Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Lindy L. Thomsen"'
Autor:
Gerrit Koopman, Sam O. Hofman, Nathalie Louise Mathy, Jonathan L. Heeney, Peter Franz Ertl, Marguerite Koutsoukos, Daniella Mortier, Cathy van Wely, Phil Overend, Gerald Voss, Lindy L. Thomsen, Britta Wahren
Publikováno v:
Journal of General Virology. 89:540-5533
Current data suggest that prophylactic human immunodeficiency virus type 1 (HIV) vaccines will be most efficacious if they elicit a combination of adaptive humoral and T-cell responses. Here, we explored the use of different vaccine strategies in het
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d14cd75ceb758191322893070b7ef43d
https://doi.org/10.1099/vir.0.83384-0
https://doi.org/10.1099/vir.0.83384-0
Autor:
Federica Sallusto, Antonio Lanzavecchia, Lindy L. Thomsen, Martin Lipp, Alfonso Martín-Fontecha, Sara Brett, Craig Gerard
Publikováno v:
Nature Immunology. 5:1260-1265
Naive T cells are stimulated by antigen-presenting dendritic cells (DCs) in secondary lymphoid organs, but whether other types of cell participate in T cell priming is unclear. Here we show in mice that natural killer (NK) cells, which are normally e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32ff284c578ee99610e9ab711ad6423
https://doi.org/10.1038/ni1138
https://doi.org/10.1038/ni1138
Publikováno v:
Cancer Research. 64:5059-5062
Uric acid released from dying cells has been shown recently to act as a danger signal for the immune system, stimulating dendritic cell maturation and enhancing T-cell responses to foreign antigens. Stimulation of dendritic cell maturation by uric ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b0c992520fceeed6e0b64a720157ec2
https://doi.org/10.1158/0008-5472.can-04-1586
https://doi.org/10.1158/0008-5472.can-04-1586
Publikováno v:
Vaccine. 22:1799-1809
Imiquimod, an immune response modifier and inducer of cytokines in vitro and in vivo, has been shown to have potent antiviral and antitumour activity and to act as an adjuvant for protein vaccination. We have undertaken studies in mice to investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::037aa534477eafed3c7f9aff299f0b97
https://doi.org/10.1016/j.vaccine.2003.09.052
https://doi.org/10.1016/j.vaccine.2003.09.052
Publikováno v:
Cancer Research. 64:152-161
The roles played by host-derived nitric oxide (NO) in the growth and subsequent immune rejection of a immunogenic murine lymphoma were investigated by growing the tumor in mice in which the gene for either inducible NO synthase (iNOS) or endothelial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c527fde5b5d5f23621a7bdcd4a3761b7
https://doi.org/10.1158/0008-5472.can-03-1807
https://doi.org/10.1158/0008-5472.can-03-1807
Autor:
Lindy L. Thomsen, Peter Franz Ertl
Publikováno v:
Methods. 31:199-206
Delivery of antigen-encoding genes by nucleic acid vaccine vectors offers tremendous advantages in power and flexibility over conventional antigen delivery systems. Of the many forms of nucleic acid vaccine that can be constructed, circular DNA plasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f2414b18485188f77226478981524a9
https://doi.org/10.1016/s1046-2023(03)00134-8
https://doi.org/10.1016/s1046-2023(03)00134-8
Autor:
Olle Bjorkdahl, Maria G. Daly, Tite John Philip, Nabil Elshourbagy, C Plumpton, Lindy L. Thomsen, Karen A. Barber, Sara Brett
Publikováno v:
Immunology. 110:170-179
Expression of the lymph node homing and CC-chemokine receptor 7 (CCR7), with L-selectin (CD62L), has been shown to divide human memory T cells into two functionally distinct subsets. We generated a polyclonal antibody against murine CCR7 and used thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744e1bc821d37e20f62164eff2ee8dd3
https://doi.org/10.1046/j.1365-2567.2003.01727.x
https://doi.org/10.1046/j.1365-2567.2003.01727.x
Autor:
Kate L White, Sarah Marina Walcott, Michael A. Romanos, Andrew R. Lloyd, Elmer B. Santos, Gerald Wayne Gough, Philip K. Nicholls, Vanita Parmar, Lindy L. Thomsen, Davina M. Anderson, Richard A. Moore, Margaret Stanley, Peter Topley
Publikováno v:
Virology. 304(2):451-459
DNA plasmids encoding the open reading frames of canine oral papillomavirus (COPV) nonstructural early genes E1, E2, or E7 protein were delivered into both oral mucosal and cutaneous epithelial sites in beagle dogs using particle-mediated immunothera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c2d98a56723e45c5260f08b8d58983
Autor:
Benjamin M. Chain, Cathy A. van Wely, Tite John Philip, Remi J. Creusot, Lindy L. Thomsen, Peter Topley
Publikováno v:
Vaccine. 19:1678-1687
The early responses of CD4+ T cells to particle-mediated DNA immunisation were investigated using OVA-specific TCR-transgenic CD4+ T cells. Following adoptive transfer of these cells, mice were immunised by delivery into the skin of a plasmid encodin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81f750f1928da03c1fb339e754e0c128
https://doi.org/10.1016/s0264-410x(00)00405-9
https://doi.org/10.1016/s0264-410x(00)00405-9
Publikováno v:
Biochemical Pharmacology. 56:1365-1370
Recent studies suggest a dual role for nitric oxide (NO) in tumour biology. High concentrations of NO can mediate tumouricidal activity, whereas lower concentrations have been shown to promote tumour growth. In this study, NO synthase (NOS) activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926303968c687d7c0581a9c5828b58da
https://doi.org/10.1016/s0006-2952(98)00187-7
https://doi.org/10.1016/s0006-2952(98)00187-7