Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Ling-xiao Deng"'
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
The landscape of therapeutic deep brain stimulation (DBS) for locomotor function recovery is rapidly evolving. This review provides an overview of electrical neuromodulation effects on spinal cord injury (SCI), focusing on DBS for motor functional re
Externí odkaz:
https://doaj.org/article/c8aad77c5558468eb5fe85ddb1eeba29
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 5, Pp 933-939 (2023)
Chx10-expressing V2a (Chx10+V2a) spinal interneurons play a large role in the excitatory drive of motoneurons. Chemogenetic ablation studies have demonstrated the essential nature of Chx10+V2a interneurons in the regulation of locomotor initiation, m
Externí odkaz:
https://doaj.org/article/47af90c768fd4a61ae7b98693c5fc42b
Autor:
Nai-Kui Liu, Ling-Xiao Deng, Miao Wang, Qing-Bo Lu, Chunyan Wang, Xiangbing Wu, Wei Wu, Ying Wang, Wenrui Qu, Qi Han, Yongzhi Xia, Baylen Ravenscraft, Jin-Lian Li, Si-Wei You, Peter Wipf, Xianlin Han, Xiao-Ming Xu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-16 (2022)
Abstract Alterations in phospholipids have long been associated with spinal cord injury (SCI). However, their specific roles and signaling cascades in mediating cell death and tissue repair remain unclear. Here we investigated whether alterations of
Externí odkaz:
https://doaj.org/article/25441a47b06f41fe8fc1e177c855cf32
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 1, Pp 186-191 (2021)
Biomaterial bridging provides physical substrates to guide axonal growth across the lesion. To achieve efficient directional guidance, combinatory strategies using permissive matrix, cells and trophic factors are necessary. In the present study, we e
Externí odkaz:
https://doaj.org/article/9a78e670c4404ef48095ebfed57f7e5d
Autor:
Wen-Rui Qu, Zhe Zhu, Jun Liu, De-Biao Song, Heng Tian, Bing-Peng Chen, Rui Li, Ling-Xiao Deng
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 1, Pp 93-98 (2021)
Peripheral nerve injury (PNI) is common and, unlike damage to the central nervous system injured nerves can effectively regenerate depending on the location and severity of injury. Peripheral myelinating glia, Schwann cells (SCs), interact with vario
Externí odkaz:
https://doaj.org/article/28f333bdad114c719d13e87e7af7945e
Autor:
Ying Wang, Wei Wu, Xiangbing Wu, Yan Sun, Yi P Zhang, Ling-Xiao Deng, Melissa Jane Walker, Wenrui Qu, Chen Chen, Nai-Kui Liu, Qi Han, Heqiao Dai, Lisa BE Shields, Christopher B Shields, Dale R Sengelaub, Kathryn J Jones, George M Smith, Xiao-Ming Xu
Publikováno v:
eLife, Vol 7 (2018)
Retrogradely-transported neurotrophin signaling plays an important role in regulating neural circuit specificity. Here we investigated whether targeted delivery of neurotrophin-3 (NT-3) to lumbar motoneurons (MNs) caudal to a thoracic (T10) contusive
Externí odkaz:
https://doaj.org/article/8a30e0b29f914c39a805040cd8856858
Autor:
Wen-Yuan Li, Ying Wang, Feng-Guo Zhai, Ping Sun, Yong-Xia Cheng, Ling-Xiao Deng, Zhen-Yu Wang
Publikováno v:
Neural Plasticity, Vol 2017 (2017)
DPSN axons mediate and maintain a variety of normal spinal functions. Unsurprisingly, DPSN tracts have been shown to mediate functional recovery following SCI. KLF7 could contribute to CST axon plasticity after spinal cord injury. In the present stud
Externí odkaz:
https://doaj.org/article/325f2b3a7c0b470d80012455fa168c0d
Autor:
Jian-Guo Hu, Xiao-Fei Wang, Ling-Xiao Deng, Nai-Kui Liu, Xiang Gao, Jinhui Chen, Feng C. Zhou, Xiao-Ming Xu Ph.D
Publikováno v:
Cell Transplantation, Vol 22 (2013)
Oligodendrocyte (OL) replacement can be a promising strategy for spinal cord injury (SCI) repair. However, the poor posttransplantation survival and inhibitory properties to axonal regeneration are two major challenges that limit their use as donor c
Externí odkaz:
https://doaj.org/article/f67e42eaf565420aba3061208ed13436
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 1, Pp 93-98 (2021)
Neural Regeneration Research
Neural Regeneration Research
Peripheral nerve injury (PNI) is common and, unlike damage to the central nervous system injured nerves can effectively regenerate depending on the location and severity of injury. Peripheral myelinating glia, Schwann cells (SCs), interact with vario
Autor:
Xiaolong Du, Xiaojing Lin, Chen Chen, Ling-Xiao Deng, Tingbao Zhao, Shaonan Wen, Xiao Ming Xu, Melissa Walker, Heqiao Dai
Publikováno v:
Journal of Visualized Experiments.
Incomplete spinal cord injury (SCI) often leads to impairments of sensorimotor functions and is clinically the most frequent type of SCI. Human Brown-Sequard syndrome is a common type of incomplete SCI caused by a lesion to one half of the spinal cor