Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Lindsey Shapiro"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Voltage-gated sodium channel genes are an important family of human epilepsy genes. De novo missense mutations in SCN8A (encoding Nav1.6) are associated with a spectrum of clinical presentation, including multiple seizure types, movement disorders, i
Externí odkaz:
https://doaj.org/article/37a071cf77bd48d2975b51d2ce041402
Autor:
Jennifer C. Wong, Kameryn M. Butler, Lindsey Shapiro, Jacquelyn T. Thelin, Kari A. Mattison, Kathryn B. Garber, Paula C. Goldenberg, Shobana Kubendran, G. Bradley Schaefer, Andrew Escayg
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Numerous SCN8A mutations have been identified, of which, the majority are de novo missense variants. Most mutations result in epileptic encephalopathy; however, some are associated with less severe phenotypes. Mouse models generated by knock-in of hu
Externí odkaz:
https://doaj.org/article/f765ae8f391a48a3a868a1a5685cd432
Autor:
Jennifer C. Wong, Lindsey Shapiro, Jacquelyn T. Thelin, Elizabeth C. Heaton, Rokon U. Zaman, Martin J. D'Souza, Kevin S. Murnane, Andrew Escayg
Publikováno v:
Neurobiology of Disease, Vol 147, Iss , Pp 105147- (2021)
Oxytocin (OT) has broad effects in the brain and plays an important role in cognitive, social, and neuroendocrine function. OT has also been identified as potentially therapeutic in neuropsychiatric disorders such as autism and depression, which are
Externí odkaz:
https://doaj.org/article/da07d2b5600140dbb96d83635c2c3829
Autor:
Chad R. Camp, Lindsey Shapiro, Anna Vlachos, Riley E. Perszyk, Nima Shariatzadeh, Jacob White, Russell Sanchez, Sookyong Koh, Andrew Escayg, Christopher McBain, Kenneth Pelkey, Stephen F. Traynelis
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf7b5cf51aaaaf05408c84a4f29a195d
https://doi.org/10.1096/fasebj.2022.36.s1.r6059
https://doi.org/10.1096/fasebj.2022.36.s1.r6059
Autor:
Chad R. Camp, Lindsey Shapiro, Anna Vlachos, Riley E. Perszyk, Nima Shariatzadeh, Jacob White, Russell Sanchez, Sookyong Koh, Andrew Escayg, Hongjie Yuan, Chris J. McBain, Kenneth A. Pelkey, Stephen F. Traynelis
N-methyl-D-aspartate receptors (NMDARs) are excitatory glutamate-gated ion channels that are expressed throughout the central nervous system. NMDARs mediate calcium entry into cells, and are involved in a host of neurological functions, including neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe86330770a360b71cef31410281fc9
https://doi.org/10.1101/2021.12.29.474447
https://doi.org/10.1101/2021.12.29.474447
Publikováno v:
Frontiers in pharmacology. 13
Voltage-gated sodium channel genes are an important family of human epilepsy genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbf5061f532d1250440dd7d8f1654eec
https://pubmed.ncbi.nlm.nih.gov/35153788
https://pubmed.ncbi.nlm.nih.gov/35153788
Publikováno v:
Biological Journal of the Linnean Society. 125:61-71
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::480c21b5c340b3ea15a7f06b5f571ed9
https://doi.org/10.1093/biolinnean/bly097
https://doi.org/10.1093/biolinnean/bly097
Publikováno v:
Innovation in Aging
The magnitude of COVID-19 mortality in adult congregate living settings other than nursing homes (NH) is unknown. To address this, we created an individual property level dataset for five U.S. states (Colorado, Connecticut, Florida, Georgia, and Penn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4c3aad6a67c09e5f4764f78d4d50fc
http://europepmc.org/articles/PMC8680393
http://europepmc.org/articles/PMC8680393
Autor:
James J. Yoo, Sang Jin Lee, Peter M. Prim, James H. Kaan, John D. Jackson, Anthony Atala, Jae Sung Lee, Lindsey Shapiro, Han Su Kim
Publikováno v:
Wound Repair and Regeneration. 25:398-407
For treatments requiring split-thickness skin grafts, it is preferable to mesh the grafts. This reduces the amount of excised skin and covers more wound area. The mesh technique, however, destroys surface continuity, which results in scarring. Strain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::545083687a9b02720443238647c8c42c
https://doi.org/10.1111/wrr.12550
https://doi.org/10.1111/wrr.12550
Publikováno v:
Neuropharmacology. 188:108448
Mounting evidence suggests that modulation of cannabinoid 2 receptors (CB2Rs) is therapeutic in mouse models of neurological disorders, including neuropathic pain, neurodegenerative disease, and stroke. We previously showed that reducing CB2R activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2785717d4bc31556bb849a1fcd43a73
https://doi.org/10.1016/j.neuropharm.2021.108448
https://doi.org/10.1016/j.neuropharm.2021.108448