AMICI: High-Performance Sensitivity Analysis for Large Ordinary Differential Equation Models

Autor: Fröhlich, Fabian, Weindl, Daniel, Schälte, Yannik, Pathirana, Dilan, Paszkowski, Łukasz, Lines, Glenn Terje, Stapor, Paul, Hasenauer, Jan

Ordinary differential equation models facilitate the understanding of cellular signal transduction and other biological processes. However, for large and comprehensive models, the computational cost of simulating or calibrating can be limiting. AMICI

Externí odkaz: http://arxiv.org/abs/2012.09122

NEIL3-deficient bone marrow displays decreased hematopoietic capacity and reduced telomere length

Autor: Karlsen, Tom Rune, Olsen, Maria Belland, Kong, Xiang Yi, Yang, Kuan, Quiles-Jiménez, Ana M T, Kroustallaki, Pinelopi, Holm, Sverre, Lines, Glenn Terje, Aukrust, Pål, Skarpengland, Tonje, Bjørås, Magnar, Dahl, Tuva Børresdatter, Nilsen, Hilde, Gregersen, Ida, Halvorsen, Bente

Externí odkaz: https://hdl.handle.net/11250/3033041

On the frequency of automaticity during ischemia in simulations based on stochastic perturbations of the Luo–Rudy 1 model

Autor: Linge, Svein Ohm, Lines, Glenn Terje, Sundnes, Joakim, Tveito, Aslak

Publikováno v: In Computers in Biology and Medicine 2008 38(11):1218-1227

Ryanodine receptor dispersion disrupts Ca2+ release in failing cardiac myocytes

Autor: Kolstad, Terje R Selnes, Brink, Jonas van Den, Macquaide, Niall, Lunde, Per Kristian, Frisk, Michael, Aronsen, Jan Magnus, Norden, Einar Sjaastad, Cataliotti, Alessandro, Sjaastad, Ivar, Sejersted, Ole M, Edwards, Andrew, Lines, Glenn Terje, Louch, William Edward

Publikováno v: Kolstad, Terje R Selnes Brink, Jonas van Den Macquaide, Niall Lunde, Per Kristian Frisk, Michael Aronsen, Jan Magnus Norden, Einar Sjaastad Cataliotti, Alessandro Sjaastad, Ivar Sejersted, Ole M Edwards, Andrew Lines, Glenn Terje Louch, William Edward . Ryanodine receptor dispersion disrupts Ca2+ release in failing cardiac myocytes. eLIFE. 2018, 7
eLIFE

Externí odkaz: http://hdl.handle.net/10852/67967
https://www.duo.uio.no/bitstream/handle/10852/67967/1/elife-39427-v2.pdf

Pleiotropic effects of schizophrenia-associated genetic variants in neuron firing and cardiac pacemaking revealed by computational modeling

Autor: Mäki-Marttunen, Tuomo, Lines, Glenn Terje, Edwards, Andrew G, Tveito, Aslak, Dale, Anders M., Einevoll, Gaute, Andreassen, Ole Andreas

Publikováno v: Mäki-Marttunen, Tuomo Lines, Glenn Terje Edwards, Andrew G Tveito, Aslak Dale, Anders M. Einevoll, Gaute Andreassen, Ole Andreas . Pleiotropic effects of schizophrenia-associated genetic variants in neuron firing and cardiac pacemaking revealed by computational modeling. Translational psychiatry. 2017
Translational psychiatry

Externí odkaz: http://hdl.handle.net/10852/64140
https://www.duo.uio.no/bitstream/handle/10852/64140/1/maki-marttunen2017pleiotropic.pdf