Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Line S Reinert"'
Autor:
Rafael Bayarri-Olmos, Laust Bruun Johnsen, Manja Idorn, Line S Reinert, Anne Rosbjerg, Søren Vang, Cecilie Bo Hansen, Charlotte Helgstrand, Jais Rose Bjelke, Theresa Bak-Thomsen, Søren R Paludan, Peter Garred, Mikkel-Ole Skjoedt
Publikováno v:
eLife, Vol 10 (2021)
The alpha/B.1.1.7 SARS-CoV-2 lineage emerged in autumn 2020 in the United Kingdom and transmitted rapidly until winter 2021 when it was responsible for most new COVID-19 cases in many European countries. The incidence domination was likely due to a f
Externí odkaz:
https://doaj.org/article/0dacfd22c5c844a6adf835fea181b896
Autor:
Anna Gebhardt, Valter Bergant, Daniel Schnepf, Markus Moser, Arno Meiler, Dieudonnée Togbe, Claire Mackowiak, Line S Reinert, Søren R Paludan, Bernhard Ryffel, Alexey Stukalov, Peter Staeheli, Andreas Pichlmair
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008155 (2019)
Cellular response to environmental challenges requires immediate and precise regulation of transcriptional programs. During viral infections, this includes the expression of antiviral genes that are essential to combat the pathogen. Transcribed mRNAs
Externí odkaz:
https://doaj.org/article/2f2f0378c45148fa99debb5c174e921a
Autor:
Morten K Skouboe, Alice Knudsen, Line S Reinert, Cedric Boularan, Thierry Lioux, Eric Perouzel, Martin K Thomsen, Søren R Paludan
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1006976 (2018)
In recent years, there has been an increasing interest in immunomodulatory therapy as a means to treat various conditions, including infectious diseases. For instance, Toll-like receptor (TLR) agonists have been evaluated for treatment of genital her
Externí odkaz:
https://doaj.org/article/4ef01a80f8f8483bafe8e9514f8f5aa7
Autor:
Ensieh Farahani, Line S. Reinert, Ryo Narita, Manutea C. Serrero, Morten Kelder Skouboe, Demi van der Horst, Sonia Assil, Baocun Zhang, Marie B. Iversen, Eugenio Gutierrez, Hossein Hazrati, Mogens Johannsen, David Olagnier, Reiner Kunze, Mark Denham, Trine H. Mogensen, Michael Lappe, Søren R. Paludan
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113792- (2024)
Summary: Pattern recognition receptors (PRRs) induce host defense but can also induce exacerbated inflammatory responses. This raises the question of whether other mechanisms are also involved in early host defense. Using transcriptome analysis of di
Externí odkaz:
https://doaj.org/article/44f664b9af4a437aa62a40c3c3077e62
Autor:
Zaid Taha, Rozanne Arulanandam, Glib Maznyi, Elena Godbout, Madalina E. Carter-Timofte, Naziia Kurmasheva, Line S. Reinert, Andrew Chen, Mathieu J.F. Crupi, Stephen Boulton, Geneviève Laroche, Alexandra Phan, Reza Rezaei, Nouf Alluqmani, Anna Jirovec, Alexandra Acal, Emily E.F. Fekete, Ragunath Singaravelu, Julia Petryk, Manja Idorn, Kyle G. Potts, Hayley Todesco, Cini John, Douglas J. Mahoney, Carolina S. Ilkow, Patrick Giguère, Tommy Alain, Marceline Côté, Søren R. Paludan, David Olagnier, John C. Bell, Taha Azad, Jean-Simon Diallo
Publikováno v:
Taha, Z, Arulanandam, R, Maznyi, G, Godbout, E, Carter-Timofte, M E, Kurmasheva, N, Reinert, L S, Chen, A, Crupi, M J F, Boulton, S, Laroche, G, Phan, A, Rezaei, R, Alluqmani, N, Jirovec, A, Acal, A, Brown, E E F, Singaravelu, R, Petryk, J, Idorn, M, Potts, K G, Todesco, H, John, C, Mahoney, D J, Ilkow, C S, Giguère, P, Alain, T, Côté, M, Paludan, S R, Olagnier, D, Bell, J C, Azad, T & Diallo, J-S 2022, ' Identification of FDA-approved bifonazole as a SARS-CoV-2 blocking agent following a bioreporter drug screen ', Molecular Therapy, vol. 30, no. 9, pp. 2998-3016 . https://doi.org/10.1016/j.ymthe.2022.04.025
We established a split nanoluciferase complementation assay to rapidly screen for inhibitors that interfere with binding of the receptor binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein with
Autor:
Ronald B. Gartenhaus, Huili He, Kurtis E. Bachman, Michele Vitolo, Krystyna Mazan-Mamczarz, Suvobroto Nandi, Bo Shi, Line S. Reinert
MCT-1 is an oncogene that was initially identified in a human T cell lymphoma and has been shown to induce cell proliferation as well as activate survival-related pathways. MCT-1 contains the PUA domain, a recently described RNA-binding domain that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b2a3df72522381186e79dc2da18cc0
https://doi.org/10.1158/0008-5472.c.6494619
https://doi.org/10.1158/0008-5472.c.6494619
Autor:
Ronald B. Gartenhaus, Huili He, Kurtis E. Bachman, Michele Vitolo, Krystyna Mazan-Mamczarz, Suvobroto Nandi, Bo Shi, Line S. Reinert
Supplementary Figure Legend and Table 1 from MCT-1 Protein Interacts with the Cap Complex and Modulates Messenger RNA Translational Profiles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe1067a90ddd289e0465615f397e2f4
https://doi.org/10.1158/0008-5472.22365279.v1
https://doi.org/10.1158/0008-5472.22365279.v1
Autor:
Ronald B. Gartenhaus, Huili He, Kurtis E. Bachman, Michele Vitolo, Krystyna Mazan-Mamczarz, Suvobroto Nandi, Bo Shi, Line S. Reinert
Supplementary Figure 1 from MCT-1 Protein Interacts with the Cap Complex and Modulates Messenger RNA Translational Profiles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b57deebf282baa14d2ba5d3947f4887
https://doi.org/10.1158/0008-5472.22365282.v1
https://doi.org/10.1158/0008-5472.22365282.v1
Autor:
Stefanie Fruhwürth, Line S. Reinert, Carl Öberg, Marcelina Sakr, Marcus Henricsson, Henrik Zetterberg, Søren R. Paludan
Immunological control of viral infection in the brain is essential for immediate protection, but also for long-term maintenance of brain integrity. As the primary resident immune cell of the brain, microglia protect against viral infections through k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf6bf094beb3f56ca5e4f170b068dc11
https://doi.org/10.1101/2023.03.16.532882
https://doi.org/10.1101/2023.03.16.532882
Autor:
Georgios Katzilieris-Petras, Xin Lai, Ahmad S. Rashidi, Georges M. G. M. Verjans, Line S. Reinert, Søren R. Paludan
Publikováno v:
J Virol
Katzilieris-Petras, G, Lai, X, Rashidi, A S, Verjans, G M G M, Reinert, L S & Paludan, S R 2022, ' Microglia Activate Early Antiviral Responses upon Herpes Simplex Virus 1 Entry into the Brain to Counteract Development of Encephalitis-Like Disease in Mice ', Journal of Virology, vol. 96, no. 6, e01311-21 . https://doi.org/10.1128/jvi.01311-21
Journal of Virology, 96(6):e01311-21
Katzilieris-Petras, G, Lai, X, Rashidi, A S, Verjans, G M G M, Reinert, L S & Paludan, S R 2022, ' Microglia Activate Early Antiviral Responses upon Herpes Simplex Virus 1 Entry into the Brain to Counteract Development of Encephalitis-Like Disease in Mice ', Journal of Virology, vol. 96, no. 6, e01311-21 . https://doi.org/10.1128/jvi.01311-21
Journal of Virology, 96(6):e01311-21
Spread of herpes simplex virus 1 (HSV1) from the periphery to the central nervous system (CNS) can lead to extensive infection and pathological inflammation in the brain, causing herpes simplex encephalitis (HSE). It has been shown that microglia, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9198d1603b1e0f27ea0e578efec32332
https://europepmc.org/articles/PMC8941881/
https://europepmc.org/articles/PMC8941881/