Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ling-Yan Su"'
Autor:
Qiang Chen, Luis Aguirre, Guoming Liang, Huanhuan Zhao, Tao Dong, Felix Borrego, Itziar de Rojas, Qichan Hu, Christopher Reyes, Ling-Yan Su, Bao Zhang, James D. Lechleiter, Harald H. H. Göring, Philip L. De Jager, Joel E. Kleinman, Thomas M. Hyde, Pan P. Li, Agustín Ruiz, Daniel R. Weinberger, Sudha Seshadri, Liang Ma
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-18 (2024)
Abstract Background The APOE gene is the strongest genetic risk factor for late-onset Alzheimer’s Disease (LOAD). However, the gene regulatory mechanisms at this locus remain incompletely characterized. Methods To identify novel AD-linked functiona
Externí odkaz:
https://doaj.org/article/5374844758ed40dc95d178d7f3ae89ee
Autor:
Ling-Yan Su, Lijin Jiao, Qianjin Liu, Xinhua Qiao, Ting Xie, Zhiyu Ma, Min Xu, Mao-Sen Ye, Lu-Xiu Yang, Chang Chen, Yong-Gang Yao
Publikováno v:
Redox Biology, Vol 75, Iss , Pp 103239- (2024)
Morphine, a typical opiate, is widely used for controlling pain but can lead to various side effects with long-term use, including addiction, analgesic tolerance, and hyperalgesia. At present, however, the mechanisms underlying the development of mor
Externí odkaz:
https://doaj.org/article/c8cc0f41459044a7a0b0957ba6e4296d
Autor:
Qianjin Liu, Tianle Gu, Ling-Yan Su, Lijin Jiao, Xinhua Qiao, Min Xu, Ting Xie, Lu-Xiu Yang, Dandan Yu, Ling Xu, Chang Chen, Yong-Gang Yao
Publikováno v:
Redox Biology, Vol 47, Iss , Pp 102172- (2021)
Innate immunity is the first line of host defense against pathogens. This process is modulated by multiple antiviral protein modifications, such as phosphorylation and ubiquitination. Here, we showed that cellular S-nitrosoglutathione reductase (GSNO
Externí odkaz:
https://doaj.org/article/48096fc880994438ade724f596817197
Autor:
Qianjin Liu, Ling-Yan Su, Chunli Sun, Lijin Jiao, Ying Miao, Min Xu, Rongcan Luo, Xin Zuo, Rongbin Zhou, Ping Zheng, Wei Xiong, Tian Xue, Yong-Gang Yao
Publikováno v:
Redox Biology, Vol 34, Iss , Pp 101560- (2020)
Morphine is frequently used for pain relief, but long-term morphine therapy in patients with chronic pain results in analgesic tolerance and hyperalgesia. There are no effective therapeutic treatments that limit these detrimental side effects. We fou
Externí odkaz:
https://doaj.org/article/a10dbc9c9cbd44ef8d03191d254b4004
Autor:
Dong Wang, Ling-Yan Su, A-Mei Zhang, Yu-Ye Li, Xiao-An Li, Ling-Ling Chen, Heng Long, Yong-Gang Yao
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e38848 (2012)
BackgroundLeprosy is a chronic infectious disease caused by Mycobacterium leprae, an unculturable pathogen with an exceptionally eroded genome. The high level of inactivation of gene function in M. leprae, including many genes in its metabolic pathwa
Externí odkaz:
https://doaj.org/article/4c776fc6eefd4c43af0df312445b1c86
Autor:
Lijin Jiao, Ling-Yan Su, Qianjin Liu, Rongcan Luo, Xinhua Qiao, Ting Xie, Lu-Xiu Yang, Chang Chen, Yong-Gang Yao
Publikováno v:
Free Radical Biology and Medicine. 189:111-121
The S-nitrosoglutathione reductase (GSNOR) is a key denitrosating enzyme that regulates protein S-nitrosation, a process which has been found to be involved in the pathogenesis of Parkinson's disease (PD). However, the physiological function of GSNOR
Publikováno v:
Molecular Neurobiology. 58:4628-4638
Drug addiction is a global health problem and continues to place an enormous financial burden on society. This addiction is characterized by drug dependence sensitization and craving. Morphine has been widely used for pain relief, but chronic adminis
Autor:
Lu-Xiu Yang, Ting Xie, Ling-Yan Su, Min Xu, Chang Chen, Tianle Gu, Qianjin Liu, Lijin Jiao, Xinhua Qiao, Ling Xu, Yong-Gang Yao, Dandan Yu
Publikováno v:
Redox Biology
Redox Biology, Vol 47, Iss, Pp 102172-(2021)
Redox Biology, Vol 47, Iss, Pp 102172-(2021)
Innate immunity is the first line of host defense against pathogens. This process is modulated by multiple antiviral protein modifications, such as phosphorylation and ubiquitination. Here, we showed that cellular S-nitrosoglutathione reductase (GSNO
Autor:
Ling-Yan Su, Yuan Li, Qianjin Liu, Lijin Jiao, Jing Shen, Lu-Xiu Yang, Ti-Fei Yuan, Yong-Gang Yao
Publikováno v:
Science China. Life sciences. 65(3)
Autor:
Jing Yang, Rongcan Luo, Li Guiyu, Hejiang Zhou, Deng-Feng Zhang, Min Xu, Ling-Yan Su, Yu Fan, Yong-Gang Yao, Qianjin Liu, Lu-Xiu Yang, Jiali Li
Publikováno v:
Autophagy. 16:52-69
Alzheimer disease (AD) is the most common neurodegenerative disease. An imbalance between the production and clearance of Aβ (amyloid beta) is considered to be actively involved in AD pathogenesis. Macroautophagy/autophagy is a major cellular pathwa