Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma

Autor: Bart Neyns, Lisa Zimmer, Caroline Robert, Celeste Lebbe, Olivier Michielin, Omid Hamid, Anne Zaremba, Oliver Klein, Ruth Plummer, Joanna Mangana, Paolo A Ascierto, Katharina C Kähler, Georgina V Long, Ryan Sullivan, Grant A McArthur, Michael Weichenthal, Egle Ramelyte, Meghan J Mooradian, Douglas B Johnson, Alexander Shoushtari, Christian U Blank, Judith M Versluis, Prachi Bhave, Claudia Trojanello, Lu Si, Inderjit Mehmi, Tasnia Ahmed, Alexander M Menzies, Adnan Khattak, Severine Roy, Matteo S Carlino, Paul C Lorigan, Clara Allayous, Rachel Roberts-Thomson, Florentia Dimitriou, Kathleen Batty, Thierry Lesimple, Serigne N Lo, Alexandre Wicky, Richard Heywood, Lena Tran, Anna Stansfeld, Julia K Schwarze, Andrea Maurichi, Hui-Ling Yeoh, Mario Santinami, Andrew M Haydon

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)

Background Acral melanoma is a rare melanoma subtype with poor prognosis. Importantly, these patients were not identified as a specific subgroup in the landmark melanoma trials involving ipilimumab and the anti-programmed cell death protein-1 (PD-1)

Externí odkaz: https://doaj.org/article/0b1c2b670e1e4ec1b95b97b6b085c47b

Immunometabolic and Lipidomic Markers Associated With the Frailty Index and Quality of Life in Aging HIV+ Men on Antiretroviral Therapy

Autor: Hui-Ling Yeoh, Allen C. Cheng, Catherine L. Cherry, Jacquelyn M. Weir, Peter J. Meikle, Jennifer F. Hoy, Suzanne M. Crowe, Clovis S. Palmer

Publikováno v: EBioMedicine, Vol 22, Iss C, Pp 112-121 (2017)

Chronic immune activation persists despite antiretroviral therapy (ART) in HIV+ individuals and underpins an increased risk of age-related co-morbidities. We assessed the Frailty Index in older HIV+ Australian men on ART. Immunometabolic markers on m

Externí odkaz: https://doaj.org/article/19fa67cdee264a1fbc99370d2273214b

Immune-related adverse events secondary to immunotherapy in oncology.

Autor: Hui-Ling Yeoh, Freilich, Karen, Voskoboynik, Mark, Moore, Maggie, Andrews, Miles C., Shackleton, Mark, Haydon, Andrew M.

Publikováno v: Australian Journal of General Practice; Jun2023, Vol. 52 Issue 6, p378-385, 8p

Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma

Autor: Prachi Bhave, Tasnia Ahmed, Serigne N Lo, Alexander Shoushtari, Anne Zaremba, Judith M Versluis, Joanna Mangana, Michael Weichenthal, Lu Si, Thierry Lesimple, Caroline Robert, Claudia Trojanello, Alexandre Wicky, Richard Heywood, Lena Tran, Kathleen Batty, Florentia Dimitriou, Anna Stansfeld, Clara Allayous, Julia K Schwarze, Meghan J Mooradian, Oliver Klein, Inderjit Mehmi, Rachel Roberts-Thomson, Andrea Maurichi, Hui-Ling Yeoh, Adnan Khattak, Lisa Zimmer, Christian U Blank, Egle Ramelyte, Katharina C Kähler, Severine Roy, Paolo A Ascierto, Olivier Michielin, Paul C Lorigan, Douglas B Johnson, Ruth Plummer, Celeste Lebbe, Bart Neyns, Ryan Sullivan, Omid Hamid, Mario Santinami, Grant A McArthur, Andrew M Haydon, Georgina V Long, Alexander M Menzies, Matteo S Carlino

Publikováno v: Bhave, P, Ahmed, T, Lo, S N, Shoushtari, A, Zaremba, A, Versluis, J M, Mangana, J, Weichenthal, M, Si, L, Lesimple, T, Robert, C, Trojanello, C, Wicky, A, Heywood, R, Tran, L, Batty, K, Dimitriou, F, Stansfeld, A, Allayous, C, Schwarze, J K, Mooradian, M J, Klein, O, Mehmi, I, Roberts-Thomson, R, Maurichi, A, Yeoh, H L, Khattak, A, Zimmer, L, Blank, C U, Ramelyte, E, Kähler, K C, Roy, S, Ascierto, P A, Michielin, O, Lorigan, P C, Johnson, D B, Plummer, R, Lebbe, C, Neyns, B, Sullivan, R, Hamid, O, Santinami, M, McArthur, G A, Haydon, A M, Long, G V, Menzies, A M & Carlino, M S 2022, ' Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma ', Journal for ImmunoTherapy of Cancer, vol. 10, no. 7, e004668 . https://doi.org/10.1136/jitc-2022-004668

BackgroundAcral melanoma is a rare melanoma subtype with poor prognosis. Importantly, these patients were not identified as a specific subgroup in the landmark melanoma trials involving ipilimumab and the anti-programmed cell death protein-1 (PD-1) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92b5a9d00012b0583c371b3485e31ff2
https://pubmed.ncbi.nlm.nih.gov/35793872

Pediatric Rheumatic Heart Disease in a Middle-Income Country: A Population-Based Study

Autor: Norazah Zahari, Si Ling Yeoh, Siva Rao Muniandy, Mohd Nizam Mat Bah

Publikováno v: Journal of Tropical Pediatrics. 68

Introduction Rheumatic heart disease (RHD), a debilitating complication from rheumatic fever, remains a problem in low- and middle-income countries. This study describes the incidence, prevalence, modifiable risk factors for severe RHD and immediate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31384b2dc6783c35a00c9879c7cd603a
https://doi.org/10.1093/tropej/fmac005