Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ling Jing Jin"'
Autor:
Jun-Hui Su, Yao-Wen Hu, Yun-Ping Song, Yi Yang, Ruo-Yu Li, Kai-Ge Zhou, Ling Hu, Xin-Hua Wan, Fei Teng, Ling-Jing Jin
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionThe pedunculopontine nucleus (PPTg) is a vital interface between the basal ganglia and cerebellum, participating in modulation of the locomotion and muscle tone. Pathological changes of the PPTg have been reported in patients and animal m
Externí odkaz:
https://doaj.org/article/6069f7aa6fdd4d19bb7b86a66e4567a3
Autor:
Jing-Xing Zhang, Kai-Ge Zhou, Yan-Xin Yin, Ling-Jing Jin, Wei-Fang Tong, Jia Guo, Li-Hua Yu, Xian-Cheng Ye, Ming Jiang
Publikováno v:
Experimental Gerontology, Vol 171, Iss , Pp 112037- (2023)
Background: The excessive activation of the microglia leads to the release of inflammatory factors that contribute to neuronal cell loss and neurodegeneration in Parkinson's Disease (PD). Mesencephalic astrocyte-derived neurotrophic factor (MANF) tha
Externí odkaz:
https://doaj.org/article/bfbe207de8294bfe9151f9bdfae69d72
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Being a major component of the midbrain locomotion region, the pedunculopontine nucleus (PPN) is known to have various connections with the basal ganglia, the cerebral cortex, thalamus, and motor regions of the brainstem and spinal cord. Functionally
Externí odkaz:
https://doaj.org/article/e22ad728cdf04d4c90f6f9bfb707636f
Dynamic muscle paralytic effects of a novel botulinum toxin A free of neurotoxin‐associated proteins
Autor:
Wu‐chao Liu, Jun‐hui Su, Ya Feng, Xue‐rui Xiang, Li‐zhen Pan, Ying Liu, Lin Ma, Zhi‐yu Nie, Xue‐ping Zhang, Ling‐jing Jin
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 3, Pp n/a-n/a (2022)
Abstract Structurally, botulinum toxin type A (BTX‐A) is composed of neurotoxin and nontoxic complexing proteins (CPs), and the neurotoxin has the function of blocking acetylcholine release from the neuromuscular junction and therefore paralyzing m
Externí odkaz:
https://doaj.org/article/b1d6a3eb03bc498a9184e83a2c05110a
Autor:
Li‐Xi Li, Ying Liu, Jie‐Hong Huang, Yi Yang, You‐Gui Pan, Xiao‐Long Zhang, Li‐Zhen Pan, Ling‐Jing Jin
Publikováno v:
Clinical Genetics. 103:459-465
Autor:
Jing-Xing Zhang, Wei-Fang Tong, Ming Jiang, Kai-Ge Zhou, Xue-rui Xiang, Yi-jing He, Zhuo-yu Zhang, Qiang Guan, Ling-Jing Jin
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-19
Progressive accumulation of misfolded SNCA/α-synuclein is key to the pathology of Parkinson’s disease (PD). Drugs aiming at degrading SNCA may be an efficient therapeutic strategy for PD. Our previous study showed that mesencephalic astrocyte-deri
Autor:
Yan Yu, Jing‐Jing Li, Xiao‐Qian He, Zi‐Ying Lai, Rui Hao, Yu Qi, Dong‐Qing Cao, Ming Fu, Hong Ma, Qiu‐Chen Xie, Mu Sun, Zhi‐Li Huang, Ling‐Jing Jin, Hui‐hui Sun, Ning Lu, Rui Wang, Wing‐Ho Yung, Ying Huang
Publikováno v:
British Journal of Pharmacology. 179:2969-2985
Publikováno v:
Movement Disorders. 37:1099-1101
Publikováno v:
Mol Cell Biol
Charcot-Marie-Tooth type 4D (CMT4D) is an autosomal recessive demyelinating form of CMT characterized by progressive motor and sensory neuropathy. N-myc downstream regulated gene 1 (NDRG1) is the causative gene for CMT4D. Although more CMT4D cases ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa451b2c03795394b8be967a67742314
https://europepmc.org/articles/PMC9302083/
https://europepmc.org/articles/PMC9302083/
Autor:
Jing-Xing, Zhang, Wei-Fang, Tong, Ming, Jiang, Kai-Ge, Zhou, Xue-Rui, Xiang, Yi-Jing, He, Zhuo-Yu, Zhang, Qiang, Guan, Ling-Jing, Jin
Publikováno v:
Oxidative medicine and cellular longevity. 2022
Progressive accumulation of misfolded SNCA/