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pro vyhledávání: '"Ling-Yi Kao"'
Autor:
Ling-Yi Kao, Wei-Ting Chao
Publikováno v:
Chinese Journal of Physiology, Vol 64, Iss 1, Pp 43-50 (2021)
Focal adhesion (FA) turnover has been demonstrated to play an important role in cell migration; however, the mechanism of FA turnover is complicated and requires further investigation. In this study, Rab11, which is involved in endosome recycling, wa
Externí odkaz:
https://doaj.org/article/9226fe4d4b13476aa2c7d3a3cac86ab8
Autor:
Wei-Ting Chao, Wan-Chen Wei, Ling-Yi Kao, Shih-Hsien Chuang, Hsiang-Ling Chiu, Yi-Che Wu, Yuan-Chiang Chung, Sun Wei-Ting
Publikováno v:
Cancer Research. 78:3729-3729
Epidermal growth factor receptor (EGFR) is the key receptor for cancer cell growing, cetuximab is the monoclonal antibody that targets EGFR and was approved for treatment of colorectal, head and neck cancer. However, patients with KRAS /BRAF mutation
Publikováno v:
Cancer Research. 78:4035-4035
Colorectal carcinoma is the most common cancer worldwide. Cetuximab is the first-line target drug for late-stage metastatic colon cancer treatment; however, resistance to it was found in 45% patients having KRAS mutation. Therefore, the alternative s
Publikováno v:
Cancer Research. 78:5163-5163
Focal adhesion (FA) turnover has been demonstrated to play an important role in controlling cell migration and cancer metastasis. FA disassembly was shown to be regulated by endocytosis during cell migration. Rabs are a kind of GTPase that participat
Publikováno v:
Cancer Research. 78:4042-4042
Trastuzumab emtansine (T-DM1, Kadcyla) is an antibody-drug conjugate (ADC) that was recently approved by the Federal Drug Administration (FDA) of the USA for the treatment of HER-2-positive metastatic breast cancer. The drug sensitivity of ADCs depen
Publikováno v:
Cancer Research. 74:LB-69
Cell migration is central for many physiological and pathological processes, including embryogenesis, tissue repair, inflammatory responses, and cancer metastasis. Focal adhesion (FA) turnover has been demonstrated to play important role in controlli