Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lindy A.M. Santegoets"'
Autor:
Senada Koljenović, Peter J. van der Spek, Sigrid M. A. Swagemakers, Patricia C. Ewing-Graham, Lindy A.M. Santegoets, Helena C. van Doorn, Thierry P P van den Bosch, Shatavisha Dasgupta, Folkert J. van Kemenade
Publikováno v:
Oncology Letters, 21(5):381. Spandidos Publications
Oncology Letters
Oncology Letters
Vulvar squamous cell carcinoma (VSCC) comprises two distinct etiopathological subtypes: i) Human papilloma virus (HPV)-related VSCC, which arises via the precursor high grade squamous intraepithelial lesion (HSIL); and ii) HPV-independent VSCC, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e0d2362945372f5741e854a7d41393a
https://doi.org/10.3892/ol.2021.12642
https://doi.org/10.3892/ol.2021.12642
Autor:
Lindy A.M. Santegoets, Annelinde Terlou, Marc van Beurden, Theo J.M. Helmerhorst, Leen J. Blok, Claudia Heijmans-Antonissen, Peter J. van der Spek, Sigrid M. A. Swagemakers, Patricia C. Ewing, Willem I. van der Meijden, Romy van Baars
Publikováno v:
International Journal of Cancer, 130(12), 2874-2885. Wiley-Liss Inc.
Human papillomavirus (HPV) infections may result in benign hyperplasia, caused by low-risk HPV types, or (pre)malignant lesions caused by high-risk HPV types. The molecular basis of this difference in malignant potential is not completely understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df386c6d60b32387b3086dc831817cc
https://pure.eur.nl/en/publications/38342252-c876-4736-8127-245138c23c23
https://pure.eur.nl/en/publications/38342252-c876-4736-8127-245138c23c23
Autor:
Manon van Seters, Lindy A.M. Santegoets, Theo J.M. Helmerhorst, Ilse Beckmann, Annelinde Terlou, Marc van Beurden, Claudia Heijmans-Antonissen, Alex KleinJan, Leen J. Blok
Publikováno v:
International Journal of Cancer, 128(10), 2463-2469. Wiley-Liss Inc.
Imiquimod has been shown to be an effective treatment for usual type vulvar intraepithelial neoplasia (uVIN). Since local inflammation and burning are common side effects, patients often use nonsteroidal anti-inflammatory drugs (NSAIDs). Our study in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71e2b94f4a881bff98763d675ba93a0
https://pure.eur.nl/en/publications/12a8bf62-dc6b-4277-830c-ea92894e3fdd
https://pure.eur.nl/en/publications/12a8bf62-dc6b-4277-830c-ea92894e3fdd
Autor:
Patricia C. Ewing, Manon van Seters, Ilse Beckmann, Lindy A.M. Santegoets, Marc van Beurden, Liesbeth C.M. Kühne, Theo J.M. Helmerhorst, Claudia Heijmans-Antonissen, Curt W. Burger, Alex KleinJan, Leen J. Blok
Publikováno v:
International Journal of Cancer. 123:616-622
Usual type VIN is a premalignant disorder caused by persistent HPV infection. High prevalence of VIN in immuno-suppressed women suggests that a good innate and adaptive immune response is important for defense against HPV. Here, we explored expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd1444d4fc172b6e4139ab2cd5d28cc4
https://doi.org/10.1002/ijc.23545
https://doi.org/10.1002/ijc.23545
Autor:
Susanne C.J.P. Gielen, Lindy A.M. Santegoets, Leen J. Blok, Payman Hanifi-Moghaddam, Curt W. Burger
Publikováno v:
Journal of Steroid Biochemistry and Molecular Biology, 109(3-5), 219-223. Elsevier Ltd.
Tamoxifen is used as adjuvant treatment for postmenopausal breast cancer patients. The mechanism of action of tamoxifen in breast cancer patients is that tamoxifen inhibits growth of cancer cells by competitive antagonism for estrogens at the estroge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b419fe4dad718258bc9b5370462e63cb
https://doi.org/10.1016/j.jsbmb.2008.03.021
https://doi.org/10.1016/j.jsbmb.2008.03.021
Autor:
Jan Lindemans, Ben A. Oostra, Annelies de Klein, Bart J. B. Bliek, Régine P.M. Steegers-Theunissen, Eric A.P. Steegers, Leen J. Blok, Lindy A.M. Santegoets
Publikováno v:
Birth Defects Research Part A-Clinical and Molecular Teratology, 82(9), 627-635. Wiley-Liss Inc.
BACKGROUND: A cleft of the lip with or without the palate (CLP) is a frequent congenital malformation with a heterogeneous etiology, for which folic acid supplementation has a protective effect. To gain more insight into the molecular pathways affect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1a119f3b01a6a5c3eea81e9fb416e3
https://hdl.handle.net/1765/14902
https://hdl.handle.net/1765/14902
Autor:
Wilfred F. J. van IJcken, Lindy A.M. Santegoets, Manon van Seters, Patricia C. Ewing, Leen J. Blok, Theo J.M. Helmerhorst, Payman Hanifi-Moghaddam, Claudia Heijmans-Antonissen, Willem I. van der Meijden, Peter J. van der Spek
Publikováno v:
International Journal of Cancer, 121(4), 759-766. Wiley-Liss Inc.
Vulvar intraepithelial neoplasia (VIN) is a premalignant disorder caused by human papillomaviruses. Basic knowledge about the molecular pathogenesis of VIN is sparse. Therefore, we have analyzed the gene expression profile of 9 VIN samples in compari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb930a005b04a121a45111711d46292
https://doi.org/10.1002/ijc.22769
https://doi.org/10.1002/ijc.22769
Autor:
Annelinde Terlou, Patricia C. Ewing, Marc van Beurden, Claudia Heijmans-Antonissen, Peter J. van der Spek, Sigrid M.A. Swagemakers, Willem I. van der Meijden, Lindy A.M. Santegoets, Theo J.M. Helmerhorst, Leen J. Blok
Publikováno v:
Journal of Investigative Dermatology, 132(3), 658-666. Nature Publishing Group
Vulvar lichen sclerosus and lichen planus are T-cell–mediated chronic skin disorders. Although autoimmunity has been suggested, the exact pathogenesis of these disorders is still unknown. Therefore, the aim of the current study was to investigate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77941177d6dfa3f91aa347960789910
https://pubmed.ncbi.nlm.nih.gov/22113482
https://pubmed.ncbi.nlm.nih.gov/22113482
Publikováno v:
Journal of Lower Genital Tract Disease, 14(4), 323-328. Lippincott Williams & Wilkins
Objective The aim of this retrospective clinical study was to evaluate clinical features, histopathology, treatment regimen, and follow-up in 95 patients with genital lichen planus. Materials and methods We retrospectively analyzed data of 95 women d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be27331b83f94b311b816555f90a7423
https://pubmed.ncbi.nlm.nih.gov/20885160
https://pubmed.ncbi.nlm.nih.gov/20885160
Autor:
Wilfred F. J. van IJcken, Liesbeth C.M. Kühne, Leen J. Blok, Sussane C. J. P. Gielen, Curt W. Burger, Bianca Boers-Sijmons, Payman Hanifi-Moghaddam, Lindy A.M. Santegoets, Theo J.M. Helmerhorst
Publikováno v:
Reproductive Sciences, 14(7), 646-654. SAGE Publishing
For the endometrium, estradiol and tamoxifen induce proliferation, and consequently, tamoxifen treatment of breast cancer results in a 2-fold to 7-fold increased risk for endometrial cancer. Here, the role of activation of growth factor receptor sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d303520446b839f4d880945d1934296d
https://pure.eur.nl/en/publications/57943bec-ae7a-4dff-a203-7a9953fe0138
https://pure.eur.nl/en/publications/57943bec-ae7a-4dff-a203-7a9953fe0138
