Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ling-yun Chu"'
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152166 (2016)
The endothelial junction is tightly controlled to restrict the passage of blood cells and solutes. Disruption of endothelial barrier function by bacterial endotoxins, cytokines or growth factors results in inflammation and vascular damage leading to
Externí odkaz:
https://doaj.org/article/449283d47d514b00a23a420270b779da
Autor:
Huei-Hsuan Cheng, Kai-Hsuan Wang, Ling-yun Chu, Tzu-Ching Chang, Cheng-Chin Kuo, Kenneth K Wu
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88507 (2014)
Quiescent fibroblasts possess unique genetic program and exhibit high metabolic activity distinct from proliferative fibroblasts. In response to inflammatory stimulation, quiescent fibroblasts are more active in expressing cyclooxygenase-2 and other
Externí odkaz:
https://doaj.org/article/22876c62dd85435a924c927fa6e7799b
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69702 (2013)
We hypothesized that prostacyclin (PGI2) protects vascular smooth muscle cell (VSMC) against apoptosis and phenotypic switch through peroxisome proliferator-activated receptor-α (PPARα) activation and 14-3-3 upregulation. Here we showed that transf
Externí odkaz:
https://doaj.org/article/ce43496addb74a138c9aabf73b5fd7cd
Autor:
LING-YUN CHU, 儲凌雲
93
In this study, functional KSR (Kinase Suppressor of Ras) complex was isolated from zebrafish embryos at cleavage stage. During the process of KSR purification, we found that there may be an interaction between RACK1 (Receptor for Activated C
In this study, functional KSR (Kinase Suppressor of Ras) complex was isolated from zebrafish embryos at cleavage stage. During the process of KSR purification, we found that there may be an interaction between RACK1 (Receptor for Activated C
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/16999481499934188047
Publikováno v:
Oncotarget
We reported previously that human fibroblasts release 5-methoxytryptophan (5-MTP) which inhibits cancer cell COX-2 overexpression and suppresses cancer cell migration and metastasis. To determine whether fibroblasts block cancer cell epithelial mesen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81135672988d0e84ad3edcff19426cc9
https://doi.org/10.18632/oncotarget.9111
https://doi.org/10.18632/oncotarget.9111
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Rapamycin is a widely used autophagy inducer and has been shown to suppress development of atherosclerosis in animal models. However, the side effect is severe including hyperlipidemia. We identified isoleukotoxin, a metabolite of linoleic acid, as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1982db08f60b0449150b174fa49e3fad
https://doi.org/10.1161/atvb.38.suppl_1.654
https://doi.org/10.1161/atvb.38.suppl_1.654
Autor:
Ling-Yun Chu, Roy L. Silverstein
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32:760-767
Objective— CD36 phosphorylation on its extracellular domain inhibits binding of thrombospondin-1. The mechanisms of cellular CD36 ectodomain phosphorylation and whether it can be regulated in cells are not known. We determined structure-function re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16f016e836dfbed6df89c26d1e609631
https://doi.org/10.1161/atvbaha.111.242511
https://doi.org/10.1161/atvbaha.111.242511
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0152166 (2016)
PLoS ONE, Vol 11, Iss 3, p e0152166 (2016)
The endothelial junction is tightly controlled to restrict the passage of blood cells and solutes. Disruption of endothelial barrier function by bacterial endotoxins, cytokines or growth factors results in inflammation and vascular damage leading to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::183b18cafbf5f2260802f3400f08c36a
https://pubmed.ncbi.nlm.nih.gov/27002329
https://pubmed.ncbi.nlm.nih.gov/27002329
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
VE-cadherin at adherens junction is important in maintaining the integrity of endothelium. Inflammatory cytokines and growth factors such as TNFα and VEGF have been reported to suppress endothelial VE-cadherin level and increase endothelial permeabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::029d82887299a89e05828e1ec004b998
https://doi.org/10.1161/atvb.35.suppl_1.206
https://doi.org/10.1161/atvb.35.suppl_1.206
Publikováno v:
Prostaglandinsother lipid mediators.
Vascular integrity is protected by the lining endothelial cells (ECs) through structural and molecular protective mechanisms. In response to external stresses, ECs are dynamic in producing protective molecules such as prostacyclin (PGI2). PGI2 is kno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40ec960e670fec04d619142c72feb5a
https://pubmed.ncbi.nlm.nih.gov/25910681
https://pubmed.ncbi.nlm.nih.gov/25910681