Zobrazeno 1 - 10
of 2 731
pro vyhledávání: '"Ling QI"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Endoplasmic reticulum (ER) homeostasis in the hypothalamus has been implicated in the pathogenesis of diet-induced obesity (DIO) and type 2 diabetes; however, the underlying molecular mechanism remain vague and debatable. Here we report that
Externí odkaz:
https://doaj.org/article/46a5d96103e24ca087db1e33dfdcc16a
Autor:
Yong Li, Wei‐Xin Liu, Ling Qi, Yin Li, Jun‐Feng Liu, Jian‐Hua Fu, Yong‐Tao Han, Wen‐Tao Fang, Zhen‐Tao Yu, Ke‐Neng Chen, You‐Sheng Mao
Publikováno v:
Thoracic Cancer, Vol 15, Iss 22, Pp 1705-1713 (2024)
Abstract Background To review the changes and survey on status quo of the surgical treatment for esophageal cancer in China. The differences in diagnosis and treatment for esophageal cancer among hospitals in different regions across China were also
Externí odkaz:
https://doaj.org/article/2137f4b5e76a4c839dbddd02d2cc6230
Autor:
Xiangzong Zeng, Yichen Wang, Min Dai, Wei Li, Qingtian Huang, Lingsha Qin, Yuquan Li, Yanwen Yan, Xiangjun Xue, Fang Yi, Wenhao Li, Langyu He, Qifa Liu, Ling Qi
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Myelodysplastic neoplasms (MDS) are myeloid neoplasms characterized by disordered differentiation of hematopoietic stem cells and a predisposition to acute myeloid leukemia (AML). The underline pathogenesis remains unclear. Method
Externí odkaz:
https://doaj.org/article/02fc2de121cc4f82b5b7b31bfc51f68e
Autor:
Cong Li, Shuanlong Che, Haotian Gong, Youde Ding, Yizhou Luo, Jianing Xi, Ling Qi, Guiying Zhang
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/428403cb5bf7421c977ee34dd7c282fb
Autor:
Jieyu Wang, Shixuan Wang, Zhiwen Xiao, Zhiwei Chen, Ling Qi, Baoquan Song, Jianxiang Wang, Fei Li
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/92c545d327f9464daa2b4549341eb1d9
Autor:
Qingtian Huang, Jie Yang, Jiaxing Zhang, Leyi Yao, Baoyi Jiang, Siyuan Du, Fengjin Li, Qian Peng, Lingsha Qin, Yanfen Wang, Ling Qi
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110496- (2024)
Summary: Pancreatic cancer is highly lethal with limited effective treatments. This study explores the therapeutic effects of eupalinolide B (EB) from Eupatorium lindleyanum DC on pancreatic cancer cells. Through cellular functional assays, we observ
Externí odkaz:
https://doaj.org/article/1d1cd3c57f2741a3a5c38889ee4695e9
Autor:
Cong Li, Shuanlong Che, Haotian Gong, Youde Ding, Yizhou Luo, Jianing Xi, Ling Qi, Guiying Zhang
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Vessel density within tumor tissues strongly correlates with tumor proliferation and serves as a critical marker for tumor grading. Recognition of vessel density by pathologists is subject to a strong inter-rater bias, thus limiting its prognostic va
Externí odkaz:
https://doaj.org/article/bfa75d25669b4251ba34e00f6fb3086d
Autor:
Michael J. Podolsky, Benjamin Kheyfets, Monika Pandey, Afaq H. Beigh, Christopher D. Yang, Carlos O. Lizama, Ritwik Datta, Liangguang L. Lin, Zhihong Wang, Paul J. Wolters, Michael T. McManus, Ling Qi, Kamran Atabai
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Accumulating evidence has implicated impaired extracellular matrix (ECM) clearance as a key factor in fibrotic disease. Despite decades of research elucidating the effectors of ECM clearance, relatively little is understood regarding the ups
Externí odkaz:
https://doaj.org/article/f4c1e0221b354d99b77f1b6eea76ff85
Autor:
Liangguang Leo Lin, Huilun Helen Wang, Brent Pederson, Xiaoqiong Wei, Mauricio Torres, You Lu, Zexin Jason Li, Xiaodan Liu, Hancheng Mao, Hui Wang, Linyao Elina Zhou, Zhen Zhao, Shengyi Sun, Ling Qi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract The SEL1L-HRD1 protein complex represents the most conserved branch of endoplasmic reticulum (ER)-associated degradation (ERAD). Despite recent advances in both mouse models and humans, in vivo evidence for the importance of SEL1L in the ERA
Externí odkaz:
https://doaj.org/article/014892729fb04bc09af72c00d188ae38
Autor:
Xiaoqiong Wei, You Lu, Liangguang Leo Lin, Chengxin Zhang, Xinxin Chen, Siwen Wang, Shuangcheng Alivia Wu, Zexin Jason Li, Yujun Quan, Shengyi Sun, Ling Qi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Endoplasmic reticulum-associated degradation (ERAD) plays indispensable roles in many physiological processes; however, the nature of endogenous substrates remains largely elusive. Here we report a proteomics strategy based on the intrinsic
Externí odkaz:
https://doaj.org/article/9af861f4006a4bc58054198a6fb20fa2