Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Ling‐Yuh Huw"'
Autor:
Monica E. Susilo, Chi‐Chung Li, Kapil Gadkar, Genevive Hernandez, Ling‐Yuh Huw, Jin Y. Jin, Shen Yin, Michael C. Wei, Saroja Ramanujan, Iraj Hosseini
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 7, Pp 1134-1148 (2023)
Abstract Phase I oncology clinical trials often comprise a limited number of patients representing different disease subtypes who are divided into cohorts receiving treatment(s) at different dosing levels and schedules. Here, we leverage a previously
Externí odkaz:
https://doaj.org/article/2bc7d8bf72c444f492e191b7c0cbf612
Autor:
Radia M. Johnson, Xueping Qu, Chu-Fang Lin, Ling-Yuh Huw, Avinashnarayan Venkatanarayan, Ethan Sokol, Fang-Shu Ou, Nnamdi Ihuegbu, Oliver A. Zill, Omar Kabbarah, Lisa Wang, Richard Bourgon, Felipe de Sousa e Melo, Chris Bolen, Anneleen Daemen, Alan P. Venook, Federico Innocenti, Heinz-Josef Lenz, Carlos Bais
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
ARID1A is an epigenetic regulator mutated in approximately 5% of non-hypermutated colorectal cancer tumors, however, its relationship with treatment response remains to be explored. Here, the authors suggest that ARID1A mutations may confer intrinsic
Externí odkaz:
https://doaj.org/article/4488b89ca7bf43bdb1d09041a86d2a0c
Autor:
Adam J. Olszewski, L. Elizabeth Budde, Julio Chavez, Nilanjan Ghosh, Manali Kamdar, Izidore S. Lossos, Catherine Diefenbach, Waleed Sabry, Kathleen Dorritie, Ling-Yuh Huw, Song Pham, Ting Jia, Hao Wu, Iris To, Michael C. Wei, Sarit Assouline
Publikováno v:
Blood. 140:3757-3759
Autor:
Mark R. Lackner, Craig Cummings, Steven Gendreau, Ling-Yuh Huw, Rebecca Suttmann, May M.Y. Liang-Chu, Mamie Yu, Junko Aimi, Charles Baudo, Vidushi Kapoor, Kathryn E. Yoh, Jill M. Spoerke, Ching-Wei Chang, Xiaoji Chen
cfDNA tumor fraction dynamics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225eab50b3122ce04587e260653b6df9
https://doi.org/10.1158/1078-0432.22474475.v1
https://doi.org/10.1158/1078-0432.22474475.v1
Autor:
Yulei Wang, Carlos Bais, Lukas C. Amler, Ling Fu, Mark R. Lackner, Ling-Yuh Huw, Eloisa Fuentes, Shan Lu, Christina Rabe, Younjeong Choi, Yuanyuan Xiao, Ron Firestein, Yinghui Guan, Lisa Ryner
Purpose: Up to one third of ovarian cancer patients are intrinsically resistant to platinum-based treatment. However, predictive and therapeutic strategies are lacking due to a poor understanding of the underlying molecular mechanisms. This study aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443ebbbb567052a3114c0f2ed80b522f
https://doi.org/10.1158/1078-0432.c.6523293
https://doi.org/10.1158/1078-0432.c.6523293
Autor:
Mark R. Lackner, Craig Cummings, Steven Gendreau, Ling-Yuh Huw, Rebecca Suttmann, May M.Y. Liang-Chu, Mamie Yu, Junko Aimi, Charles Baudo, Vidushi Kapoor, Kathryn E. Yoh, Jill M. Spoerke, Ching-Wei Chang, Xiaoji Chen
Purpose:We developed a method to monitor copy number variations (CNV) in plasma cell-free DNA (cfDNA) from patients with metastatic squamous non–small cell lung cancer (NSCLC). We aimed to explore the association between tumor-derived cfDNA and cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31eb86c6dd4fbb499599b927038e7b6c
https://doi.org/10.1158/1078-0432.c.6528800
https://doi.org/10.1158/1078-0432.c.6528800
Autor:
Mark R. Lackner, Lukas C. Amler, Xiaolan Hu, Guy Cavet, Elizabeth Luis, Gail D. Lewis Phillips, Leanne Berry, Fiona Zhong, Ling-Yuh Huw, Heidi Savage, Carol O'Brien, Jiping Zha
Commentary on this Article from Molecular predictors of response to a humanized anti–insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bd0be75b8efc2db9b2c2e4d98a9afc0
https://doi.org/10.1158/1535-7163.22485912
https://doi.org/10.1158/1535-7163.22485912
Autor:
Mark R. Lackner, Lukas C. Amler, Xiaolan Hu, Guy Cavet, Elizabeth Luis, Gail D. Lewis Phillips, Leanne Berry, Fiona Zhong, Ling-Yuh Huw, Heidi Savage, Carol O'Brien, Jiping Zha
The insulin-like growth factor-I receptor (IGF-IR) pathway is required for the maintenance of the transformed phenotype in neoplastic cells and hence has been the subject of intensive drug discovery efforts. A key aspect of successful clinical develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e442f70eabbe3ad26b8a94c3d2280b
https://doi.org/10.1158/1535-7163.c.6532137.v1
https://doi.org/10.1158/1535-7163.c.6532137.v1
Autor:
Mark R. Lackner, Lukas C. Amler, Xiaolan Hu, Guy Cavet, Elizabeth Luis, Gail D. Lewis Phillips, Leanne Berry, Fiona Zhong, Ling-Yuh Huw, Heidi Savage, Carol O'Brien, Jiping Zha
Supplementary Figures 1-7 from Molecular predictors of response to a humanized anti–insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efe9e774c248097dddf48199ee8d5a08
https://doi.org/10.1158/1535-7163.22485909.v1
https://doi.org/10.1158/1535-7163.22485909.v1
Autor:
Yulei Wang, Carlos Bais, Lukas C. Amler, Ling Fu, Mark R. Lackner, Ling-Yuh Huw, Eloisa Fuentes, Shan Lu, Christina Rabe, Younjeong Choi, Yuanyuan Xiao, Ron Firestein, Yinghui Guan, Lisa Ryner
Supplementary Tables S1-S7. This is a multi-"tabbed" Excel file containing the supplementary data of the manuscript and includes a "Summary" tab with descriptions/captions for the enclosed data sheets. They are as follows: Supplementary Table S1: 800
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fab2fa44fb86c3500e04345f3270e99
https://doi.org/10.1158/1078-0432.22456386.v1
https://doi.org/10.1158/1078-0432.22456386.v1