Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Ling Chu Chang"'
Publikováno v:
Journal of Biomedical Science, Vol 31, Iss 1, Pp 1-23 (2024)
Abstract A variety of cell death pathways play critical roles in the onset and progression of multiple diseases. Paraptosis, a unique form of programmed cell death, has gained significant attention in recent years. Unlike apoptosis and necrosis, para
Externí odkaz:
https://doaj.org/article/37670cf0f364400fa978c3d53a56fa9f
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Background Paraptosis is a programmed cell death characterized by cytoplasmic vacuolation, which has been explored as an alternative method for cancer treatment and is associated with cancer resistance. However, the mechanisms underlying the
Externí odkaz:
https://doaj.org/article/dcc7e46d203d44c4b08ea7f9851b1c08
Autor:
Sze‐Ching Wong, Chun‐Chieh Yeh, Xun‐Yu Zhang, Chih‐Ying Hsieh, Chia‐Chien Lo, Ting‐Ting Kuo, Ching‐Chan Lin, Chih‐Hua Chao, Jing‐Pei Liu, Ling‐Chu Chang, Lu‐Hai Wang, Yuh‐Pyng Sher
Publikováno v:
Molecular Oncology, Vol 17, Iss 8, Pp 1648-1665 (2023)
CUB domain‐containing protein 1 (CDCP1) contributes to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) resistance by regulating EGFR signaling pathways and is a potential target in lung cancer treatment. This study aims to i
Externí odkaz:
https://doaj.org/article/353ae90eeedf4b26a5791f7b425b5f6c
Autor:
Ching-Yun Hsieh, Ching-Chan Lin, Yu-Wen Huang, Jong-Hang Chen, Yung-An Tsou, Ling-Chu Chang, Chi-Chen Fan, Chen-Yuan Lin, Wei-Chao Chang
Publikováno v:
JCI Insight, Vol 7, Iss 23 (2022)
Docetaxel (DTX) combined with cisplatin and 5-fluorouracil has been used as induction chemotherapy for head and neck squamous cell carcinoma (HNSCC). However, the development of acquired resistance remains a major obstacle to treatment response. Tumo
Externí odkaz:
https://doaj.org/article/de49d4ba9cf44e3eb6dce6025accedfc
Autor:
Liang-Chih Liu, Yi-Chun Shen, Yuan-Liang Wang, Wan-Rong Wu, Ling-Chu Chang, Ya-Huey Chen, Chuan-Chun Lee, Shao-Chun Wang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The cGAS-STING axis is one of the key mechanisms guarding cells from pathogen invasion in the cytoplasmic compartment. Sensing of foreign DNA in the cytosol by the cGAS-STING axis triggers a stress cascade, culminating at stimulation of the protein k
Externí odkaz:
https://doaj.org/article/1ca77ec8e68b44fd9ab68d66b832f04a
Autor:
Chi-Chen Fan, Sheng-Ta Tsai, Chen-Yuan Lin, Ling-Chu Chang, Juan-Cheng Yang, Guan‐Yu Chen, Yuh-Pyng Sher, Shao-Chun Wang, Michael Hsiao, Wei‐Chao Chang
Publikováno v:
Redox Biology, Vol 34, Iss , Pp 101571- (2020)
Recurrence and metastasis remain the major cause of cancer mortality. Even for early-stage lung cancer, adjuvant chemotherapy yields merely slight increase to patient survival. EF-hand domain-containing protein D2 (EFHD2) has recently been implicated
Externí odkaz:
https://doaj.org/article/6417aba6fe7e4f2d9cc2fcb446d63216
Autor:
Hirohito Yamaguchi, Ling-Chu Chang, Olin Shih-Shin Chang, Yu-Fu Chen, Yu-Chun Hsiao, Chen-Shiou Wu, Mien-Chie Hung
Publikováno v:
International Journal of Biological Sciences; 2024, Vol. 20 Issue 1, p1-14, 14p
Publikováno v:
Cells, Vol 10, Iss 9, p 2401 (2021)
Heme oxygenases (HOs) act on heme degradation to produce carbon monoxide (CO), free iron, ferritin, and biliverdin. Upregulation of cellular HO-1 levels is signature of oxidative stress for its downstream effects particularly under pro-oxidative stat
Externí odkaz:
https://doaj.org/article/abcd05c3eaa543468d16ec2eafd5e64c
Autor:
null Sze‐Ching Wong, null Chun‐Chieh Yeh, null Xun‐Yu Zhang, null Chih‐Ying Hsieh, null Chia‐Chien Lo, null Ting‐Ting Kuo, null Ching‐Chan Lin, null Chih‐Hua Chao, null Jing‐Pei Liu, null Ling‐Chu Chang, null Lu‐Hai Wang, null Yuh‐Pyng Sher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d591f312090081d63a1d707501ebfe9
https://doi.org/10.1002/1878-0261.13429/v2/response1
https://doi.org/10.1002/1878-0261.13429/v2/response1
Publikováno v:
Animals, Vol 10, Iss 11, p 1969 (2020)
Past studies regarding to insulin secretion and glucose disposal in chickens were focused on rapidly growing juvenile broilers and may not reflect glucose/insulin physiology in adulthood. The study aimed to assess insulin secretion and glucose dispos
Externí odkaz:
https://doaj.org/article/fe827b000fbb45e284b0aeec15c40d80