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Suppression of cytochrome P450 2E1 promoter activity by interferon-gamma and loss of response due to the -71GT nucleotide polymorphism of the CYP2E1*7B allele

Autor: Ling O. Qiu, Deborah M. Antonino-Green, Roland Valdes, Mark W. Linder

Publikováno v: The Journal of pharmacology and experimental therapeutics. 308(1)

The CYP2E1*7B allele is defined by two nucleotide sequence polymorphisms, -71G>T and -333T>A. The CYP2E1 promoter sequence flanking the -71G nucleotide is consistent with a gamma-interferon activated sequence. Inflammation and interferon (IFN)-gamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cd701b2c125312e595f859f3f16136
https://pubmed.ncbi.nlm.nih.gov/14566010

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