Zobrazeno 1 - 10
of 3 199
pro vyhledávání: '"Lineage tracing"'
Autor:
Kumi Morikawa, Akira Nagasaki, Lue Sun, Eihachiro Kawase, Tatsuhiko Ebihara, Yasuaki Shirayoshi
Publikováno v:
FEBS Open Bio, Vol 14, Iss 11, Pp 1888-1898 (2024)
Establishing a highly efficient photoactivatable Cre recombinase PA‐Cre3.0 can allow spatiotemporal control of Cre recombinase activity. This technique may help to elucidate cell lineages, as well as facilitate gene and cell function analysis durin
Externí odkaz:
https://doaj.org/article/fea6750b912349d096dcb4d2e9258167
Autor:
Marius Lange, Zoe Piran, Michal Klein, Bastiaan Spanjaard, Dominik Klein, Jan Philipp Junker, Fabian J. Theis, Mor Nitzan
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-38 (2024)
Abstract Simultaneous profiling of single-cell gene expression and lineage history holds enormous potential for studying cellular decision-making. Recent computational approaches combine both modalities into cellular trajectories; however, they canno
Externí odkaz:
https://doaj.org/article/f18898a9969744c8a28f8aa670e6fcef
Autor:
Hyun Ji Kim, Dong Woo Seo, Jaewon Shim, Jun-Seok Lee, Sang-Hyun Choi, Dong-Hoon Kim, Seok Jun Moon, Han-Sung Jung, Yong Taek Jeong
Publikováno v:
Animal Cells and Systems, Vol 28, Iss 1, Pp 353-366 (2024)
Taste buds, the neuroepithelial organs responsible for the detection of gustatory stimuli in the oral cavity, arise from stem/progenitor cells among nearby basal keratinocytes. Using genetic lineage tracing, Lgr5 and Lgr6 were suggested as the specif
Externí odkaz:
https://doaj.org/article/bffb24c4fea0407db0d192426fcc8fc6
Autor:
Toshihide Mizoguchi
Publikováno v:
Japanese Dental Science Review, Vol 60, Iss , Pp 109-119 (2024)
Bone tissue provides structural support for our bodies, with the inner bone marrow (BM) acting as a hematopoietic organ. Within the BM tissue, two types of stem cells play crucial roles: mesenchymal stem cells (MSCs) (or skeletal stem cells) and hema
Externí odkaz:
https://doaj.org/article/cb6b5dfa805441a6ba35a2adcc717353
Autor:
Muhammad Ashfaq Khan, Julian Fischer, Leon Harrer, Fabian Schwiering, Dieter Groneberg, Andreas Friebe
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The combination of lineage tracing and immunohistochemistry has helped to identify subpopulations and fate of hepatic stellate cells (HSC) in murine liver. HSC are sinusoidal pericytes that act as myofibroblast precursors after liver injury.
Externí odkaz:
https://doaj.org/article/091f823e807f4d8987d870c715dd14b5
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Engineered mammalian cells are key for biotechnology by enabling broad applications ranging from in vitro model systems to therapeutic biofactories. Engineered cell lines exist as a population containing sub-lineages of cell clones that exhi
Externí odkaz:
https://doaj.org/article/a91ecfa1d35f43a6bfa4a6c090452d3f
Publikováno v:
MedComm, Vol 5, Iss 10, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/25b99d65210b4cfebc314c23a797d9f1
Autor:
Fei Chen, Kunshan Zhang, Minjun Wang, Zhiying He, Bing Yu, Xin Wang, Xinghua Pan, Yuping Luo, Shoujia Xu, Joseph T.Y. Lau, Chunsheng Han, Yufang Shi, Yi E. Sun, Siguang Li, Yi‐Ping Hu
Publikováno v:
Advanced Science, Vol 11, Iss 33, Pp n/a-n/a (2024)
Abstract Understanding the liver stem cells (LSCs) holds great promise for new insights into liver diseases and liver regeneration. However, the heterogenicity and plasticity of liver cells have made it controversial. Here, by employing single‐cell
Externí odkaz:
https://doaj.org/article/8529960fe08c4012bfdbf1dc61c5d470
Autor:
Ewa Bielczyk-Maczynska
Publikováno v:
Adipocyte, Vol 13, Iss 1 (2024)
Dedifferentiated adipose tissue (DFAT) has been proposed as a promising source of patient-specific multipotent progenitor cells (MPPs). During induced dedifferentiation, adipocytes exhibit profound gene expression and cell morphology changes. However
Externí odkaz:
https://doaj.org/article/a9adb2de0cb84822b9e229d0c42fc649
Publikováno v:
eLife, Vol 13 (2024)
B-cell repertoires are characterized by a diverse set of receptors of distinct specificities generated through two processes of somatic diversification: V(D)J recombination and somatic hypermutations. B-cell clonal families stem from the same V(D)J r
Externí odkaz:
https://doaj.org/article/e9640bc963ad4785be72a3e83d8576f9