Výsledky vyhledávání - "Ling Y. Kong"

Inhibition of JAK2/STAT Signaling by Degrasyn through a Novel Mechanism

Autor: Geoffrey Bartholomeusz, Vaibhav Kapuria, Ling Y. Kong, William G. Bornmann, Nicholas J. Donato, Moshe Talpaz

Publikováno v: Blood. 108:3423-3423

Janus Kinase 2 (JAK2) is a cytokine receptor associated tyrosine kinase. Cytokine stimulation results in JAK2 activation and tyrosine phosphorylation of the cytokine receptor. Cytosolic SH2 domain containing proteins, such as the signal transducer an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f870ff7296981a72a53075e728faad33
https://doi.org/10.1182/blood.v108.11.3423.3423

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The SRC/ABL Inhibitor BMS-354825 Overcomes Resistance to Imatinib Mesylate in Chronic Myelogenous Leukemia Cells through Multiple Mechanisms

Autor: Moshe Talpaz, Ji Wu, Ling Y. Kong, Nicholas J. Donato, Francis Y. Lee

Publikováno v: Blood. 104:1989-1989

BCR-ABL is an oncogenic tyrosine kinase expressed in chronic myelogenous leukemia (CML) cells and is the main target of the tyrosine kinase inhibitor imatinib mesylate. Imatinib-based CML therapy induces hematological and cytogenetic remission in ear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::80ddafc7bf01bf3732ef92f54575ca02
https://doi.org/10.1182/blood.v104.11.1989.1989

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Targeting BCR-ABL and Its Downstream Signaling Cascade as Therapy for Chronic Myelogenous Leukemia

Autor: Moshe Talpaz, Feng Meng, Ling Y. Kong, Waldemar Priebe, Nicholas J. Donato, Ji Wu

Publikováno v: Blood. 104:2964-2964

BCR-ABL is an unregulated tyrosine kinase expressed as a consequence of chromosomal translocation in chronic myelogenous leukemia (CML). The tyrosine kinase activity of BCR-ABL activates signaling cascades that induce cytokine independence and transf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::194b45bdad18a5dff83d5792cb5b9884
https://doi.org/10.1182/blood.v104.11.2964.2964

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Mental stress inhibits the intimal fibromuscular proliferation through endogenous opioid system in the process of arterial remodeling

Autor: Yukiharu Nishimura, Hideyuki Hattori, Tsuyoshi Nakahashi, Masayuki Matsumoto, Kunimitsu Iwai, Kenichi Kawanishi, Shigeto Morimoto, Ling Y. Kong, Hiroshi Murai

Publikováno v: Journal of the American College of Cardiology. 41:298

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce77c47b4058efc3a87df2b590a1476
https://doi.org/10.1016/s0735-1097(03)82398-7

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