Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Linette Rodriguez"'
Autor:
Ella Fung, Liya Kang, Diana Sapashnik, Susan Benard, Annette Sievers, Yan Liu, Guoying Yan, Jing Zhou, Linette Rodriguez, Weijun Ma, Wayne R. Stochaj, Edward LaVallie, Liliana Wroblewska, Kerry Kelleher, Amy Tam, Olivier Bezy, Danna Breen, Jeffrey R. Chabot, Tao He, Laura Lin, Zhidan Wu, Lidia Mosyak
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract GDF15 is a distant TGF-β family member that induces anorexia and weight loss. Due to its function, GDF15 has attracted attention as a potential therapeutic for the treatment of obesity and its associated metabolic diseases. However, the pha
Externí odkaz:
https://doaj.org/article/8c6c1df6d01f479188c806163a2d9e3d
Autor:
James R Apgar, Amy S P Tam, Rhady Sorm, Sybille Moesta, Amy C King, Han Yang, Kerry Kelleher, Denise Murphy, Aaron M D'Antona, Guoying Yan, Xiaotian Zhong, Linette Rodriguez, Weijun Ma, Darren E Ferguson, Gregory J Carven, Eric M Bennett, Laura Lin
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232713 (2020)
For an antibody to be a successful therapeutic many competing factors require optimization, including binding affinity, biophysical characteristics, and immunogenicity risk. Additional constraints may arise from the need to formulate antibodies at hi
Externí odkaz:
https://doaj.org/article/cc94f4a62bcb4df1920dad454aac1825
