Výsledky vyhledávání - "Ling‐Min Kong"

Akademický článek

HMMR alleviates endoplasmic reticulum stress by promoting autophagolysosomal activity during endoplasmic reticulum stress‐driven hepatocellular carcinoma progression

Autor: Lin He, Hao Li, Can Li, Ze‐Kun Liu, Meng Lu, Ren‐Yu Zhang, Dong Wu, Ding Wei, Jie Shao, Man Liu, Hao‐Lin Wei, Cong Zhang, Zhe Wang, Ling‐Min Kong, Zhi‐Nan Chen, Huijie Bian

Publikováno v: Cancer Communications, Vol 43, Iss 9, Pp 981-1002 (2023)

Abstract Background The mechanism of hepatitis B virus (HBV)‐induced carcinogenesis remains an area of interest. The accumulation of hepatitis B surface antigen in the endoplasmic reticulum (ER) of hepatocytes stimulates persistent ER stress. Activ

Externí odkaz: https://doaj.org/article/1897dcbb12144a1ba7353c0c89c8b9a8

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Akademický článek

EYA2 suppresses the progression of hepatocellular carcinoma via SOCS3-mediated blockade of JAK/STAT signaling

Autor: Ze-Kun Liu, Can Li, Ren-Yu Zhang, Ding Wei, Yu-Kui Shang, Yu-Le Yong, Ling-Min Kong, Nai-Shan Zheng, Ke Liu, Meng Lu, Man Liu, Cai-Xia Hu, Xiao-Zhen Yang, Zhi-Nan Chen, Huijie Bian

Publikováno v: Molecular Cancer, Vol 20, Iss 1, Pp 1-18 (2021)

Abstract Background Somatic mutations are involved in hepatocellular carcinoma (HCC) progression, but the genetic mechanism associated to hepatocarcinogenesis remains poorly understood. We report that Eyes absent homolog 2 (EYA2) suppresses the HCC p

Externí odkaz: https://doaj.org/article/45fb30bc5bea4924866c9fcdb113aeed

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Akademický článek

Combining a CDK4/6 Inhibitor With Pemetrexed Inhibits Cell Proliferation and Metastasis in Human Lung Adenocarcinoma

Autor: Yuan Ke, Cheng-Gong Liao, Zheng-Qing Zhao, Xiao-Min Li, Rong-Jie Lin, Long Yang, He-Long Zhang, Ling-Min Kong

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

BackgroundRecent clinical trials of cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) in human lung adenocarcinoma (LUAD) have not achieved satisfactory results. The disappointing results of single-drug treatments have prompted studies about synergist

Externí odkaz: https://doaj.org/article/10d9e4cd1e7c4d8095ed11b76c68b3f7

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Akademický článek

Autor: Ze-Kun Liu, Ke-Fei Wu, Ren-Yu Zhang, Ling-Min Kong, Run-Ze Shang, Jian-Jun Lv, Can Li, Meng Lu, Yu-Le Yong, Cong Zhang, Nai-Shan Zheng, Yan-Hong Li, Zhi-Nan Chen, Huijie Bian, Ding Wei

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Pyroptosis is an inflammatory form of programmed cell death that is involved in various cancers, including hepatocellular carcinoma (HCC). Long non-coding RNAs (lncRNAs) were recently verified as crucial mediators in the regulation of pyroptosis. How

Externí odkaz: https://doaj.org/article/eb40d2d652b0417b8487c1678422026d

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