Zobrazeno 1 - 10
of 909
pro vyhledávání: '"Ling‐Yi Kong"'
Autor:
Kai-Bo Wang, Yushuang Liu, Jinzhu Li, Chengmei Xiao, Yingying Wang, Wei Gu, Yipu Li, Yuan-Zheng Xia, Tingdong Yan, Ming-Hua Yang, Ling-Yi Kong
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The G-quadruplex formed in KRAS oncogene promoter (KRAS-G4) is a transcriptional modulator and amenable to small molecule targeting. Herein, the authors report the NMR solution structures of a bulge-containing KRAS-G4 that bound to two small molecule
Externí odkaz:
https://doaj.org/article/3a3ab16b284641808c7b23a21ff63551
Autor:
Yi‐Feng Liu, Kai Han, Dan‐Ni Peng, Ling‐Yi Kong, Yu Su, Hong‐Wei Li, Hai‐Yan Hu, Jia‐Yang Li, Hong‐Rui Wang, Zhi‐Qiang Fu, Qiang Ma, Yan‐Fang Zhu, Rui‐Ren Tang, Shu‐Lei Chou, Yao Xiao, Xiong‐Wei Wu
Publikováno v:
InfoMat, Vol 5, Iss 6, Pp n/a-n/a (2023)
Abstract Sodium‐ion batteries (SIBs) are considered as a low‐cost complementary or alternative system to prestigious lithium‐ion batteries (LIBs) because of their similar working principle to LIBs, cost‐effectiveness, and sustainable availabi
Externí odkaz:
https://doaj.org/article/a8640eaa2eac4d8c94aebfc54e3506b5
Autor:
Liu-Liu Yuan, Zhong Chen, Jian Qin, Cheng-Jiao Qin, Jing Bian, Rui-Fang Dong, Tang-Bo Yuan, Yi-Ting Xu, Ling-Yi Kong, Yuan-Zheng Xia
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Skeletal undifferentiated pleomorphic sarcoma (SUPS) is an invasive pleomorphic soft tissue sarcoma with a high degree of malignancy and poor prognosis. It is prone to recur and metastasize. The tumor microenvironment (TME) and the pathophysiology of
Externí odkaz:
https://doaj.org/article/24216b7df9c541af9c548a42eb1419d0
Publikováno v:
Natural Products and Bioprospecting, Vol 11, Iss 1, Pp 81-86 (2020)
Abstract Four new limonoids, toonayunnanaes F − I (1 − 4), and six known compounds (5 − 10) were isolated from the barks of Toona ciliata. Their structures were elucidated by thoroughly analyzing of NMR and HRMS data, and single-crystal X-ray d
Externí odkaz:
https://doaj.org/article/fca60fb0e6314274bc4d3c675eb97b2f
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Redirection of the TCA cycle intermediate aconitate to itaconate production has anti-inflammatory effects. Here the authors show that the itaconate derivative 4-octyl-itaconate is anti-inflammatory partly as a result of inhibiting GAPDH enzymatic act
Externí odkaz:
https://doaj.org/article/2b66b3e7c6704dc1a4818c1e7d684e87
Autor:
Jia-Jia Wu, Ting Ma, Zhi-Min Wang, Wen-Jun Xu, Xue-Lian Yang, Jian-Guang Luo, Ling-Yi Kong, Xiao-Bing Wang
Publikováno v:
Journal of Functional Foods, Vol 28, Iss , Pp 205-214 (2017)
A new peroxide of xanthone (1), together with five analogues (2–6), was obtained from horseradish peroxidase (HRP) catalysed biotransformation of α-mangostin. In order to increase the yield of compound 1, the environmental pH was succinctly adjust
Externí odkaz:
https://doaj.org/article/0bcb9bc7d1414c1eaaf63ca5e37c1927
Publikováno v:
Integrative Cancer Therapies, Vol 18 (2019)
Pharbitidis Semen has worldwide recognition in traditional medicine for the treatment of several illnesses apart from its purgative properties, and it is also reported to show anticancer effect. However, limited pharmacological studies are available
Externí odkaz:
https://doaj.org/article/7bd7b1e6a11949039cb11efa8bced55f
Publikováno v:
World Journal of Traditional Chinese Medicine, Vol 2, Iss 1, Pp 26-41 (2016)
Genus Alpinia consists of over 250 species, which are widely distributed in south and southeast Asia. Many plants of genus Alpinia have been used for thousands of years to treat digestive system diseases and as anti-inflammatory drugs. Phytochemical
Externí odkaz:
https://doaj.org/article/5d34b8b43b53428fb04f814bef5f4f0b
Publikováno v:
Journal of Functional Foods, Vol 19, Iss , Pp 141-154 (2015)
Water spinach (I. aquatica) is one of the common green leafy vegetables used in Asia. In a continuing chemical investigation on the cytotoxic resin glycosides from water spinach, eight new resin glycosides, Aquaterins XII–XIX (1–8), were isolated
Externí odkaz:
https://doaj.org/article/10f34a985cc14ae9956089ac4fcebb6c
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Huang-Lian-Jie-Du-Decoction, a traditional Chinese formula, has been reported to protect liver from various injuries. Two cholestasis models of rats induced by thioacetamide and by bile duct ligation were established and treated with Huang-Lian-Jie-D
Externí odkaz:
https://doaj.org/article/1906349e8f2b4d4eb0118605ee6ad84e