Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Lindy L. Visser"'
Autor:
Jeff DeMartino, Michael T. Meister, Lindy L. Visser, Mariël Brok, Marian J. A. Groot Koerkamp, Amber K. L. Wezenaar, Laura S. Hiemcke-Jiwa, Terezinha de Souza, Johannes H. M. Merks, Anne C. Rios, Frank C. P. Holstege, Thanasis Margaritis, Jarno Drost
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Paediatric rhabdomyosarcoma (RMS) is a soft tissue malignancy of mesenchymal origin that is thought to arise as a consequence of derailed myogenic differentiation. Despite intensive treatment regimens, the prognosis for high-risk patients re
Externí odkaz:
https://doaj.org/article/6e17129946ec4b3cabd8153ddce619c9
Autor:
Mathilde M. M. Almekinders, Michael Schaapveld, Bram Thijssen, Lindy L. Visser, Tycho Bismeijer, Joyce Sanders, Edoardo Isnaldi, Ingrid Hofland, Marjolijn Mertz, Lodewyk F. A. Wessels, Annegien Broeks, Erik Hooijberg, Wilbert Zwart, Esther H. Lips, Grand Challenge PRECISION Consortium, Christine Desmedt, Jelle Wesseling
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Although ductal carcinoma in situ (DCIS) is a non-obligate precursor to ipsilateral invasive breast cancer (iIBC), most DCIS lesions remain indolent. Hence, overdiagnosis and overtreatment of DCIS is a major concern. There is an urgent need
Externí odkaz:
https://doaj.org/article/0a52b05e321f481ea6b0d325da202d72
Somatic mutations and copy number variations in breast cancers with heterogeneous HER2 amplification
Autor:
Mieke R. Van Bockstal, Marie Colombe Agahozo, Ronald van Marion, Peggy N. Atmodimedjo, Hein F. B. M. Sleddens, Winand N. M. Dinjens, Lindy L. Visser, Esther H. Lips, Jelle Wesseling, Carolien H. M. van Deurzen
Publikováno v:
Molecular Oncology, Vol 14, Iss 4, Pp 671-685 (2020)
Intratumour heterogeneity fuels carcinogenesis and allows circumventing specific targeted therapies. HER2 gene amplification is associated with poor outcome in invasive breast cancer. Heterogeneous HER2 amplification has been described in 5–41% of
Externí odkaz:
https://doaj.org/article/bab2d6a1b653450da771b3f429430417
Autor:
Camilla Calandrini, Frans Schutgens, Rurika Oka, Thanasis Margaritis, Tito Candelli, Luka Mathijsen, Carola Ammerlaan, Ravian L. van Ineveld, Sepide Derakhshan, Sanne de Haan, Emmy Dolman, Philip Lijnzaad, Lars Custers, Harry Begthel, Hindrik H. D. Kerstens, Lindy L. Visser, Maarten Rookmaaker, Marianne Verhaar, Godelieve A. M. Tytgat, Patrick Kemmeren, Ronald R. de Krijger, Reem Al-Saadi, Kathy Pritchard-Jones, Marcel Kool, Anne C. Rios, Marry M. van den Heuvel-Eibrink, Jan J. Molenaar, Ruben van Boxtel, Frank C. P. Holstege, Hans Clevers, Jarno Drost
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Pre-clinical cell culture models capturing the heterogeneity of childhood kidney tumours are limited. Here, the authors establish and characterise an organoid biobank of tumour and matched normal organoid cultures from over 50 children with different
Externí odkaz:
https://doaj.org/article/06e35408aaed4de9ae4266eeecb8d988
Autor:
Jelle Wesseling, Esther H. Lips, Marjanka K. Schmidt, Emiel J. Rutgers, Flora E. van Leeuwen, Carolien Bierman, Mathilde M. Almekinders, Emma J. Groen, Koen van de Vijver, Michael Schaapveld, Lotte E. Elshof, Lindy L. Visser
Supplementary Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad909b0466738989084561dd558e992
https://doi.org/10.1158/1078-0432.22469448.v1
https://doi.org/10.1158/1078-0432.22469448.v1
Autor:
Jelle Wesseling, Esther H. Lips, Marjanka K. Schmidt, Emiel J. Rutgers, Flora E. van Leeuwen, Carolien Bierman, Mathilde M. Almekinders, Emma J. Groen, Koen van de Vijver, Michael Schaapveld, Lotte E. Elshof, Lindy L. Visser
Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944a50ae81292475ceb29045ef71d428
https://doi.org/10.1158/1078-0432.22469451
https://doi.org/10.1158/1078-0432.22469451
Autor:
Jelle Wesseling, Esther H. Lips, Marjanka K. Schmidt, Emiel J. Rutgers, Flora E. van Leeuwen, Carolien Bierman, Mathilde M. Almekinders, Emma J. Groen, Koen van de Vijver, Michael Schaapveld, Lotte E. Elshof, Lindy L. Visser
Purpose: Ductal carcinoma in situ (DCIS) is treated to prevent progression to invasive breast cancer. Yet, most lesions will never progress, implying that overtreatment exists. Therefore, we aimed to identify factors distinguishing harmless from pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7ea44e88b8cc81f79240329fc69f8d
https://doi.org/10.1158/1078-0432.c.6527262.v1
https://doi.org/10.1158/1078-0432.c.6527262.v1
Autor:
Judith Wienke, Lindy L. Visser, Waleed M. Kholosy, Kaylee M. Keller, Marta Barisa, Sophie Munnings-Tomes, Elizabeth Carlton, Evon Poon, Ana Rodriguez, Ronald Bernardi, Femke van den Ham, Sander R. van Hooff, Yvette A.H. Matser, Michelle L. Tas, Karin P.S. Langenberg, Philip Lijnzaad, Josephine G.M. Strijker, Alvaro Sanchez-Bernabeu, Annelisa M. Cornel, Frank C.P. Holstege, Juliet Gray, Lieve A.M. Tytgat, Ronald R. de Krijger, Marijn A. Scheijde-Vermeulen, Marc H.W.A. Wijnen, Miranda Dierselhuis, Karin Straathof, Sam Behjati, Wei Wu, Albert J.R. Heck, Jan Koster, Stefan Nierkens, Louis Chesler, John Anderson, Hubert N. Caron, Thanasis Margaritis, Max M. van Noesel, Jan J. Molenaar
Pediatric patients with high-risk neuroblastoma have poor survival rates and urgently need more effective treatment options with less side effects. As novel and improved immunotherapies may fill this need, we dissected the immunoregulatory interactio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25012e4e18c571cc6fe4704c0cf8a9ab
https://doi.org/10.1101/2022.07.15.499859
https://doi.org/10.1101/2022.07.15.499859
Somatic mutations and copy number variations in breast cancers with heterogeneous HER2 amplification
Autor:
Marie Colombe Agahozo, Lindy L. Visser, Winand N.M. Dinjens, Jelle Wesseling, Ronald van Marion, Esther H. Lips, Carolien H.M. van Deurzen, Peggy N. Atmodimedjo, Hein F.B.M. Sleddens, Mieke Van Bockstal
Publikováno v:
Molecular Oncology
Molecular Oncology, 14(4), 671-685. John Wiley & Sons Ltd.
Molecular oncology, Vol. 14, no.4, p. 671-685 (2020)
Molecular Oncology, Vol 14, Iss 4, Pp 671-685 (2020)
Molecular Oncology, 14(4), 671-685. John Wiley & Sons Ltd.
Molecular oncology, Vol. 14, no.4, p. 671-685 (2020)
Molecular Oncology, Vol 14, Iss 4, Pp 671-685 (2020)
Intratumour heterogeneity fuels carcinogenesis and allows circumventing specific targeted therapies. HER2 gene amplification is associated with poor outcome in invasive breast cancer. Heterogeneous HER2 amplification has been described in 5–41% of
Autor:
Ingrid Hofland, Dennis Peters, Mathilde M. Almekinders, Michael Schaapveld, Lotte E. Elshof, Marjanka K. Schmidt, Lindy L. Visser, Carolien Bierman, Koen Van de Vijver, Emiel J. Th. Rutgers, Annegien Broeks, Emma J. Groen, Jelle Wesseling, Joyce Sanders, Esther H. Lips, Flora E. van Leeuwen
Publikováno v:
American Journal of Surgical Pathology. 43:1574-1582
Ductal carcinoma in situ (DCIS) is considered a potential precursor of invasive breast carcinoma (IBC). Studies aiming to find markers involved in DCIS progression generally have compared characteristics of IBC lesions with those of adjacent synchron