Výsledky vyhledávání - "Ling-Ming Xin"

Glycopeptide ligation via direct aminolysis of selenoester

Autor: Wen-Bo Xu, Chang-Wei Wang, Jing-Jing Du, Ze Lei, Lian Zhang, Jun Guo, Xiao-Fei Gao, Shi-Yao Zou, Ling-Ming Xin

Publikováno v: Chinese Chemical Letters. 29:1127-1130

Direct aminolysis of selenoester in aqueous media was investigated as a glycopeptide ligation strategy. This strategy allows the peptide and glycopeptide ligation to proceed smoothly (even with hindered amino acids) without the need of cysteine resid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d7c0541f43ae63682851d68189871bed
https://doi.org/10.1016/j.cclet.2018.04.016

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Polyfluorophenyl Ester-Terminated Homobifunctional Cross-Linkers for Protein Conjugation

Autor: Jing-Jing Du, Zheng Liu, Jian Wang, Ya-Cong Wang, Xiang-Zhao Chen, Ru-Yan Zhang, Xiao-Fei Gao, Ze Lei, Xu-Guang Yin, Jun Guo, Ling-Ming Xin

Publikováno v: Synlett. 28:1934-1938

Along with N-hydroxysuccinimidyl, p-nitrophenyl, and phenylseleno esters, tetra- and penta-fluorophenyl esters were comparatively evaluated in term of their reactivity and hydrolytic stability. Their homobifunctional cross-linkers were prepared to co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::91e2dc0a64ccb3a3d04fd9305174fb2b
https://doi.org/10.1055/s-0036-1590974

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Preparation of Protein Conjugates via Homobifunctional Diselenoester Cross-Linker

Autor: Xiang-Zhao Chen, Jian Wang, Ling-Ming Xin, Ze Lei, Xu-Guang Yin, Jing-Jing Du, Jun Guo, Xiao-Fei Gao, Xiao-Kang Zhang, Zheng Liu

Publikováno v: Organic Letters. 18:5796-5799

Adipic acid diselenoester was developed as an efficient cross-linker for covalent protein conjugation with a variety of small molecular haptens, including mono- and disaccharides, peptide, fluorescence dye, and nicotine. Compared to the counterparts

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443650334b725f7aaf315bfb148951e6
https://doi.org/10.1021/acs.orglett.6b02568

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Convergent Synthesis of N-Linked Glycopeptides via Aminolysis of ω-Asp p-Nitrophenyl Thioesters in Solution

Autor: Ling-Ming Xin, Jun Guo, Jing-Jing Du, Xiao-Fei Gao, Ze Lei, Zheng Liu

Publikováno v: Organic letters. 18(19)

An efficient N-linked glycosylation reaction between glycosylamines and p-nitrophenyl thioester peptides has been developed. The reaction conditions are mild and compatible with the C-terminal free carboxylic acid group and the unprotected N-linked s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4487f66c0cf79af637ff1ec7c1731a92
https://pubmed.ncbi.nlm.nih.gov/27619788

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