evidence suggests that metformin might be a potential candidate for breast cancer treatment. Yet, its relevant molecular mechanisms remain to be fully investigated. We found that metformin could suppress the N6-methyladenosine (m6A) level in
Externí odkaz:
https://doaj.org/article/3eb1fce86b644300aac61cd01ec9eb79
Publikováno v:
Pediatrics and Neonatology, Vol 57, Iss 5, Pp 396-401 (2016)
To analyze the correlation of cytokines with clinical inflammatory indexes in systemic onset juvenile idiopathic arthritis (SOJIA). Methods: A total of 30 active SOJIAs, 30 remission SOJIAs, and 20 normal controls were enrolled. The clinical inflamma
Externí odkaz:
https://doaj.org/article/96e50e76df7f40728d1f6f935a2e33d6
Publikováno v:
Alternative Therapies in Health & Medicine. Apr2023, Vol. 29 Issue 3, p127-133. 7p.
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Cancer Management and Research. 11:5425-5435
Background: Resistance to docetaxel is a major obstacle to effective treatment of breast cancer. Exosomal microRNAs (miRNAs) have recently been introduced in cell-to-cell transmission of chemoresistance between heterogeneous populations of tumor cell
Publikováno v:
Biomedical Journal of Scientific & Technical Research. 25
Natural products provide a resource of numerous active compounds for drug discovery. Identification and investigation...
Publikováno v:
Biomedical Journal of Scientific & Technical Research. 25
Article Focus: This study evaluates the expression of ER, PgR, Her2/neu and correlates their expression with cinico-pathological parameters...
Publikováno v:
International Journal of Antennas and Propagation, Vol 2012 (2012)
We introduce an iterative least squares method (ILS) for estimating the 2D-DOA and frequency based on L-shaped array. The ILS iteratively finds direction matrix and delay matrix, then 2D-DOA and frequency can be obtained by the least squares method.
Externí odkaz:
https://doaj.org/article/1d8b6782856d46d99187ea34f896a6e1
Publikováno v:
Oncology Letters.
GTPase activating proteins (RhoGAPs) serve significant roles in multiple aspects of tumor biology. Genes encoding RhoGAPs (ARHGAP), which switch off Rho-like GTPases, are responsible for breast cancer biogenesis. However, the identification of suitab
Publikováno v:
Bioscience Reports. 39
Background: Ribonucleotide reductase M2 subunit (RRM2) plays vital roles in many cellular processes such as cell proliferation, invasiveness, migration, angiogenesis, senescence, and tumorigenesis. However, the prognostic significance of RRM2 gene in