Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Line Nilsson"'
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Urinary obstruction is associated with inflammation and oxidative stress, leading to renal dysfunction. Previous studies have shown that 15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) has both antioxidant and anti-inflammatory effects. Using a unilater
Externí odkaz:
https://doaj.org/article/c239df92fa1342fba3faeac31ef39bd0
Autor:
Signe S. Tofteng, Line Nilsson, Amalie K. Mogensen, Rikke Nørregaard, Rolf Nüsing, Mikhail Diatchikhine, Lars Lund, Claus Bistrup, Boye L. Jensen, Kirsten Madsen
Publikováno v:
Tofteng, S S, Nilsson, L, Mogensen, A K, Nørregaard, R, Nüsing, R, Diatchikhine, M, Lund, L, Bistrup, C, Jensen, B L & Madsen, K 2022, ' Increased COX-2 after ureter obstruction attenuates fibrosis and is associated with EP 2 receptor upregulation in mouse and human kidney ', Acta Physiologica, vol. 235, no. 4, e13828 . https://doi.org/10.1111/apha.13828
Aim: Cyclooxygenase-2 (COX-2) activity protects against oxidative stress and apoptosis early in experimental kidney injury. The present study was designed to test the hypothesis that COX-2 activity attenuates fibrosis and preserves microvasculature i
Autor:
Signe S, Tofteng, Line, Nilsson, Amalie K, Mogensen, Rikke, Nørregaard, Rolf, Nüsing, Mikhail, Diatchikhine, Lars, Lund, Claus, Bistrup, Boye L, Jensen, Kirsten, Madsen
Publikováno v:
Acta physiologica (Oxford, England). 235(4)
Cyclooxygenase-2 (COX-2) activity protects against oxidative stress and apoptosis early in experimental kidney injury. The present study was designed to test the hypothesis that COX-2 activity attenuates fibrosis and preserves microvasculature in inj
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Nilsson, L, Palm, F & Norregaard, R 2017, ' 15-Deoxy-Delta(12,14)-prostaglandin J(2) Exerts Antioxidant Effects While Exacerbating Inflammation in Mice Subjected to Ureteral Obstruction ', Mediators of Inflammation . https://doi.org/10.1155/2017/3924912
Nilsson, L, Palm, F & Norregaard, R 2017, ' 15-Deoxy-Delta(12,14)-prostaglandin J(2) Exerts Antioxidant Effects While Exacerbating Inflammation in Mice Subjected to Ureteral Obstruction ', Mediators of Inflammation . https://doi.org/10.1155/2017/3924912
Urinary obstruction is associated with inflammation and oxidative stress, leading to renal dysfunction. Previous studies have shown that 15-deoxy-Δ12,14-prostaglandin J2(15d-PGJ2) has both antioxidant and anti-inflammatory effects. Using a unilatera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5eb4f4b34da39c8d619e837813d468d
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-322117
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-322117
Publikováno v:
Mediators of Inflammation
Urinary obstruction is associated with inflammation and oxidative stress, leading to renal dysfunction. Previous studies have shown that 15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) has both antioxidant and anti-inflammatory effects. Using a unilater
Autor:
Martin Bødtker Mortensen, Eirild Espeseth, Stine Gunnersen, Tore G. Larsen, Jacob F. Bentzon, Ernst-Martin Füchtbauer, Marie Bek, Ebbe Boedtkjer, Martin M. Bjørklund, Mette K. Hagensen, Anne Wolff, Line Nilsson
Publikováno v:
Mortensen, M B, Nilsson, L, Larsen, T G, Espeseth, E, Bek, M, Bjørklund, M M, Hagensen, M K, Wolff, A, Gunnersen, S, Füchtbauer, E-M, Boedtkjer, E & Bentzon, J F 2016, ' Prior renovascular hypertension does not predispose to atherosclerosis in mice ', Atherosclerosis, vol. 249, pp. 157-63 . https://doi.org/10.1016/j.atherosclerosis.2016.03.030
BACKGROUND: Hypertension is a major risk factor for development of atherosclerotic cardiovascular disease (ASCVD). Although lowering blood pressure with antihypertensive drugs reduces the increased risk of ASCVD, residual increased risk still remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::599a5e05c688c4848bb57de5e4f958e3
https://pure.au.dk/portal/da/publications/prior-renovascular-hypertension-does-not-predispose-to-atherosclerosis-in-mice(d956e0eb-418d-453f-8124-c45d18868eaf).html
https://pure.au.dk/portal/da/publications/prior-renovascular-hypertension-does-not-predispose-to-atherosclerosis-in-mice(d956e0eb-418d-453f-8124-c45d18868eaf).html
Autor:
James R. Woodgett, Rikke Nørregaard, Reena Rao, Shixin Tao, Christiana Howard, Vijayakumar R. Kakade, Alan S.L. Yu, Line Nilsson
Publikováno v:
Aarhus University
Nørregaard, R, Tao, S, Nilsson, L, Woodgett, J R, Kakade, V, Yu, A S, Howard, C & Rao, R 2015, ' Glycogen synthase kinase 3α regulates urine concentrating mechanism in mice ', American Journal of Physiology: Renal Physiology, vol. 308, pp. 650-660 .
Nørregaard, R, Tao, S, Nilsson, L, Woodgett, J R, Kakade, V, Yu, A S, Howard, C & Rao, R 2015, ' Glycogen synthase kinase 3α regulates urine concentrating mechanism in mice ', American Journal of Physiology: Renal Physiology, vol. 308, pp. 650-660 .
In mammals, glycogen synthase kinase (GSK)3 comprises GSK3α and GSK3β isoforms. GSK3β has been shown to play a role in the ability of kidneys to concentrate urine by regulating vasopressin-mediated water permeability of collecting ducts, whereas t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd29759fb4e86123ed29953a74826b9a
https://europepmc.org/articles/PMC4360031/
https://europepmc.org/articles/PMC4360031/
Autor:
Jørgen Frøkiær, Line Nilsson, Lene Stødkilde, Inge Carlsen, Yan Wang, Johan Palmfeldt, Rikke Nørregaard
Publikováno v:
Stødkilde-Jørgensen, L, Palmfeldt, J, Nilsson, L, Carlsen, I G, Wang, Y, Nørregaard, R & Frøkiær, J 2014, ' Proteomic identification of early changes in the renal cytoskeleton in obstructive uropathy ', A J P: Renal Physiology (Online), vol. 306, no. 12 . https://doi.org/10.1152/ajprenal.00244.2013
Bilateral ureteral obstruction (BUO) is associated with renal damage and impaired ability to concentrate urine and is known to induce alterations in an array of kidney proteins. The aim of this study was to identify acute proteomic alterations induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab6e2c5da7029b1cc27dac5082edf48
https://pure.au.dk/portal/da/publications/proteomic-identification-of-early-changes-in-the-renal-cytoskeleton-in-obstructive-uropathy(77ab6cd3-82b9-4adf-a95f-63eba250d0ff).html
https://pure.au.dk/portal/da/publications/proteomic-identification-of-early-changes-in-the-renal-cytoskeleton-in-obstructive-uropathy(77ab6cd3-82b9-4adf-a95f-63eba250d0ff).html
Publikováno v:
The FASEB Journal. 28
Renal oxidative stress is increased in response to ureteral obstruction. In vitro, COX-2 activity contributes to antioxidative protection. Here, we test the hypothesis that COX-2 activity counters ...
Publikováno v:
Madsen, K, Tofteng, S S, Nilsson, L, Jensen, B L & Nørregaard, R 2014, ' Impaired Cyclooxygenase-2 Expression Leads to Aggravated Renal Fibrosis in Response to Unilateral Ureteral Obstruction in Mice ', Annual Meeting of the American Society of Nephrology, Philadelphia, PA, USA, 11/11/2014-16/11/2014 .
University of Southern Denmark
Tofteng, S S, Madsen, K, Nilsson, L, Jensen, B L & Nørregaard, R 2016, ' Impaired cyclooxygenase-2 expression leads to aggravated renal fibrosis in response to unilateral ureteral obstruction in mice ', Scandinavian Physiological Society Annual Meeting, Århus, Denmark, 17/09/2015-20/09/2015 . < http://conferences.au.dk/sps2015aarhus/final-programme/ >
Madsen, K, Tofteng, S S, Nilsson, L, Jensen, B L & Nørregaard, R 2014, ' Impaired Cyclooxygenase-2 Expression Leads to Aggravated Renal Fibrosis in Response to Unilateral Ureteral Obstruction in Mice ', Journal of the American Society of Nephrology, bind 25, SA-PO405, s. 728A . < https://www.asn-online.org/abstracts/ >
University of Southern Denmark
Tofteng, S S, Madsen, K, Nilsson, L, Jensen, B L & Nørregaard, R 2016, ' Impaired cyclooxygenase-2 expression leads to aggravated renal fibrosis in response to unilateral ureteral obstruction in mice ', Scandinavian Physiological Society Annual Meeting, Århus, Denmark, 17/09/2015-20/09/2015 . < http://conferences.au.dk/sps2015aarhus/final-programme/ >
Madsen, K, Tofteng, S S, Nilsson, L, Jensen, B L & Nørregaard, R 2014, ' Impaired Cyclooxygenase-2 Expression Leads to Aggravated Renal Fibrosis in Response to Unilateral Ureteral Obstruction in Mice ', Journal of the American Society of Nephrology, bind 25, SA-PO405, s. 728A . < https://www.asn-online.org/abstracts/ >
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a14c34582929f8010a1e8e23b787b313
https://portal.findresearcher.sdu.dk/da/publications/6aa13341-da6c-4400-86ae-5534c091778a
https://portal.findresearcher.sdu.dk/da/publications/6aa13341-da6c-4400-86ae-5534c091778a