Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ling-Li Gao"'
Discovery of Potent and Novel Dual PARP/BRD4 Inhibitors for Efficient Treatment of Pancreatic Cancer
Autor:
Lei Huang, Qian-Wen Lin, Shuping Wang, Qihua Zhu, Qin Sun, Yungen Xu, Shi-Qi Wu, Shi-Hui Huang, Ling-Li Gao, Liu-Qiong Meng, Yi Zou, Yu Li
Publikováno v:
Journal of Medicinal Chemistry. 64:17413-17435
Targeting poly(ADP-ribose) polymerase1/2 (PARP1/2) is a promising strategy for the treatment of pancreatic cancer with breast cancer susceptibility gene (BRCA) mutation. Inducing the deficiency of homologous recombination (HR) repair is an effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d22c5fe6579643fc94e1bcf16d3612
https://doi.org/10.1021/acs.jmedchem.1c01535
https://doi.org/10.1021/acs.jmedchem.1c01535
Autor:
Shi-Hui Huang, Ran Cao, Qian-Wen Lin, Shi-Qi Wu, Ling-Li Gao, Qin Sun, Qi-Hua Zhu, Yi Zou, Yun-Gen Xu, Shu-Ping Wang
Publikováno v:
European Journal of Medicinal Chemistry. 230:114116
Inducing the deficiency of homologous recombination (HR) repair is an effective strategy to broaden the indication of PARP inhibitors in pancreatic cancer treatment. Repression of BRD4 has been reported to significantly elevate HR deficiency and sens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81cfb7188da7f5bd1792c208e705d7b9
https://doi.org/10.1016/j.ejmech.2022.114116
https://doi.org/10.1016/j.ejmech.2022.114116
Publikováno v:
Chinese Journal of Convalescent Medicine / Zhongguo Liaoyang Yixue; mar2024, Vol. 33 Issue 3, p12-15, 4p
Publikováno v:
Acta Geoscientica Sinica; Sep2023, Vol. 44 Issue 5, p849-866, 18p
One of the important principles of Conservation Agriculture is the permanent soil cover with crop residues which enhances soil and water productivity that leads to improved agricultural productivity. The effect of crop residues on soil moisture conte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948a6e542ed3811f9a1112b048b36e45
One of the important principles of Conservation Agricultural Research is the permanent soil cover with crop residues which enhances soil and water productivity that leads to improved agricultural productivity. The effect of crop residues on soil mois
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a74512ee2f65a7321299ed8b2f694ed
Keeping up to date with advances in material science and applied engineering is essential for those working in the field if they are to understand and tackle the challenges they face in an efficient manner and adopt the best and most appropriate solu
Autor:
Litwack, Gerald
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of i