Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Ling Mei Kong"'
Autor:
Bing-Chao Yan, Wei-Guang Wang, Ling-Mei Kong, Jian-Wei Tang, Xue Du, Yan Li, Pema-Tenzin Puno
Publikováno v:
Journal of Fungi, Vol 8, Iss 5, p 543 (2022)
Cytochalasans from the endophytic fungi featured structure diversity. Our previous study has disclosed that cytochalasans from the endophytic fungus Phomopsis sp. shj2 exhibited an antimigratory effect. Further chemical investigation on Phomopsis sp.
Externí odkaz:
https://doaj.org/article/8550758b2ec84aea8873d04ed09fce07
Autor:
Ling-Mei Kong, Yan Li, Dongmei Fan, Shaohua Zhang, Xiaoman Ju, Yiying Zhu, Qihong Yang, Guifeng Su
Publikováno v:
Biochemical and Biophysical Research Communications. 562:21-28
Colorectal cancer stem cells (CCSCs) are implicated in colorectal tumor initiation, invasion, recurrence and treatment resistance, so elucidation of the mechanism underlying the cancer stem cells induction and development of drugs targeting CCSCs are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd3d270392f522a00385c079ab214e9
https://doi.org/10.1016/j.bbrc.2021.05.017
https://doi.org/10.1016/j.bbrc.2021.05.017
Autor:
Zhen-Nan Ye, Feng Yuan, Jie-Qing Liu, Xing-Rong Peng, Tao An, Xue Li, Ling-Mei Kong, Ming-Hua Qiu, Yan Li
Publikováno v:
Molecules, Vol 24, Iss 6, p 1146 (2019)
Deregulation of the Wnt signaling pathway leads to colorectal cancer progression. Natural dietary compounds serve as promising candidates for development as chemopreventive agents by suppressing the Wnt/β-catenin signaling pathway. Physalis peruvian
Externí odkaz:
https://doaj.org/article/5e83c73bfba14b51acda2ba5dd488669
Publikováno v:
Chinese Journal of Liquid Crystal and Displays. 36:123-133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2705f0568b961b13baaeca325dfa3509
https://doi.org/10.37188/cjlcd.2020-0286
https://doi.org/10.37188/cjlcd.2020-0286
Autor:
Li Zhang, Dong-Mei Wu, Haibo Du, Shuqun Zhang, Wei Sun, Yaping Li, Yan Li, Zhili Zuo, Ling-Mei Kong
Publikováno v:
Future Medicinal Chemistry. 11:1889-1906
Aim: Wee1 kinase plays a key role in the arrest of G2/M checkpoint that prevents mitotic entry in response to DNA damage. This work is to discover potent Wee1 inhibitors which can be considered valuable. Materials & Methods: Herein, Ensemble docking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acec706d29173a0ffacbf12fa21269f7
https://doi.org/10.4155/fmc-2019-0022
https://doi.org/10.4155/fmc-2019-0022
Autor:
Tao An, Ling-Mei Kong, Chunlei Yu, Hongyu Zhou, Juming Yan, Hongbin Zhang, Liang Gong, Huifang Zhu, Xiao-Liang Xu, Yaxiao Gong, Yan Li, Ying-Chao Li, Xiao-Dong Yang
Publikováno v:
Oncogene
Cancer stem cells (CSCs) have been implicated in metastasis, relapse, and therapeutic resistance of cancer, so successful cancer therapy may therefore require the development of drugs against CSCs or combining anti-CSCs drugs with conventional therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468cd414a340dbc57b9ba6b79fed1c1e
https://doi.org/10.1038/s41388-018-0674-5
https://doi.org/10.1038/s41388-018-0674-5
Autor:
Xiaoman Ju, Dongmei Fan, Shaohua Zhang, Ling-Mei Kong, Yiying Zhu, Yan Li, Qihong Yang, Guifeng Su
Publikováno v:
Molecules
Molecules, Vol 26, Iss 2059, p 2059 (2021)
Volume 26
Issue 7
Molecules, Vol 26, Iss 2059, p 2059 (2021)
Volume 26
Issue 7
Cancer has always been one of the most common malignant diseases in the world. Therefore, there is an urgent need to find potent agents with selective antitumor activity against cancer cells. It has been reported that antimicrobial peptides (AMPs) ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96aa3e35f4ab97779d2c000587767968
https://pubmed.ncbi.nlm.nih.gov/33916789
https://pubmed.ncbi.nlm.nih.gov/33916789
Autor:
Qihong Yang, Xue Li, Yan Li, Xiaoman Ju, Lin Chen, Tao An, Bicheng Cai, Ling-Mei Kong, Aizhu Duan
Publikováno v:
J Biol Chem
It has been well-established that the deubiquitinating enzyme ubiquitin-specific peptidase 7 (USP7) supports cancer growth by up-regulating multiple cellular pathways, including Wnt/β-catenin signaling. Therefore, considerable efforts are directed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f823abdbf6dd4797ec1971695689e155
https://europepmc.org/articles/PMC7076227/
https://europepmc.org/articles/PMC7076227/
Autor:
Yan Li, Xue Li, Jian-Wei Tang, Ling-Mei Kong, Tao An, Dongmei Fan, Pema-Tenzin Puno, Lin Chen
Publikováno v:
Biochemical and biophysical research communications. 525(2)
Microtubules are involved in celluar processes of movement, intracellular trafficking and mitosis, thus microtubule-targeting agents have been widely used in cancer therapy. Herein, we report isopenicin A, a novel meroterpenoid isolated from the plan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bac947a3f03ddbf730b09acf2bdb3f2
https://pubmed.ncbi.nlm.nih.gov/32089263
https://pubmed.ncbi.nlm.nih.gov/32089263
Publikováno v:
The Journal of Organic Chemistry. 83:15225-15235
Herein, we report an enantioselective synthesis of azepinones via the N-heterocyclic carbene (NHC) catalyzed [3+4] annulation reaction of isatin-derived enals and aurone-derived azadienes. The corresponding spirocyclic oxindole-benzofuroazepinones we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df9e0d807b22b2db415aa3708838681
https://doi.org/10.1021/acs.joc.8b02497
https://doi.org/10.1021/acs.joc.8b02497