Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Line Nederby"'
Autor:
Sinne Søberg Brun, Torben Frøstrup Hansen, Sara Witting Christensen Wen, Christa Haugaard Nyhus, Lisbeth Bertelsen, Anders Jakobsen, Torben Schjødt Hansen, Line Nederby
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Many studies have focused on the prognostic role of soluble programmed death ligand 1 (sPD-L1) in non-small cell lung cancer (NSCLC), but outcomes are ambiguous and further investigations are needed. We addressed the matter by studying sPD-L
Externí odkaz:
https://doaj.org/article/de6468f3c6e3447088497815bde82608
Autor:
Paul W. Dempsey, Cristina-Mihaela Sandu, Ricardo Gonzalezirias, Spencer Hantula, Obdulia Covarrubias-Zambrano, Stefan H. Bossmann, Alykhan S. Nagji, Nirmal K. Veeramachaneni, Nezih O. Ermerak, Derya Kocakaya, Tunc Lacin, Bedrittin Yildizeli, Patrick Lilley, Sara W. C. Wen, Line Nederby, Torben F. Hansen, Ole Hilberg
Publikováno v:
Communications Medicine, Vol 4, Iss 1, Pp 1-9 (2024)
Abstract Background Lung cancer is associated with the greatest cancer mortality as it typically presents with incurable distributed disease. Biomarkers relevant to risk assessment for the detection of lung cancer continue to be a challenge because t
Externí odkaz:
https://doaj.org/article/134d8ce180d04e7ca4d08e080d2e680d
Publikováno v:
Clinical Hematology International, Vol 4, Iss 3, Pp 107-116 (2022)
Abstract Multiple myeloma is an incurable disease characterized by unregulated growth of malignant plasma cells in the bone marrow (BM). Tumor-induced dysfunction of T-cells may be responsible for immune evasion and failure of immunotherapy. Therefor
Externí odkaz:
https://doaj.org/article/269e2835dd4b42b4a7c2eca3e15280f6
Autor:
Morten Borg, Sara Witting Christensen Wen, Torben Frøstrup Hansen, Anders Jakobsen, Rikke Fredslund Andersen, Ole Hilberg, Ulla Møller Weinreich, Line Nederby
Publikováno v:
Journal of International Medical Research, Vol 50 (2022)
Objective Natural killer (NK) cells play an essential role in the immune response against cancer. However, immune escape mechanisms may cause inferior NK cell activity (NKA) in patients with cancer. This prospective study examined the relationship be
Externí odkaz:
https://doaj.org/article/98d79f5b73f64adfaed8e24a84beff98
Autor:
Jon Røikjær Henriksen, Line Nederby, Frede Donskov, Marianne Waldstrøm, Parvin Adimi, Anders Jakobsen, Karina Dahl Steffensen
Publikováno v:
Journal of Ovarian Research, Vol 13, Iss 1, Pp 1-9 (2020)
Abstract Purpose Biomarkers are needed to guide treatment decisions in recurrent ovarian cancer, as a high proportion of patients do not benefit from treatments. Data on immune subsets in patients receiving chemotherapy are scarce. We investigated th
Externí odkaz:
https://doaj.org/article/fb7aa638f37d4fd7b7004e3d055162c6
Autor:
Torben Frøstrup Hansen, Line Nederby, Ahmed H. Zedan, Inge Mejlholm, Jon R. Henriksen, Karina D. Steffensen, Caroline B. Thomsen, Louise Raunkilde, Lars Henrik Jensen, Anders Jakobsen
Publikováno v:
Translational Oncology, Vol 12, Iss 7, Pp 968-972 (2019)
INTRODUCTION: The aim of the present study was to analyze the possible correlation between Natural Killer (NK) cell activity as measured by the NK Vue assay and treatment efficacy in patients with disseminated cancer. MATERIALS AND METHODS: The study
Externí odkaz:
https://doaj.org/article/addddd0d570e43a1a92a4b84f831cd0d
Autor:
Marcus Celik Hansen, Line Nederby, Anne Roug, Palle Villesen, Eigil Kjeldsen, Charlotte Guldborg Nyvold, Peter Hokland
Publikováno v:
MethodsX, Vol 2, Iss C, Pp 145-153 (2015)
Sequencing the exome is quickly becoming the preferred method for discovering disease-inducing mutations. While obtaining data sets is a straightforward procedure, the subsequent analysis and interpretation of the data is a limiting step for clinical
Externí odkaz:
https://doaj.org/article/5316969cb95147378e0dc20890aeed15
Autor:
Marcus Celik Hansen, Line Nederby, Mads Okkels-Birk Henriksen, Maria Hansen, Charlotte Guldborg Nyvold
Publikováno v:
BioTechniques, Vol 56, Iss 5, Pp 217-228 (2014)
Quantitative PCR (qPCR) of reverse-transcribed mRNA has revolutionized gene expression analyses. qPCR analysis is based on the prevalent assumption that mRNA transcript numbers provide an adequate measure of specific biomarker expression. However, ta
Externí odkaz:
https://doaj.org/article/b5acc2cadce84abca5a45e1227c0bf03
Autor:
Marie Toft-Petersen, Eigil Kjeldsen, Line Nederby, Kirsten Grønbæk, Peter Hokland, Anne Stidsholt Roug
Publikováno v:
Leukemia Research Reports, Vol 3, Iss 2, Pp 94-97 (2014)
We have identified a novel 7.7 Mb del(8)(q23.2q24.11) in a patient progressing to acute myeloid leukemia (AML) following a 12-year stable phase of chronic myelomonocytic leukemia (CMML). A surprisingly high JAK2+ allelic burden of 92% at the time of
Externí odkaz:
https://doaj.org/article/c0ec27d5b21b40368f542913338e27fa
Autor:
Morten Borg, Line Nederby, Sara Witting Christensen Wen, Torben Frøstrup Hansen, Anders Jakobsen, Rikke Fredslund Andersen, Ulla Møller Weinreich, Ole Hilberg
Publikováno v:
Borg, M, Nederby, L, Wen, S W C, Hansen, T F, Jakobsen, A, Andersen, R F, Weinreich, U M & Hilberg, O 2023, ' Assessment of circulating biomarkers for detection of lung cancer in a high-risk cohort ', Cancer biomarkers, vol. 36, no. 1, pp. 63-69 . https://doi.org/10.3233/CBM-210543
BACKGROUND: There is an urgent need for early detection of lung cancer. Screening with low-dose computed tomography (LDCT) is now implemented in the US. Supplementary use of a lung cancer biomarker with high specificity is desirable.OBJECTIVE: To ass