Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Ling-Gang Wu"'
Autor:
Lisi Wei, Xiaoli Guo, Ehud Haimov, Kazuki Obashi, Sung Hoon Lee, Wonchul Shin, Min Sun, Chung Yu Chan, Jiansong Sheng, Zhen Zhang, Ammar Mohseni, Sudhriti Ghosh Dastidar, Xin-Sheng Wu, Xin Wang, Sue Han, Gianvito Arpino, Bo Shi, Maryam Molakarimi, Jessica Matthias, Christian A. Wurm, Lin Gan, Justin W. Taraska, Michael M. Kozlov, Ling-Gang Wu
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-24 (2024)
Abstract Membrane budding, which underlies fundamental processes like endocytosis, intracellular trafficking, and viral infection, is thought to involve membrane coat-forming proteins, including the most observed clathrin, to form Ω-shape profiles a
Externí odkaz:
https://doaj.org/article/518300501f89466182891e0cc4c55801
Autor:
Ling-Gang Wu, Chung Yu Chan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Membrane fusion and budding mediate fundamental processes like intracellular trafficking, exocytosis, and endocytosis. Fusion is thought to open a nanometer-range pore that may subsequently close or dilate irreversibly, whereas budding trans
Externí odkaz:
https://doaj.org/article/df529918c30c422eaf56a49600515663
Autor:
Wonchul Shin, Ben Zucker, Nidhi Kundu, Sung Hoon Lee, Bo Shi, Chung Yu Chan, Xiaoli Guo, Jonathan T. Harrison, Jaymie Moore Turechek, Jenny E. Hinshaw, Michael M. Kozlov, Ling-Gang Wu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Shin et al. report the molecular mechanics of membrane budding: actin and dynamin pull membrane inward to form a Λ-shape profile; dynamin helices convert Λ- to Ω-shape by constricting Λ’s base, and then constrict Ω-profile’s pore to form a v
Externí odkaz:
https://doaj.org/article/52e7b54f554c4c94b750537319d58671
Light and electron microscopic imaging of synaptic vesicle endocytosis at mouse hippocampal cultures
Publikováno v:
STAR Protocols, Vol 3, Iss 3, Pp 101495- (2022)
Summary: Following the release of neurotransmitters at synaptic vesicles via exocytosis, endocytosis is initiated to retrieve vesicles that have fused with the plasma membrane of nerve terminals and recycle them, thus sustaining synaptic transmission
Externí odkaz:
https://doaj.org/article/41a74671bff2442c8c8993222e639eca
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101404- (2022)
Summary: Real-time confocal and super-resolution imaging reveals membrane dynamics of exo- and endocytosis, including hemi-fusion, fusion pore opening, expansion, constriction, closure (kiss-and-run), fused-vesicle shrinking (shrink fusion), and flat
Externí odkaz:
https://doaj.org/article/0947953066cc480ca8d6595dc1e483b7
Autor:
Ling-Gang Wu, Chung Yu Chan
Publikováno v:
Frontiers in Synaptic Neuroscience, Vol 14 (2022)
Cytoskeletal filamentous actin (F-actin) has long been considered a molecule that may regulate exo- and endocytosis. However, its exact roles remained elusive. Recent studies shed new light on many crucial roles of F-actin in regulating exo- and endo
Externí odkaz:
https://doaj.org/article/2d555fbdfd5e4755a02caf731408f9be
Autor:
Gianvito Arpino, Agila Somasundaram, Wonchul Shin, Lihao Ge, Seth Villareal, Chung Yu Chan, Uri Ashery, Oleg Shupliakov, Justin W. Taraska, Ling-Gang Wu
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103809- (2022)
Summary: Clathrin-mediated endocytosis, the most prominent endocytic mode, is thought to be generated primarily from relatively flat patches of the plasma membrane. By employing conventional and platinum replica electron microscopy and super-resoluti
Externí odkaz:
https://doaj.org/article/b97afdad4fb9476ba4767ca24af811ab
Autor:
Chong-kui Sun, Di Zhou, Zhen Zhang, Liming He, Fan Zhang, Xiaowei Wang, Jie Yuan, Qianming Chen, Ling-Gang Wu, Qin Yang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/b5f3fca03ea0422dbf904d0406f103d5
Autor:
Wonchul Shin, Gianvito Arpino, Sathish Thiyagarajan, Rui Su, Lihao Ge, Zachary McDargh, Xiaoli Guo, Lisi Wei, Oleg Shupliakov, Albert Jin, Ben O’Shaughnessy, Ling-Gang Wu
Publikováno v:
Cell Reports, Vol 30, Iss 2, Pp 421-431.e7 (2020)
Summary: For decades, two fusion modes were thought to control hormone and transmitter release essential to life; one facilitates release via fusion pore dilation and flattening (full collapse), and the other limits release by closing a narrow fusion
Externí odkaz:
https://doaj.org/article/2e0c03cc3d67471682425f47514a1185
Autor:
Jie Yuan, Fan Zhang, Dennis Hallahan, Zhen Zhang, Liming He, Ling-Gang Wu, Meng You, Qin Yang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-14 (2018)
Abstract Background Reprogramming of cancers into normal-like tissues is an innovative strategy for cancer treatment. Recent reports demonstrate that defined factors can reprogram cancer cells into pluripotent stem cells. Glioblastoma multiforme (GBM
Externí odkaz:
https://doaj.org/article/5fd701e909604c48a50648796013e977